Articles

Infrapatellar fat pad resection or preservation during total knee arthroplasty: a meta-analysis of randomized controlled trials

The infrapatellar fat pad (IPFP) or Hoffa’s fat pad is often resected during total knee arthroplasty in order to improve visibility. However, the management of the IPFP during total knee arthroplasty (TKA) is ...

Authors: Changjiao Sun, Xiaofei Zhang, Woo Guan Lee, Yan Tu, Huimin Li, Xu Cai and Huadong Yang

Evaluation of the bone morphology around four types of porous metal implants placed in distal femur of ovariectomized rats

To compare structural features of the femoral bone of ovariectomized and non-ovariectomized rats after implantation of porous materials (TANTALUM, CONCELOC, TTM, ATLANT).

Authors: Stanislav Bondarenko, Nataliya Ashukina, Valentyna Maltseva, Gennadiy Ivanov, Ahmed Amine Badnaoui and Ran Schwarzkopf

A surgical reduction technique for posterior cruciate ligament avulsion fracture in total knee arthroplasty: a comparison study

Posterior cruciate ligament (PCL) avulsion fracture of the tibia is an uncommon but serious complication during primary cruciate-retaining total knee arthroplasty (TKA). The first objective of this report was ...

Authors: Wei Lin, Jinghui Niu, Yike Dai, Huaxing Zhang, Jing Zhu and Fei Wang

Incidence of deep venous thrombosis (DVT) of the lower extremity in patients undergoing surgeries for ankle fractures

To investigate the incidence of postoperative deep venous thrombosis (DVP) in patients undergoing surgeries for ankle fractures and identify the associated risk factors.

Authors: Luo Zixuan, Wei Chen, Yansen Li, Xiaomeng Wang, Weili Zhang, Yanbin Zhu and Fengqi Zhang

Comparisons of the surface micromotions of cementless femoral prosthesis in the horizontal and vertical levels: a network analysis of biomechanical studies

Numerous quantitatively biomechanical studies measuring the fixation stability of femoral stem using micromotions at the bone-implant interfaces in different directions and levels remain inconclusive. This net...

Authors: Bomin Wang, Qinghu Li, Jinlei Dong, Dongsheng Zhou and Fanxiao Liu

A propensity score-matched analysis comparing outpatient and short-stay hospitalization to standard inpatient hospitalization following total ankle arthroplasty

Given the trend toward value-based care, there has been increased interest in minimizing hospital length of stay (LOS) after orthopedic procedures. Outpatient total ankle arthroplasty (TAA) has become more pop...

Authors: Mark A. Plantz, Alain E. Sherman and Anish R. Kadakia

Interlaminar stabilization offers greater biomechanical advantage compared to interspinous stabilization after lumbar decompression: a finite element analysis

Interlaminar stabilization and interspinous stabilization are two newer minimally invasive methods for lumbar spine stabilization, used frequently in conjunction with lumbar decompression to treat lumbar steno...

Authors: Teng Lu and Yi Lu

Evaluation of risk factors of vertebral fracture in Japanese female patients with glucocorticoid-induced osteoporosis

Glucocorticoid-induced osteoporosis and vertebral fracture are common complications in patients on glucocorticoid treatment for rheumatological diseases. The present study aimed to identify the risk factors of...

Authors: Yu Mori, Takuya Izumiyama, Kazuyoshi Baba, Naoko Mori, Hiroshi Fujii, Tomonori Ishii and Eiji Itoi

Clinical features and treatment of “Non-dislocated hyperextension tibial plateau fracture”

To explore the epidemiological characteristics, clinical characteristics, treatment strategies, and clinical results of non-dislocated hyperextension tibial plateau fracture.

Authors: Jiang Liangjun, Zheng Qiang, Pan Zhijun, Zhu Hanxiao and Chen Erman

Comparison of bone morphogenetic protein and autologous grafting in the treatment of limb long bone nonunion: a systematic review and meta-analysis

Bone morphogenetic proteins (BMPs) have strong bone induction properties and can promote healing of fractures and other defects. However, BMP treatment efficacy for long bone nonunion remains controversial. Th...

