Articles

The potent anti-inflammatory effect of Guilu Erxian Glue extracts remedy joint pain and ameliorate the progression of osteoarthritis in mice

Osteoarthritis (OA) is a slow progressing, degenerative disorder of the synovial joints. Guilu Erxian Glue (GEG) is a multi-component Chinese herbal remedy with long-lasting favorable effects on several condit...

Authors: Yen-Jung Chou, Jiunn-Jye Chuu, Yi-Jen Peng, Yu-Hsuan Cheng, Chin-Hsien Chang, Chieh-Min Chang and Hsia-Wei Liu

Arthroscopic removal of loose bodies using the accessory portals in the difficult locations of the knee: a case series and technical note

It is often technically demanding to find and remove loose bodies in several difficult locations like the popliteus hiatus and posterior compartment arthroscopically. We aim to present the technical aspects of...

Authors: Biao Chen, Liaobin Chen, Haitao Chen, Xu Yang, Kai Tie and Hua Wang

Bilateral dual iliac screws in spinal deformity correction surgery

Surgery for adult spinal deformity requires optimal patient-specific spino-pelvic-lower extremity alignment. Distal fixation in thoracolumbar spinal deformity surgery is crucial when arthrodesis to the sacrum ...

Authors: Shigeto Ebata, Tetsuro Ohba, Hiroki Oba and Hirotaka Haro

Using anatomical landmarks to calculate the normal joint line position in Chinese people: an observational study

Restoring the normal joint line (JL) is an important goal to achieve in total knee arthroplasty (TKA). We intended to study the veracity of several landmarks used to level the normal JL in Chinese people.

Authors: Aoyuan Fan, Tianyang Xu, Xifan Li, Lei Li, Lin Fan, Dong Yang and Guodong Li

Effect of low-intensity long-duration ultrasound on the symptomatic relief of knee osteoarthritis: a randomized, placebo-controlled double-blind study

Wearable long-duration low-intensity ultrasound is an emerging non-invasive and non-narcotic therapy for the daily treatment of musculoskeletal pain. The aim of this randomized, double-blind, placebo-controlle...

Authors: David O Draper, Dominic Klyve, Ralph Ortiz and Thomas M Best

Ultrasonography, an operator-dependent modality versus dual-energy computed tomography (DECT) in the detection of chondrocalcinosis: with regard to Tanikawa et al.’s study

Authors: Angel Checa

Pressure distributions inside intervertebral discs under unilateral pedicle screw fixation in a porcine spine model

Little data are available regarding the effects of pedicle screws on the intervertebral disc stress for different spinal segments. The aim of this study was to analyze the intervertebral disc stress in respons...

Authors: Zhao Meng, Chen Wang, Li-Jun Tian, Xue-Jun Zhang, Dong Guo and Yan Zou

Reverse shoulder arthroplasty vs BIO-RSA: clinical and radiographic outcomes at short term follow-up

Bony increased-offset reverse shoulder arthroplasty (BIO-RSA) may address issues such as inferior scapular notching, prosthetic instability and limited postoperative shoulder rotation; all of which have been r...

Authors: Nathan Kirzner, Eldho Paul and Ash Moaveni

Preoperative dual-energy X-ray absorptiometry and FRAX in patients with lumbar spinal stenosis

Osteoporosis implies an increased risk of complications after orthopedic surgery. For the mostly elderly group of patients undergoing lumbar spinal stenosis surgery (LSS), it is important to include skeletal h...

Authors: Camilla Bergh, Ann-Charlott Söderpalm and Helena Brisby

Exploratory analysis of predictors of revision surgery for proximal junctional kyphosis or additional postoperative vertebral fracture following adult spinal deformity surgery in elderly patients: a retrospective cohort study

Proximal junctional kyphosis (PJK) following adult spinal deformity (ASD) surgery in elderly patients is markedly influenced by osteoporosis causing additional vertebral fracture and loosening of pedicle screw...

Authors: Hiroshi Uei, Yasuaki Tokuhashi, Masafumi Maseda, Masahiro Nakahashi, Hirokatsu Sawada, Koji Matsumoto and Hiroyuki Miyakata

Efficacy of intravenous acetaminophen in multimodal management for pain relief following total knee arthroplasty: a meta-analysis

The efficacy of intravenous acetaminophen in multimodal pain management in patients undergoing total knee arthroplasty (TKA) is controversial. The purpose of this meta-analysis was to compare the efficacy of i...

