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  1. To explore the influence of irrigating fluid at different temperatures on patients' body temperature and local inflammatory mediators during spinal endoscopy.

    Authors: Maji Sun, Fuchao Chu, Lidong Zhang, Rui Zhao, Xiaona Liu, Huilin Yu, Bin Pan, Jibin Wu and Feng Yuan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:336
  2. Osteolysis is one of the most prevalent clinical complications affecting people who undergo total joint replacement (TJR). Wedelolactone (WDL) is a coumestan compound derived from the Wedelia chinensis plant and ...

    Authors: Yung-Chang Lu, Ting-Kuo Chang, Tzu-Chiao Lin, Shu-Ting Yeh, Hsu-Wei Fang, Chun-Hsiung Huang and Chang-Hung Huang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:335
  3. With increasing life expectancy, declining mortality, and birth rates, the world's geriatric population is increasing. Falls in the older people are one of the most common and serious problems. Injuries from f...

    Authors: Nader Salari, Niloofar Darvishi, Melika Ahmadipanah, Shamarina Shohaimi and Masoud Mohammadi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:334
  4. Osteoarthritis (OA) is the most common musculoskeletal disease, and it has a complex pathology and unknown pathogenesis. Chondrocyte ferroptosis is closely associated with the development of OA. As a common dr...

    Authors: Jiangbo Yan, Gangning Feng, Long Ma, Zhirong Chen and Qunhua Jin
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:333
  5. As a skeletal malignancy, osteosarcoma has high incidence among primary malignant bone tumors. With increasing researches on molecules which mediate cancer progression, molecular mechanism has gradually become...

    Authors: Ou Shuang, Jianmin Zhou, Zijun Cai, Longteng Liao, Yuehua Wang, Wenyu Wang and Meng Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:332
  6. Managing periprosthetic joint infections are variable in practices. Debridement, antibiotics, and implant retention (DAIR) is one of the favorable interventions. Given that the success rate of the two-stage re...

    Authors: Yanchao Zhang, Zhisen Gao, Ti Zhang, Yu Dong, Zhuoqi Sheng, Fei Zhang, Yonggang Zhou and Lingfei Guo
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:330
  7. There is no consensus on intraoperative references for the posterior tibial slope (PTS) in medial unicompartmental knee arthroplasty (UKA). An arthroscopic hook probe placed on the medial second quarter of the...

    Authors: Masao Akagi, Hisafumi Aya, Shigeshi Mori, Nobuhisa Syogaku, Ichiro Tsukamoto and Akihiro Moritake
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:329
  8. The Mayo Elbow Performance Score (MEPS) is a rating system consisting of four dimensions to evaluate elbow performance. It is a common tool for assessment of elbow impairments worldwide. We determined the vali...

    Authors: A. Papen, T. Schöttker-Königer, A. Schäfer, F. Morrison, B. Hollinger, K. J. Burkhart, R. Nietschke, A. Zimmerer, N. Maffulli, F. Migliorini and Marco M. Schneider
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:328
  9. Avulsion fracture of the tibial intercondylar eminence is a rare injury, which mainly occurs in adolescents aged 8–14 years and in those with immature bones. The current commonly used surgery may result in sev...

    Authors: Libo Yuan, Rongmao Shi, Zhian Chen, Wei Ding and Hongbo Tan
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:327
  10. A modified local transposition flap (we call it “parallelogram flap”) surgery was performed for fingertip injuries. This study aimed to compare the clinical effects of parallelogram flap and homodigital island...

    Authors: Yingkai Zhang, Yao Wang, Xianwei He, Jiaqi Zhou, Guoping Cai and Rongbo Wu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:326
  11. To investigate the biomechanical effects of interbody cage height on adjacent segments in patients with lumbar degeneration undergoing transforaminal lumbar interbody fusion (TLIF) surgery, so as to provide re...