Authors: Yong-Qiang Zhou, Hong-Liang Tu, Yan-Ji Duan and Xiao Chen

Bone defect reconstruction with a novel biomaterial containing calcium phosphate and aluminum oxide reinforcement

Reconstruction of metaphyseal fractures represents a clinical challenge for orthopedic surgeons. Especially in osteoporotic bone, these fractures are frequently accompanied by osseous substance defects. In ord...

Authors: Alexander M. Keppler, Maximilian M. Saller, Alberton Paolo, Westphal Ines, Heidenau Frank, Schönitzer Veronika, Böcker Wolfgang, Kammerlander Christian, Schieker Matthias, Aszodi Attila and Neuerburg Carl

Biomechanical investigation of external fixators for the treatment of supracondylar humerus fractures

Authors: Christoph Castellani, Holger Till and Annelie-Martina Weinberg

COVID-19: not a contraindication for surgery in patients with proximal femur fragility fractures

Authors: Ilaria Morelli, Francesco Luceri, Riccardo Giorgino, Riccardo Accetta, Paolo Perazzo, Laura Mangiavini, Nicola Maffulli and Giuseppe M. Peretti

BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

Inflammation and apoptosis of chondrocytes are the pathological bases of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B ...

Authors: Zetao Ma, Deli Wang, Jian Weng, Sheng Zhang and Yuanshi Zhang

Surgical approach strategies for open reduction internal fixation of closed complex tibial Pilon fractures based on axial CT scans

To explore the application and clinical efficacy of surgical approach strategies in open reduction internal fixation of closed complex tibial Pilon fractures based on axial CT scans.

Authors: Yu Zhao, Jian Wu, Shijun Wei, Feng Xu, Changwang Kong, Xiaosong Zhi, Ming Huang and Xianhua Cai

Robot-assisted orthopedic surgery in the treatment of adult degenerative scoliosis: a preliminary clinical report

A single-institution, retrospective cohort study.

Authors: Xiuyuan Chen, Fan Feng, Xiaosheng Yu, Shurong Wang, Zhipeng Tu, Yingchao Han, Quan Li, Hao Chen, Zhi Chen, Lifeng Lao and Hongxing Shen

Estimation and influence of blood loss under endoscope for percutaneous endoscopic lumbar discectomy (PELD): a clinical observational study combined with in vitro experiment

The purpose of this study is to come up with new methods to quantitate the blood loss under endoscope and explore the influence of blood loss on percutaneous endoscopic lumbar discectomy (PELD).

Authors: Dong Dong Sun, Dan Lv, Wei Zhou Wu, He Fei Ren, Bu He Bao, Qun Liu and Ming Lin Sun

Effects of type 1 diabetes mellitus on lumbar disc degeneration: a retrospective study of 118 patients

The study aimed to investigate the correlation between type 1 diabetes (T1D) and lumbar disc degeneration (LDD).

Authors: Rui Chen, Xinjie Liang, Tianji Huang, Weiyang Zhong and Xiaoji Luo

COVID-19 strategy in organizing and planning orthopedic surgery in a major orthopedic referral center in an area of Italy severely affected by the pandemic: experience of the Department of Orthopedics, University of Padova

According to the required reorganization of all hospital activities, the recent COVID-19 pandemic had dramatic consequences on the orthopedic world. We think that informing the orthopedic community about the s...

Authors: P. Ruggieri, G. Trovarelli, A. Angelini, E. Pala, A. Berizzi and D. Donato

Influence of marital status on overall survival in adult patients with chordoma: a SEER-based study

As a rare primary bone tumor, no studies have reported the relationship between prognosis and marital status in patients with chordoma.

Authors: Chao Tang, Ruiliang Wang, Qingguo Lu, Shantao Wang, Gen Jia, Pengfei Cao, Xinfa Nie and Hailong Zhang

Quantitative assessment of neural elements in a rat model using nerve growth factor after remnant-preserving anterior cruciate ligament reconstruction: a histological and immunofluorescence pilot study

Immunofluorescence analyses of anterior cruciate ligament (ACL) allografts following remnant-preserving ACL reconstruction using Achilles tendon allografts have provided evidence for the presence of neural ele...