Authors: Song-bo Shi, Xing-bo Wang, Jian-min Song, Shi-fang Guo, Zhi-xin Chen and Yin Wang

Effect of pedicle screw augmentation with a self-curing elastomeric material under cranio-caudal cyclic loading—a cadaveric biomechanical study

Pedicle screws can be augmented with polymethylmethacrylate (PMMA) cement through cannulated and fenestrated pedicle screws to improve screw anchorage. To overcome the drawbacks of PMMA, a modified augmentatio...

Authors: Werner Schmoelz, Alexander Keiler, Marko Konschake, Richard A Lindtner and Alessandro Gasbarrini

Chemokine analysis as a novel diagnostic modality in the early prediction of the outcome of non-union therapy: a matched pair analysis

Despite the regenerative capability of skeletal tissue fracture, non-union is common. Treatment of non-unions remains challenging, and early determination of the outcome is impossible. Chemokines play an impor...

Authors: Patrick Haubruck, Anja Solte, Raban Heller, Volker Daniel, Michael Tanner, Arash Moghaddam, Gerhard Schmidmaier and Christian Fischer

High failure rate of proximal femoral locking plates in fixation of trochanteric fractures

The aim of this study was to report our previous results of treatments for trochanteric fractures with proximal femoral locking plates (PFLP) and to analyze the underlying mechanisms and possible risk factors ...

Authors: Shuangjian He, Bin Yan, Jian Zhu, Xiaoyi Huang and Jianning Zhao

Tibiofemoral joint contact area and stress after single-bundle anterior cruciate ligament reconstruction with transtibial versus anteromedial portal drilling techniques

During single-bundle ACLR, femoral tunnel location plays an important role in restoring the intact knee mechanisms, whereas malplacement of the tunnel was cited as the most common cause of knee instability. Th...

Authors: Chunhui Liu, Yingpeng Wang, Zhongli Li, Ji Li, Hao Zhang, Yangmu Fu and Kuan Zhang

Psychological symptoms and the MCID of the DASH score in shoulder surgery

Psychological symptoms are frequently present in patients scheduled for shoulder surgery. The perception of functional disability, activity level and pain in the shoulder is negatively influenced by psychologi...

Authors: Rinco C T Koorevaar, Ydo V Kleinlugtenbelt, Ellie B M Landman, Esther van ‘t Riet and Sjoerd K Bulstra

Adjacent segment degeneration or disease after cervical total disc replacement: a meta-analysis of randomized controlled trials

Anterior cervical discectomy and fusion (ACDF) has been widely used in cervical spondylosis, but adjacent segment degeneration/disease (ASD) was inevitable. Cervical total disc replacement (TDR) could reduce t...

Authors: Shuai Xu, Yan Liang, Zhenqi Zhu, Yalong Qian and Haiying Liu

Impact of graft and tunnel orientation on patient-reported outcome in anterior cruciate ligament reconstruction using bone-patellar tendon-bone autografts

The optimal positioning of anterior cruciate ligament graft is still controversially discussed. We therefore wanted to determine the tunnel-to-joint (TJA), tunnel-to-shaft (TSA), and graft-tunnel divergence an...

Authors: Christoph J. Laux, Erika J. Ulbrich, Gustav Andreisek, Magda Marcon, Michael A. Fischer, Tarun Mehra and Bernhard D. Ciritsis

Extensile lateral versus sinus tarsi approach for displaced, intra-articular calcaneal fractures: a meta-analysis

Operative management of displaced, intra-articular calcaneal fractures is associated with improved functional outcomes but associated with frequent complications due to poor soft tissue healing. The use of a m...

Authors: Cyrus Rashid Mehta, Vincent V. G. An, Kevin Phan, Brahman Sivakumar, Andrew J. Kanawati and Mayuran Suthersan

Comparative effectiveness and safety of tranexamic acid plus diluted epinephrine to control blood loss during total hip arthroplasty: a meta-analysis

The standard protocol to achieve haemostasis during total hip arthroplasty (THA) is uncertain. Tranexamic acid plus diluted epinephrine (DEP) and tranexamic acid (TXA) alone are the two most common alternative...