    Authors: Xiao Lu, Dachuan Li, Hongli Wang, Xinlei Xia, Xiaosheng Ma, Feizhou Lv, Fei Zou and Jianyuan Jiang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:325
  12. Although arthroplasty provides satisfactory pain relief, functional improvement, and reduced flexion contracture in patients with hemophilia arthropathy, bleeding remains the primary problem associated with he...

    Authors: Shanyou Yuan, Lixia Song, Haoli Jiang, Jinghua Wang, Xianjia Ning and Wenxue Jiang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:324
  13. Intrathecal morphine (ITM) provides optimal postoperative analgesia in patients who are scheduled for total knee and hip operation with spinal anaesthesia. However, the ideal dose at which maximal analgesic ef...

    Authors: Mpumelelo Sibanyoni, Ntombiyethu Biyase and Palesa Motshabi Chakane
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:323
  14. There is still a lack of remarkable consensus regarding the clinical efficacy of the application of fibular strut augmentation (FSA) combined with a locking plate for proximal humeral fractures. A systematic r...

    Authors: Wei Nie, Zhaojun Wang, Fei Gu, Shizhuang Xu, Yang Yue, Anze Shao and Kefu Sun
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:322
  15. The objective of this study was to evaluate the clinical and radiological results of the treatment of aseptic nonunion of the tibia by plating and bone grafting.

    Authors: Khalid Chmali, Mohammed ElIdrissi, Hatim Abid, Abdelhalim ElIbrahimi, Mohamed Berraho and Abdelmajid ELMrini
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:321
  16. In this paper, the in-vivo healing of critical-sized bony defects by cell-free and stem cell-seeded 3D-printed PLA scaffolds was studied in rat calvaria bone. The scaffolds were implanted in the provided defec...

    Authors: Marjan Bahraminasab, Athar Talebi, Nesa Doostmohammadi, Samaneh Arab, Ali Ghanbari and Sam Zarbakhsh
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:320
  17. This Bayesian network meta-analysis investigated the available randomized control trials (RCTs) to point out which acupuncture protocol is the most effective for chronic aspecific low back pain (LBP). Efficacy...

    Authors: Alice Baroncini, Nicola Maffulli, Jörg Eschweiler, Friedrich Molsberger, Alexandra Klimuch and Filippo Migliorini
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:319
  18. Hip arthroscopy for treatment of femoroacetabular impingement (FAI) has developed rapidly and has been shown to significantly decrease pain and improve hip function. However, the relationship between hip capsu...

    Authors: Guanying Gao, Chenbo Jiao, Jiayang Liu, Chang Zhou, Yuhao Liu, Yingfang Ao and Yan Xu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:316
  19. Abnormal epiphyseal growth plate development of the proximal tibia in hemophilia patients leads to notable morphological changes in the mature knee joint. This study aimed to compare the morphological characte...

    Authors: Ru Feng, Qigang Zhong, Liujie Zheng, Houlong Ye, Dasheng Luo, Mingyang Ding, Nanyu Pang, Jiale Li and Yunfeng Yao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:315
  20. Diabetic osteoporosis (DOP) is one of the chronic complications of diabetes mellitus, but without a standardized treatment plan till now. Liuwei Dihuang pill (LDP) has gradually exerted a remarkable effect on ...

    Authors: Zhaoqi Lu, Minling Huang, Haixiong Lin, Gaoxiang Wang and Huilin Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:314
  21. Minimally invasive surgery for pelvic fracture using anterior ring internal fixator system is increasing gradually, and the way to insert the fixation screws in the fixation system is the key technical points ...

    Authors: Lin Liu, Shicai Fan, Donggui Zeng, Hui Song, Letian Zeng, Xiangyuan Wen and Dadi Jin
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:312
  22. Some authors secured the membrane during matrix-induced autologous chondrocyte implantation (mACI) with fibrin glue or did not use a formal fixation. The real impact of fibrin glue addition on chondrocytes mig...