Authors: Sung Hyun Lee, Hyung Gyu Cho, Jin Soo Song, Keun Churl Chun and Churl Hong Chun

Evaluation of genetic susceptibility of common variants in SOX9 in patients with congenital talipes equinovarus in the Han Chinese population

Congenital talipes equinovarus (CTEV) is a common birth defect that causes severe deformities of one or both feet. Genetics have been proven to play a key role in the risk of CTEV. Our study aimed to evaluate ...

Authors: Jian Li, Zhi Wang, Dongxu Feng, Wei Wang and Weilou Feng

Astaxanthin alleviates spinal cord ischemia-reperfusion injury via activation of PI3K/Akt/GSK-3β pathway in rats

Ischemia-reperfusion injury of the spinal cord (SCII) often leads to unalterable neurological deficits, which may be associated with apoptosis induced by oxidative stress and inflammation. Astaxanthin (AST) is...

Authors: Jian Fu, Haibin Sun, Haofei Wei, Mingjie Dong, Yongzhe Zhang, Wei Xu, Yanwei Fang and Jianhui Zhao

Response to “Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement”

Authors: Giovanni Trisolino, Marta Favero, Dante Dallari, Enrico Tassinari, Francesco Traina, Miguel Otero, Steven R. Goldring, Mary B. Goldring, Chiara Carubbi, Roberta Ramonda, Stefano Stilli, Brunella Grigolo and Eleonora Olivotto

Surgical management of ulnar styloid fractures: comparison of fixation with anchor suture and tension band wire

Limited reference is available regarding surgical management in symptomatic ulnar styloid fractures with small bony avulsion. The study goal is to report the surgical outcomes using anchor suture fixation with...

Authors: Alvin Chao-Yu Chen, Yi-Hsuan Lin, Chun-Jui Weng and Chun-Ying Cheng

Accuracy and safety of C2 pedicle or pars screw placement: a systematic review and meta-analysis

Systematic review and meta-analysis.

Authors: Parisa Azimi, Taravat Yazdanian, Edward C. Benzel, Hossein Nayeb Aghaei, Shirzad Azhari, Sohrab Sadeghi and Ali Montazeri

Clubfoot treatment with Ponseti method—parental distress during plaster casting

Clubfoot is one of the most prevalent musculoskeletal congenital defects. Gold standard treatment of idiopathic clubfoot is the conservative Ponseti method, including the reduction of deformity with weekly ser...

Authors: Christian Walter, Saskia Sachsenmaier, Markus Wünschel, Martin Teufel and Marco Götze

Immunohistochemical analysis of sensory corpuscles in human transplants of the anterior cruciate ligament

Sensory nerve endings in ligaments play an important role for the proprioceptive function. Clinical trials show that the sense of body position does not fully recover in the knee joint after reconstructive sur...

Authors: D. Rebmann, H. O. Mayr, H. Schmal, S. Hernandez Latorre and A. Bernstein

Fasciotomy through multiple small skin incisions for the treatment of early acute osteofascial compartment syndrome in children

The purpose of the present study is to investigate the therapeutic effect of fasciotomy through multiple small skin incisions for the treatment of early osteofascial compartment syndrome in children.

Authors: Xiaowei Yuan, Jun Wu, Xiangyang Qu, Ming Li, Linjun Jiang and Xing Liu

The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3

The pathophysiology of rheumatoid arthritis (RA) is characterized by excess production of pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6)...

Authors: Tomotake Kanai, Naoki Kondo, Masayasu Okada, Hiroshige Sano, Go Okumura, Yasufumi Kijima, Akira Ogose, Hiroyuki Kawashima and Naoto Endo

Outcome of osteofibrous dysplasia-like versus classic adamantinoma of long bones: a single-institution experience

The clinical and molecular characteristics of osteofibrous dysplasia (OFD)-like adamantinoma (AD) differ from those of classic AD. Most reports about OFD-like AD are case reports or small case series. More cas...