Authors: Zhao Wang and Hao-jie Zhang

Posterior hemivertebra resection with unilateral instrumented fusion in children less than 10 years old: preliminary results at minimum 5-year follow-up

The main treatment for congenital hemivertebra is posterior hemivertebrectomy with bilateral transpedicular fixation. To date, studies describing posterior unilateral fusion are few, especially in younger chil...

Authors: Xuhong Xue and Sheng Zhao

Is minimally invasive superior than open transforaminal lumbar interbody fusion for single-level degenerative lumbar diseases: a meta-analysis

In recent years, the minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) is increasingly used to manage the lumbar degenerative disease. However, whether MI-TLIF was superior than open transfor...

Authors: Aimin Li, Xiang Li and Yang Zhong

The factors of deterioration in long-term clinical course of lumbar spinal canal stenosis after successful conservative treatment

The treatment of lumbar spinal canal stenosis (LSS) depends on symptom severity. In the absence of severe symptoms such as severe motor disturbances or bowel and/or urinary dysfunction, conservative treatment ...

Authors: Masanori Tsubosaka, Shuichi Kaneyama, Tomonori Yano, Koichi Kasahara, Aritetsu Kanemura, Masato Takabatake, Hiroaki Hirata and Masatoshi Sumi

Effect of lycopene on titanium implant osseointegration in ovariectomized rats

Lycopene prevents bone loss in osteopenic models. However, the role of lycopene in the success rate of dental implants under osteopenic conditions remains unknown. The aim of this study was to evaluate whether...

Authors: Xiaojie Li, Wenli Xue, Yong Cao, Yanming Long and Mengsheng Xie

Minimally invasive treatment for anterior pelvic ring injuries with modified pedicle screw-rod fixation: a retrospective study

Pelvic ring injuries constitute only 2 to 8% of all fractures; however, they occur in 20% of polytrauma patients. High-energy pelvic fractures often result in mechanical instability of the pelvic ring. Success...

Authors: Chun-Chi Hung, Jia-Lin Wu, Yuan-Ta Li, Yung-Wen Cheng, Chia-Chun Wu, Hsain-Chung Shen and Tsu-Te Yeh

Modified triple pelvic osteotomy for adult symptomatic acetabular dysplasia: clinical and radiographic results at midterm follow-up

Acetabular dysplasia is the most common cause of secondary arthritis of the hip joint. Achieving maximum restoration of the acetabular coverage and medialization of the femoral head remains difficult with the ...

Authors: Jiajun Wu, Yang Yang, Xiuhui Wang, Xiaoxiao Zhou and Changqing Zhang

One-year mortality in displaced intracapsular hip fractures and associated risk: a report of Chinese-based fragility fracture registry

The purpose of this registry-based retrospective study was to investigate the risk factors related to one-year mortality in displaced intracapsular fragility hip fracture patients.

Authors: Simon Kwoon-Ho Chow, Jiang-hui Qin, Ronald Man-Yeung Wong, Wai-Fan Yuen, Wai-Kit Ngai, Ning Tang, Chor-Yin Lam, Tak-Wing Lau, Kin-Bong Lee, Kwai Ming Siu, Sze-Hung Wong, Tracy Y. Zhu, Wing-Hoi Cheung and Kwok-Sui Leung

How do we deliver our findings? Analysis of podium presentations at shoulder meetings

The aim of the present study was to evaluate the time structure of oral presentations delivered at three shoulder congresses: shoulder sessions at the American Academy of Orthopaedic Surgeons (AAOS) Meeting, E...

Authors: Joan Miquel, Fernando Santana, Albert Barrera and Carlos Torrens

Combined detection of COMP and CS846 biomarkers in experimental rat osteoarthritis: a potential approach for assessment and diagnosis of osteoarthritis

To comprehensively evaluate the diagnostic value of serum cartilage oligomeric matrix protein (COMP) and chondroitin sulfate 846 epitope (CS846) biomarkers in osteoarthritis (OA), longitudinal and combined mea...

Authors: Tianwen Ma, Zhiheng Zhang, Xiaopeng Song, Hui Bai, Yue Li, Xinran Li, Jinghua Zhao, Yuanqiang Ma and Li Gao

Remnant preservation technique versus standard technique for anterior cruciate ligament reconstruction: a meta-analysis of randomized controlled trials

This meta-analysis was performed to compare the clinical outcomes of primary anterior cruciate ligament (ACL) reconstruction using the ACL remnant preservation technique versus the standard technique.