    Authors: Filippo Migliorini, Julia Prinz, Nicola Maffulli, Jörg Eschweiler, Christian Weber, Sophie Lecoutrier, Frank Hildebrand, Johannes Greven and Hanno Schenker
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:311
  23. In knee osteoarthritis, progressive degeneration of the articular cartilage surface produces disability and chronic pain. Intra-articular injections of stromal vascular fraction (SVF) could be an innovative ap...

    Authors: Cristian Aletto, Lorenzo Giordano, Marco Quaranta, Arnaldo Zara, Donato Notarfrancesco and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:310
  24. Early onset scoliosis (EOS) presents in patients younger than 10 years. Magnetically controlled growing rods (MCGR) were developed as an outpatient distraction system for EOS, allowing to avoid multiple surger...

    Authors: Filippo Migliorini, Wai On Chiu, Raffaele Scrofani, Wai Kwong Chiu, Alice Baroncini, Giorgio Iaconetta and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:309
  25. This systematic review investigated the efficacy and safety of surgical procedures augmented with cell therapies for chondral defects of the talus.

    Authors: Filippo Migliorini, Jörg Eschweiler, Christian Goetze, Torsten Pastor, Riccardo Giorgino, Frank Hildebrand and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:308
  26. Musculoskeletal ailments impact the lives of millions of people, and at times necessitate surgery followed by physiotherapy, drug treatments, or immobilization. Regenerative musculoskeletal medicine has underg...

    Authors: Adarsh Aratikatla, Nicola Maffulli, Hugo C. Rodriguez, Manu Gupta, Anish G. Potty, Saadiq F. El-Amin III and Ashim Gupta
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:307
  27. Due to the global COVID-19 pandemic, a ban on sports outside one’s home and a prohibition on travel between communities were imposed in spring 2020 in Tyrol, Austria. The aim of this study was to evaluate the ...

    Authors: Cornelia Ower, Kerstin Stock, Peter Kaiser, Hanno Ulmer, Rohit Arora and Matthias Haselbacher
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:306
  28. p16, p53, and proliferating cell nuclear antigen (pcna) genes play significant roles in many chromatin modifications and have been found to be highly expressed in a variety of tumor tissues. Therefore, they have ...

    Authors: Dechao Cai, Xiao Ma, Huihui Guo, Haotian Zhang, Ashuai Bian, Haoran Yu and Wendan Cheng
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:305
  29. Monteggia fractures and Monteggia-like lesions result after severe trauma and have high complication rates. Preliminary biomechanical studies suggested a correlation between ulnar fracture localization and cli...

    Authors: Eric Tille, L. Seidel, A. Schlüßler, Franziska Beyer, P. Kasten, O. Bota, A. Biewener and J. Nowotny
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:303
  30. At present, concomitant avascular necrosis (AVN) of femoral head and septic arthritis (SA) as a sequel of COVID-19 infection has yet not been documented. By large-scale use of life-saving corticosteroids (CS) ...

    Authors: Mohammad Vahedian Ardakani, Sara Parviz, Ehsan Ghadimi, Zahra Zamani, Mohammadreza Salehi, Mohammad Ayati Firoozabadi and S. M. Javad Mortazavi
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:302
  31. We undertook a comparative biomechanical study of type B1 fractures around femoral prostheses following cemented hip arthroplasty using the Ortho-Bridge System (OBS) and a locking compression plate/locking att...

    Authors: Yuntao Long, Yubin Qi, Guilai Zuo, Qingjie Zhang, Zhenlin Liu and Wen Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:301
  32. Fractures are the most common type of unintentional injury in children, with traumatic upper limb fractures accounting for approximately 80% of all childhood fractures. Many epidemiological investigations of u...

    Authors: Xin Qiu, Hansheng Deng, Zhenhui Zhao, Shuaidan Zeng, Yueping Zeng, Xinyu Wang, Hui Xu, Weiqing Li, Xiaodi Chen, Qisong Yang, Jiaxin Zhao, Shicheng Li, Zhiwen Cui, Yu Tang, Shuting Cui, Min Liu…
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:300
  33. Knee varus alignment represents a notorious cause of knee osteoarthritis. It can be caused by tibial deformity, combined tibial–femoral deformity and/or ligament imbalance. Understanding malalignment is crucia...

