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  1. The purpose of this study was to evaluate and compare the feasibility, safety, and efficacy of conventional open pedicle screw fixation (COPSF), percutaneous pedicle screw fixation (PPSF), and paraspinal poste...

    Authors: Chao Zhu, Bin Wang, Jian Yin and Xin Hui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:306

    Content type: Research article

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  2. Soft tissue balancing is essential for the success of total knee arthroplasty (TKA) and is mainly dependent on surgeon-defined assessment (SDA) or a gap-balancer (GB). However, an electronic sensor has been de...

    Authors: Ran Zhao, Yanqing Liu and Hua Tian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:305

    Content type: Research article

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  3. This systematic review was conducted to gather available evidence on the effectiveness of muscle pedicle bone flap transplantation in adult patients with femoral neck fractures.

    Authors: Yipeng Wu, Muguo Song, Guangliang Peng, Yongqing Xu, Yang Li, Mingjie Wei, Hui Tang, Qian Lv, Teng Wang and Xingbo Cai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:304

    Content type: Systematic review

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  4. Previous study showed that circular RNA Absent-Small-Homeotic-2--Like protein (circASH2L) was higher in rheumatoid arthritis (RA) patients. However, the roles and mechanisms of circASH2L in RA progression rema...

    Authors: Xia Li, Meiting Qu, Jie Zhang, Kuanyin Chen and Xianghui Ma

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:302

    Content type: Research article

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  5. Congenital pseudoarthrosis of the clavicle (CPC) is an uncommon entity. Owing to its scarce presentation, treatment of this disorder has not been well established. This study aimed (1) to compare surgical trea...

    Authors: Jin Li, Sheng Ping Tang, Hai Bo Mei, Jing Fan Shao, Bao Jie Shi, Hai Qiang Wang and Xin Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:301

    Content type: Research article

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  6. To analyze the effect of sacrificing the posterior cruciate ligament (PCL) on the early postoperative outcome of cruciate retaining (CR) highly congruent rotating platform TKA.

    Authors: Long Chen, Jie Xu, Yuan Lin, Fen Qi Luo and Yu Guo Yu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:299

    Content type: Research article

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  7. We aimed to evaluate reliability, radiological outcomes, and the impacts of anterior cervical hybrid construction on the adjacent segments for the multilevel cervical degenerative disc disease (mCDDD) and spon...

    Authors: Murat Yilmaz, Kemal Yucesoy, Resat S. Erbayraktar and Rıfat S. Altinag

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:298

    Content type: Research article

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  8. Angiotensin II (Ang II) is associated with rheumatoid arthritis (RA) development. The present study investigated the impact of Ang II on the expression of receptor activator of nuclear factor-κB ligand (RANKL)...

    Authors: Zhiping Zhao, Yongtao Zhang, Changyao Wang, Xiangyu Wang, Yingzhen Wang and Haining Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:297

    Content type: Research article

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  9. To explore the impact of different repair methods for a lateral meniscus posterior root tear on the biomechanics of the knee joint using finite element analysis.

    Authors: Jian-Yu Wang, Yan-Song Qi, Hu-Ri-Cha Bao, Yong-Sheng Xu, Bao-Gang Wei, Yong-Xiang Wang, Bing-Xian Ma, Hui-Wen Zhou and Fei Lv

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:296

    Content type: Research article

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  10. In tibial plateau fractures (TPF) the restoration of an anatomical joint surface as well as an exact subchondral screw position for postoperative stability is crucial for the outcome.

    Authors: F. Souleiman, R. Henkelmann, J. Theopold, J. Fakler, U. Spiegl and P. Hepp

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:295

    Content type: Research article

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  11. Osteosarcoma is a disease with high mortality in children and adolescents, and metastasis is one of the important clinical features of osteosarcoma. N6-Methyladenosine (m6A) is the most abundant methylation modif...

    Authors: Hua Liu, Guangzhen Qin, Yanan Ji, Xiaojian Wang, Hailin Bao, Xiaojun Guan, Aichun Wei and Zhigang Cai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:294

    Content type: Research article

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  12. Peritendinous adhesion is among the common complications after tendon injury. Numerous studies have been carried out to prevent its formation, including modifications of surgical procedures, postoperative care...

    Authors: Pengfei Li, Haiying Zhou, Tian Tu and Hui Lu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:293

    Content type: Research article

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  13. Culture-negative periprosthetic joint infections (PJIs) can complicate diagnosis and management of PJI. This study aimed to identify risk factors for culture-negative PJI and differences in clinical characteri...