Authors: Hong-De Wang, Fu-Shun Wang, Shi-Jun Gao and Ying-Ze Zhang

Association between SMAD3 gene polymorphisms and osteoarthritis risk: a systematic review and meta-analysis

Several studies have been performed to investigate the association between SMAD3 gene polymorphism and osteoarthritis (OA), but the results were inconclusive. This study aims to determine whether SMAD3 polymor...

Authors: Jian-qiao Hong, Yang-xin Wang, Si-hao Li, Guang-yao Jiang, Bin Hu, Yu-te Yang, Jia-hong Meng and Shi-gui Yan

The effect of intensive exercise program and kinesiotaping following total knee arthroplasty on functional recovery of patients

Total knee arthroplasty (TKA) is a gold standard for terminal term gonarthrosis patients in order to diminish pain, correct deformities, and regain stability. Postoperative functional recovery of patients depe...

Authors: Birhan Oktas and Ozge Vergili

A systematic review and meta-analysis of direct anterior approach versus posterior approach in total hip arthroplasty

This meta-analysis aimed to evaluate the postoperative clinical outcomes and safety of the direct anterior approach (DAA) versus posterior approach (PA) in total hip arthroplasty (THA).

Authors: Zhao Wang, Jing-zhao Hou, Can-hua Wu, Yue-jiang Zhou, Xiao-ming Gu, Hai-hong Wang, Wu Feng, Yan-xiao Cheng, Xia Sheng and Hong-wei Bao

A novel scoring system to guide prognosis in patients with pathological fractures

The most appropriate treatment of pathological fractures from metastatic disease depends on several factors, one of the most important being predicted life expectancy. The aim of this study was to identify the...

Authors: Xiang Salim, Peter D’Alessandro, James Little, Kulvir Mudhar, Kevin Murray, Richard Carey Smith and Piers Yates

An evaluation of anesthetic fade in motor evoked potential monitoring in spinal deformity surgeries

Intraoperative neuromonitoring using motor evoked potentials (MEP) satisfactorily detects motor tract integrity changes during spinal surgery. However, monitoring is affected by “anesthetic fade,” in which the...

Authors: Ryo Ugawa, Tomoyuki Takigawa, Hiroko Shimomiya, Takuma Ohnishi, Yuri Kurokawa, Yoshiaki Oda, Yasuyuki Shiozaki, Haruo Misawa, Masato Tanaka and Toshifumi Ozaki

Efficacy of K-wire tension band fixation compared with other alternatives for patella fractures: a meta-analysis

To compare the efficacy and safety of K-wire tension band fixation (KTB) with other alternative approaches (cannulated screws, cable pin, and ring pin) for treatment of patella fractures by performing a meta-a...

Authors: Yinwang Zhang, Zhen Xu, Wuxue Zhong, Fuhai Liu and Jie Tang

Effects of bisphosphonates in preventing periprosthetic bone loss following total hip arthroplasty: a systematic review and meta-analysis

Periprosthetic bone loss following total hip arthroplasty (THA) was a well-known phenomenon. This systematic review was to assess the effectiveness of bisphosphonates (BPs) for decreasing periprosthetic bone r...

Authors: Jialing Shi, Guang Liang, Rongzhi Huang, Liang Liao and Danlu Qin

The distal femur is a reliable guide for tibial plateau fracture reduction: a study of measurements on 3D CT scans in 84 healthy knees

Limited data have been published regarding the typical coronal dimensions of the femur and tibia and how they relate to each other. This can be used to aid in judging optimal operative reduction of tibial plat...

Authors: Sorawut Thamyongkit, Laura M. Fayad, Lynne C. Jones, Erik A. Hasenboehler, Norachart Sirisreetreerux and Babar Shafiq

Measurement of scoliosis Cobb angle by end vertebra tilt angle method

Scoliosis is a common deformity, and its severity is usually assessed by measuring the Cobb angle on the spinal X-ray film. The measurement of the Cobb angle is an important basis for selecting therapeutic met...

Authors: Jing Wang, Jin Zhang, Rui Xu, Tie Ge Chen, Kai Sheng Zhou and Hai Hong Zhang

The early diagnostic value of serum neopterin and cartilage oligomeric matrix protein for osteoarticular changes among brucellosis patients at an early period

Brucellosis is an important public health problem in China. Brucellosis can cause many osteoarticular changes, especially chronic brucellosis. Brucellosis presents various diagnostic difficulties because it mi...