    Authors: Chiara Suardi, Davide Stimolo, Luigi Zanna, Christian Carulli, Matassi Fabrizio, Roberto Civinini and Matteo Innocenti
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:299
  34. The recombinant human bone morphogenetic protein (rhBMP) is a common graft substitute for treating cases of long bone nonunion. However, the feasibility of combining an autologous bone graft (ABG) with rhBMPs ...

    Authors: Chengxin Xie, Chenglong Wang, Yu Huang, Qinglong Li, Xin Tian, Wenwen Huang and Dong Yin
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:298
  35. During open-door laminoplasty, the position of the bone gutter is not fixed, and when the gutter migrates inward, the outer end of the titanium plate must be fixed on the lamina edge. It is unclear whether thi...

    Authors: Fa-jing Liu, Xiao-kun Ding, Yi Chai, Su-hong Qi and Peng-fei Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:297
  36. FAI (femoroacetabular impingement syndrome) is a common cause of hip pain, resulting in a decreased life quality. This study aims to compare the postoperative clinical outcome between arthroscopic surgery (AT)...

    Authors: Yanlin Zhu, Peng Su, Tianhao Xu, Lei Zhang and Weili Fu
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:296
  37. Ceramic bearings are used in total hip arthroplasty due to their excellent wear behaviour and biocompatibility. The major concern related to their use is material brittleness, which significantly impacts on th...

    Authors: Stefano Lucchini, Massimiliano Baleani, Federico Giardina, Andrea Martelli, Francesco Castagnini, Barbara Bordini and Francesco Traina
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:293
  38. The treatments for trochanteric fractures try to regain early mobility and limit morbidity and risk of reoperations. The most currently used dynamic hip screw (DHS) and the proximal femoral nail (PFN) are both...

    Authors: Hong Xu, Yang Liu, Erdem Aras Sezgin, Šarūnas Tarasevičius, Robin Christensen, Deepak Bushan Raina, Magnus Tägil and Lars Lidgren
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:292
  39. Distraction osteogenesis (DO), a kind of bone regenerative process, is not only extremely effective, but the osteogenesis rate is far beyond ordinary bone fracture (BF) healing. Exosomes (Exo) are thought to p...

    Authors: Tao Zhang, Weidong Jiang, Fengchun Liao, Peiqi Zhu, Lina Guo, Zhenchen Zhao, Yan Liu, Xuanping Huang and Nuo Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:291
  40. To investigate whether a cocktail therapy of dexamethasone, ropivacaine, dexmedetomidine, and vitamin B12 can achieve satisfactory pain relief and promote early functional recovery after PPECD.

    Authors: Peng Zou, Xiaoping Zhang, Rui Zhang, Jun-Song Yang, Lei Chu, Xiang-Fu Wang, Jian-Min Wei, Xin Chai, Yuan-Ting Zhao and Bo Liao
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:290
  41. This study aimed to explore whether 25% as the cutoff value of fat infiltration (FI) in multifidus (MF) could be a predictor of clinical outcomes of lumbar spinal stenosis (LSS) patients.

    Authors: Gengyu Han, Da Zou, Xinhang Li, Shuquan Zhang, Zhenxu Li, Siyu Zhou, Wei Li, Zhuoran Sun and Weishi Li
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:289
  42. Arthrometry has been introduced to evaluate the laxity of ankle joint in recent years. However, its role in the diagnosis of chronic ankle instability is still debatable. Therefore, we assessed the diagnostic ...

    Authors: Yungu Chen, Shengxuan Cao, Chen Wang, Xin Ma and Xu Wang
    Citation: Journal of Orthopaedic Surgery and Research 2022 17:287

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