    Authors: Shintaro Watanabe, Naomi Kobayashi, Akito Tomoyama, Hyonmin Choe, Etsuko Yamazaki and Yutaka Inaba

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:292

    Content type: Research article

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  14. Some unusual rotator cuff (RC) tears are located in more proximal tendinous portions, with substantial remnant tissue attached to the footprint. The two options for surgical repair are sacrificing or preservin...

    Authors: Hyung-Suk Choi, Byung-Ill Lee, Jae-Hyung Kim, Hyung-Ki Cho and Gi-Won Seo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:291

    Content type: Technical note

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  15. Osteoarthritis (OA) is a complex joint disease and chronic pain source, affecting a patient’s quality of life and posing a financial burden. As the dog is considered a nearly ideal species for translation rese...

    Authors: J. C. Alves, Ana Margarida Moniz Pereira dos Santos, Patrícia Jorge, Catarina Falcão Trigoso Vieira Branco Lavrador and L. Miguel Carreira

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:290

    Content type: Research article

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  16. Lateral tibial plateau fractures (TPFs) are often treated with conventional open reduction and internal fixation (ORIF) through standard anterolateral sub-meniscal arthrotomy. There has been increasing support...

    Authors: Xiangtian Deng, Hongzhi Hu, Yiran Zhang, Weijian Liu, Qingcheng Song, Xiaodong Cheng, Jian Zhu, Sifan Yang, Zhipeng Ye, Haitao Guan, Boyu Zhang, Zhanle Zheng and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:289

    Content type: Research article

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  17. The long pentraxin PTX3 is generating great interest given the recent discovery of its involvement in bone metabolism. This study investigates the role of circulating PTX3 as a marker of bone-related phenotype...

    Authors: Virginia Veronica Visconti, Chiara Greggi, Simona Fittipaldi, Donato Casamassima, Maria Grazia Tallarico, Francesco Romano, Annalisa Botta and Umberto Tarantino

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:288

    Content type: Research article

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  18. To describe a new technique for implanting a double-bundle titanium cable to treat acromioclavicular (AC) joint dislocation via the new guider, and evaluate clinic outcomes.

    Authors: Jun Wang, Yongfeng Cui, Yuhang Zhang and Hang Yin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:287

    Content type: Research article

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  19. This study is to describe the design and surgical techniques of three- dimensional-printed porous implants for proximal giant cell tumors of bone and evaluate the short-term clinical outcomes.

    Authors: Yuqi Zhang, Minxun Lu, Li Min, Jie Wang, Yitian Wang, Yi Luo, Yong Zhou, Hong Duan and Chongqi Tu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:286

    Content type: Research article

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  20. To investigate the clinical efficacy of locking compression plate fixation for the treatment of femoral intertrochanteric fractures in patients with preexisting proximal femoral deformity.

    Authors: Shan Fan, Mingming Yin, Yibo Xu, Cheng Ren, Teng Ma, Yao Lu, Ming Li, Zhong Li and Kun Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:285

    Content type: Research article

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  21. To evaluate the effect of postoperative BP treatment on improving the fusion rate after lumbar spinal fusion surgery by performing a meta-analysis of randomized controlled trials (RCTs) and other comparative c...

    Authors: Jun Mei, Xiaoxu Song, Xiaoming Guan, Dou Wu, Junjie Wang and Qiang Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:284

    Content type: Research article

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  22. Platelet-rich plasma (PRP) has been used to favor anterior cruciate ligament (ACL) healing after reconstruction surgeries. However, clinical data are still inconclusive and subjective about PRP. Thus, we propo...

    Authors: Allan Felipe Fattori Alves, José Ricardo de Arruda Miranda, Sérgio Augusto Santana de Souza, Ricardo Violante Pereira, Paulo Roberto de Almeida Silvares, Seizo Yamashita, Elenice Deffune and Diana Rodrigues de Pina

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:283

    Content type: Research article

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  23. Osteoarthritis of the knee is a common degenerative joint disorder in our ageing population. A combination of thermal therapy with a self-management exercise have shown a positive effect in the management of o...

    Authors: Kevin Ki-Wai Ho, Anthony Wai-Leung Kwok, Wai-Wang Chau, S. M. Xia, Y. L. Wang and Jack Chun-Yiu Cheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:282

    Content type: Research article

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  24. Nonunion is a rare complication for distal fibular fractures. However, when there is a high degree of comminution, nonunion may occur. In this article, we describe a novel technique that uses the oblong hole o...