Authors: Zhiping Deng, Lihua Gong, Qing Zhang, Lin Hao, Yi Ding and Xiaohui Niu

Risk factors for iliopsoas impingement after total hip arthroplasty using a collared femoral prosthesis

The relationship between collar design of a femoral component and iliopsoas impingement (IPI) after total hip arthroplasty (THA) is still underrecognized. The purpose of our study was to determine the possible...

Authors: Jiandi Qiu, Xiurong Ke, Shanxi Chen, Liben Zhao, Fanghui Wu, Guojing Yang and Lei Zhang

Nociceptin is present in synovial fluid of patients undergoing total knee arthroplasty

Osteoarthritis is a mechanical abnormality characterized by chronic joint pain associated with degeneration of the articular cartilage, synovitis, and local inflammation, leading to loss of function and pain. ...

Authors: Thomas A. Verbeek, Nancy Ruth Jarbadan, Charles Davis and Julia Caldwell

D-dimer in the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis

D-dimer, a coagulation-related indicator, has recently been used as a tool for the diagnosis of periprosthetic joint infection (PJI), but its reliability is uncertain. The purpose of this systematic review and...

Authors: Guangxu Lu, Tong Li, Haoqi Ye, Shujin Liu, Peng Zhang and Wenliang Wang

Study on the outcome of patients with aseptic femoral head necrosis treated with percutaneous multiple small-diameter drilling core decompression: a retrospective cohort study based on magnetic resonance imaging and equivalent sphere model analysis

Aseptic necrosis of the femoral head (ANFH) has a high incidence in the community and causes substantial problems with health as well as economic and social stress. Core decompression is the most commonly used...

Authors: Yang Tan, Hangyuan He, Zihao Wan, Jun Qin, Yinxian Wen, Zhengqi Pan, Hua Wang and Liaobin Chen

Nonoperative treatment versus volar locking plate fixation for elderly patients with distal radial fracture: a systematic review and meta-analysis

This systematic review and meta-analysis assessed the role of nonoperative treatment and volar locking plate (VLP) fixation in elderly patients with distal radial fracture.

Authors: Qiang Li, Chao Ke, Shuang Han, Xin Xu, Yu-Xuan Cong, Kun Shang, Ji-Dong Liang and Bin-Fei Zhang

Anterior cervical discectomy and fusion with recombinant human bone morphogenetic protein-2-adsorbed β-tricalcium phosphate granules: a preliminary report

Anterior cervical discectomy and fusion (ACDF) is an alternative to conservative therapy in the treatment of cervical spondylopathy. This study evaluated the clinical outcome of ACDF with BMP-2-adsorbed β-tric...

Authors: Ze Wang, Soomin Lee, Zheng Li, Shuhao Liu, Qintong Xu, Jian Zhang and Dehua Meng

Three-dimensional-printed customized prosthesis for pubic defect: prosthesis design and surgical techniques

This study is to describe the detailed design and surgical techniques of three-dimensional (3D)-printed customized prosthesis for pubic bone defect.

Authors: Yuqi Zhang, Li Min, Minxun Lu, Jie Wang, Yitian Wang, Yi Luo, Yong Zhou, Hong Duan and Chongqi Tu

Anatomical conditions and patient-specific locked navigation templates for transverse sacroiliac screw placement: a retrospective study

To analyse the anatomical conditions of transverse sacroiliac screw (TSS) about the S1 and S2 segments in order to develop and validate a locked navigational template for TSS placement.

Authors: Chao Wu, Jiayan Deng, Jian Pan, Tao Li, Lun Tan and Dechao Yuan

Effect of unilateral pulsed jet lavage prior to vertebroplasty on the intravertebral pressure and cement distribution

Percutaneous vertebroplasty is the most common treatment for osteoporotic vertebral compression fracture. However, the morbidity of vertebroplasty-related complications, such as cement leakage, remains high. W...