    Authors: Young Uk Park, Sung Jae Kim and Hyong Nyun Kim

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:281

    Content type: Research article

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  25. The overarching goal of our research was to compare the clinical and radiological outcomes with different sizes of cages implantation in anterior cervical discectomy and fusion (ACDF), and to evaluate the effe...

    Authors: Changyan Wu, Xiaojuan Yang, Xu Gao, Liwei Shao, Fang Li, Yunxin Sun, Xiaoyu Liu, Shuaihao Yao and Yifu Sun

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:280

    Content type: Research article

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  26. Curculigoside is a natural phenolic glycoside compound produced by Curculigo orchioides Gaertn. This study aimed to explore the effects of curculigoside in promoting the osteogenic differentiation of adipose-deri...

    Authors: Wei-Li You and Zheng-Long Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:279

    Content type: Research article

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  27. The association of the severity of clinical symptoms and level of functional performance with the degree of magnetic resonance imaging abnormalities in patients with lateral epicondylitis has not been fully el...

    Authors: Seok Woo Hong, Jeong-Hyun Kang, Jin Hun Park, Ji Na Kim, Hee Jin Park and Eugene Kim

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:278

    Content type: Research article

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  28. To explore the clinical efficacy of posterior LFF for cervical OPLL with radicular pain of upper limbs

    Authors: Bao Su, Jieliang Shen, Xiaoji Luo, Zhengxue Quan, Dianming Jiang, Xiaohua Peng and Ke Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:277

    Content type: Research article

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  29. Higher pedicle screw density posterior spinal fusion (PSF) constructs have not been shown to result in improved curve correction in Lenke 1 and 5 adolescent idiopathic scoliosis (AIS) but do increase cost. The...

    Authors: Timothy J. Skalak, Joel Gagnier, Michelle S. Caird, Frances A. Farley and Ying Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:276

    Content type: Research article

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  30. Hemophilic pseudotumor (HPT)-related fracture is a rare but severe complication in patients with HPTs. These fractures often occur in femurs. There is no consensus on the standard surgical protocol for HPT-rel...

    Authors: Keyu Chen, Guiyong Jiang, Yaowen Xu, Yunping Yang, Zexiong Mao, Jiaxin Lv, Fei Liu and Bin Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:275

    Content type: Research article

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  31. To develop and validate a nomogram useful in predicting recurrent lumbar disk herniation (rLDH) within 6 months after percutaneous endoscopic lumbar discectomy (PELD).

    Authors: Mengxian Jia, Yadong Sheng, Guoliang Chen, Wenbin Zhang, Jiajin Lin, Sheng Lu, Fayi Li, Jinwei Ying and Honglin Teng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:274

    Content type: Research article

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  32. The purpose of present study was to identify the differentially expressed genes (DEGs) associated with BMP-9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) by using bioinformatics methods.

    Authors: Jia-qi Wu, Lin-bo Mao, Ling-feng Liu, Yong-mei Li, Jian Wu, Jiao Yao, Feng-huan Zhang, Ting-yu Liu and Ling Yuan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:273

    Content type: Research article

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  33. The purpose of the current study was to explore the role and underlying mechanism of cellular retinoic acid binding protein 2 (CRABP2) in dexamethasone (DEX)-induced apoptosis in human osteoblast cells.

    Authors: Haiping Zhang, Ziliang Yu, Farui Sun and Jin Jin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:272

    Content type: Research article

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  34. Posterior hemivertebra resection and short-segment fusion with pedicle screws are an established treatment in congenital scoliosis, which require pediatric-specific instrumentation. The purpose of this study w...

    Authors: Mohammad Zarei, Ehsan Ghadimi, Nima Bagheri, Seyed Mir Mansour Moazen Jamshidi, Alireza Moharrami, Mersad Moosavi and Soroush Baghdadi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:271

    Content type: Research article

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  35. Implant-associated infections depict a major challenge in orthopedics and trauma surgery putting a high burden on the patients and health care systems, strongly requiring improvement of infection prevention an...

    Authors: Nike Walter, Daniel Popp, Viola Freigang, Michael Nerlich, Volker Alt and Markus Rupp

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:270

    Content type: Research article

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  36. Sacral insufficiency fracture (SIF) is rarer than osteoporotic vertebral compression fracture that occurs at other levels of the thoracolumbar spine. Percutaneous sacroplasty can effectively relieve pain and i...

    Authors: Feng-Chen Kao, Yao-Chun Hsu, Tzu-Shan Chen, Pao-Hsin Liu and Yuan-Kun Tu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:269

    Content type: Research article

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  37. To analyze and compare the effects of peri-treatment analgesics on acute and chronic pain and postoperative functional recovery of patients with thoracolumbar fractures, so as to guide the clinical drug use.

    Authors: Hao Yuan, Quan-Yuan Chang, Jie Chen, Ya-Ting Wang, Zong-Jin Gan, Song Wen, Ting-Ting Li and Liu-Lin Xiong

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:268

    Content type: Research article

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  38. The objectives of this study were to assess radiolucent lines around a highly porous titanium cup (Tritanium) using digital tomosynthesis and to investigate the clinical and radiographic factors associated wit...

    Authors: Kazuki Oishi, Yuji Yamamoto, Yoshifumi Harada, Ryo Inoue, Eiji Sasaki and Yasuyuki Ishibashi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:266

    Content type: Research article

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  39. Surgical site infection (SSI) is a risk in every operation. Infections negatively impact patient morbidity and mortality and increase financial demands. The aim of this study was to analyse SSI and its risk fa...

    Authors: Vera Spatenkova, Ondrej Bradac, Zdenek Jindrisek, Jan Hradil, Daniela Fackova and Milada Halacova

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:265

    Content type: Research article

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  40. Isolated patellofemoral osteoarthritis (PF-OA) is a common subtype of knee osteoarthritis, leading to a huge economic burden on health care systems. Although previous studies have shown that patellofemoral art...

    Authors: Guanrong Peng, Min Liu, Zhenhua Guan, Yunfei Hou, Qiang Liu, Xiaobo Sun, Xingyang Zhu, Wenjun Feng, Jianchun Zeng, Zhangrong Zhong and Yirong Zeng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:264

    Content type: Research article

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  41. Unfractionated heparin (UFH) and low molecular weight heparin (LMWH) are commonly used for preventing venous thrombosis of the lower extremity in patients with traumatic spinal cord injury. Although, LMWH is t...

    Authors: Ze Lin, Yun Sun, Hang Xue, Lang Chen, Chenchen Yan, Adriana C. Panayi, Bobin Mi and Guohui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:262

    Content type: Systematic review

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  42. Many non-union animal models have been developed to explore the problems surrounding fracture healing. However, the existing models are not perfect and cannot satisfy all non-union studies. This study aimed to...

    Authors: Xue-Qiang Wu, Dong Wang, Yang Liu and Jun-Lin Zhou

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:261

    Content type: Research article

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  43. This study was aimed to utilize a modified anterior drawer test (MADT) to detect the anterior cruciate ligament (ACL) ruptures and investigate its accuracy compares with three traditional tests.

    Authors: Guang-lei Zhao, Jin-yang Lyu, Chang-quan Liu, Jian-guo Wu, Jun Xia and Gang-yong Huang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:260

    Content type: Research article

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  44. Osteoarthritis (OA) is a worldwide musculoskeletal disorder. However, disease-modifying therapies for OA are not available. Here, we aimed to characterize the molecular signatures of OA and to identify novel t...

    Authors: Song Shi, Fuyin Wan, Zhenyu Zhou, Ran Tao, Yue Lu, Ming Zhou, Fan Liu and Yake Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:259

    Content type: Research article

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  45. The management of complex diabetic foot wounds with large skin defects poses a challenge for surgeons. We presented a simple skin stretching system and negative pressure wound therapy for the repair of complex...

    Authors: Yaojun Wu, Liang Chen, Shaokun Wu, Liying Yu, Mimi Chen, Jingnan Wang, Jiejie Chen and Qingjiang Pang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:258

    Content type: Study protocol

    Published on:

  46. Acromial fractures are rare and there is no consensus on fixation, but an increasing number of studies have reported using two screws to fix Ogawa type I acromial fractures. The objective of this study was to ...

    Authors: Wei Zhang, Zhongye Sun, Weiyan Li, Jun Yan, Liren Han, Shizhang Han, Xiaofei Yang and Bei Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:257

    Content type: Research article

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  47. Accurate femoral neck anteversion angle (FNA) measurement is of great significance in the diagnosis and treatment of developmental dysplasia of the hip (DDH) in children. The FNA measurement still remains a co...

    Authors: Zhencun Cai, Chengzhe Piao, Tianyu Zhang, Lianyong Li and Liangbi Xiang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:256

    Content type: Research article

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