Authors: Jun Yan, Qiaohui Liu, Yanping Zheng, Ziqun Liu, Xinyu Liu, Xun Guo, Penghui Liu, Peng Chen, Suomao Yuan, Yonghao Tian and Wanlong Xu

Intraoperative ultrasonography assistance for minimally invasive repair of the acute Achilles tendon rupture

Minimally invasive repair is a better option for Achilles tendon rupture with low re-rupture and wound-related complications than conservative treatment or traditional open repair. The major problem is sural n...

Authors: Yang Yongliang, Jia Honglei, Zhang Wupeng, Xu Shihong, Wang Fu, Wang Bomin, Li Qinghu, Wang Yonghui and Han Shumei

Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis: a single-center prospective randomized controlled study with a 1-year follow up

Osteoarthritis is the most prevalent type of arthritis, which significantly impacts the patient’s mobility and quality of life. Pharmacological treatments for osteoarthritis, such as corticosteroids, produce a...

Authors: Andrejs Elksniņš-Finogejevs, Luis Vidal and Andrejs Peredistijs

A comparison of EFECE systems with tension band wiring for patella fracture fixation in cadavers

EFECE systems are newly defined internal fixation systems, which are suitable for patella fracture fixation. The aim of this study was to compare the fixation strength of EFECE Systems with tension band wiring...

Authors: Emre Karadeniz and Elif Nedret Keskinoz

MiR-708 inhibits MC3T3-E1 cells against H₂O₂-induced apoptosis through targeting PTEN

The dysregulation of proliferation and apoptosis plays a significant role in the pathogenesis of postmenopausal osteoporosis (PO). MicroRNAs play an important role in regulating apoptosis of MC3T3-E1 cells. Ho...

Authors: Wei Zhang, Sheng-Yu Cui, Hong Yi, Xin-Hui Zhu, Wei Liu and You-Jia Xu

MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7

To explore the effect of miR-920 on osteogenic differentiation of human bone mesenchymal stem cells (hBMSCs) and the possible mechanism.

Authors: Jun-pu Zha, Xiao-qing Wang and Jun Di

Pilot investigation into osteotome hard surface coating and cutting-edge degradation

Osteotomes are bone cutting tools commonly reused in orthopedic surgical procedures. Despite undergoing rigorous cleaning, visual inspection, and sterilization procedures between every use, the condition of th...

Authors: David E. White, Jim Bartley, Christopher Whittington, Lorenzo M. G. Garcia, Kaushik Chand and Celine Turangi

Finite element analysis of the initial stability of arthroscopic ankle arthrodesis with three-screw fixation: posteromedial versus posterolateral home-run screw

Arthroscopic ankle arthrodesis (AAA) is a standard surgical method for the treatment of advanced traumatic ankle arthritis and has become more popular due to its advantages. To fix the tibiotalar joint, the us...

Authors: Sen Wang, Jian Yu, Xin Ma, Dahang Zhao, Xiang Geng, Jiazhang Huang and Xu Wang

Meta-analysis in periprosthetic joint infection: a global bibliometric analysis

Periprosthetic joint infection (PJI) is the most serious complication of joint replacement surgery. Further comorbidities include bedsore, deep vein thrombosis, reinfection, or even death. An increasing number...

Authors: Cheng Li, Christina Ojeda-Thies, Chi Xu and Andrej Trampuz

Clinical observation of two bone cement distribution modes of percutaneous vertebroplasty in the treatment of thoracolumbar Kümmell’s disease

In recent years, percutaneous vertebroplasty (PVP) has provided a new option for the treatment of Kümmell’s disease (KD). This retrospective study aimed to investigate the differences in clinical characteristi...

Authors: Ji-Bin Chen, Ya-Ping Xiao, Dong Chen, Jian-Zhong Chang and Te Li

Single versus dual orthogonal plating for comminuted midshaft clavicle fractures: a biomechanics study

Dual orthogonal plating of clavicle fractures may provide greater stiffness and strength than unilateral plate constructs and allow the use of lower-profile plates. We aim to biomechanically compare three clav...

Authors: Glenn N. Boyce, Andrew J. Philpott, David C. Ackland and Eugene T. Ek