Authors: Zhi-jun Zhao, Qiang Li, Li Ma, Ji-quan Li and Li-qing Xu

Coatings as the useful drug delivery system for the prevention of implant-related infections

Implant-related infections (IRIs) which led to a large amount of medical expenditure were caused by bacteria and fungi that involve the implants in the operation or in ward. Traditional treatments of IRIs were...

Authors: Chenhao Pan, Zubin Zhou and Xiaowei Yu

A new classification and its value evaluation for intermediate column fractures of the distal radius

Intermediate column fractures of the distal radius (ICF) are fractures only or mainly limited to the lunate fossa of the distal radius. There are no classification systems and its value evaluation for ICF in t...

Authors: Ying Yang, Qudong Yin, Dongchen Li, Yongjun Rui, Yongwei Wu, Yanping Ding and Yan Jiang

Osseointegrative effect of rhBMP-2 covalently bound on a titan-plasma-spray-surface after modification with chromosulfuric acid in a large animal bone gap-healing model with the Göttingen minipig

Bone morphogenetic proteins play an important role as osseointegrative factors. It is used widely in orthopedic research and surgery to enhance the osseointegrative potential of implants, e.g., in spinal fusio...

Authors: Manuel Lingner, Roland Seidling, Lars Johannes Lehmann, Eckhard Mauermann, Udo Obertacke and Markus Ludwig Rupert Schwarz

Comparison of tourniquet application only during cementation and long-duration tourniquet application in total knee arthroplasty: a meta-analysis

Tourniquet is widely used by orthopedic surgeons in total knee arthroplasty (TKA). However, there are still controversies on the optimal timing of tourniquet application. The aim of this meta-analysis was to c...

Authors: Cong Wang, Chenhe Zhou, Hao Qu, Shigui Yan and Zhijun Pan

Comparing the costs and outcomes of an integrated twin compression screw (ITCS) nail with standard of care using a single lag screw or a single helical blade cephalomedullary nail in patients with intertrochanteric hip fractures

Surgical treatment is the optimal strategy for managing intertrochanteric fractures as it allows for early rehabilitation and functional recovery. The purpose of the study was to assess the cost-effectiveness ...

Authors: Leo M. Nherera, Paul Trueman, Alan Horner, Alan J. Johnstone, Tracy J. Watson and Francis A. Fatoye

Clinical experience of debridement combined with resorbable bone graft substitute mixed with antibiotic in the treatment for infants with osteomyelitis

Osteomyelitis (OM) is an uncommon disease that originates from many different mechanisms in children. Treatment often involves a combination of surgical debridement combined and antibiotic therapy. The purpose...

Authors: Zhiqiang Zhang, Hao Li, Hai Li, Qing Fan, Xuan Yang, Pinquan Shen, Ting Chen, Qixun Cai, Jing Zhang and Ziming Zhang

M2 macrophages are closely associated with accelerated clavicle fracture healing in patients with traumatic brain injury: a retrospective cohort study

Mounting evidence indicate patients with traumatic brain injury (TBI) have an accelerated fracture healing. The healing process of bone fractures is greatly dependent on infiltrated macrophages. The macrophage...

Authors: Ran Zhang, Yi Liang and Shuxiang Wei

A novel revision surgery for treatment of cervical ossification of the posterior longitudinal ligament after initial posterior surgery: preliminary clinical investigation of anterior controllable antidisplacement and fusion

Cervical ossification of the posterior longitudinal ligament (OPLL) is a progressive disease. Posterior decompression surgery is reported to be an effective and comparatively safe procedure with few complicati...

Authors: Hai-Dong Li, Qiang-Hua Zhang, Shi-Tong Xing, Ji-Kang Min, Jian-Gang Shi and Xiong-Sheng Chen

The proper timing of second-stage revision in treating periprosthetic knee infection: reliable indicators and risk factors

Two-stage revision is the standard procedure for periprosthetic knee infection. But when to perform the second-stage is still under debate. We attempt to search the reliable indicators, risk factors, and prope...

Authors: Jun Fu, Ming Ni, Heng Li, Xiang Li, Wei Chai, Yonggang Zhou, Libo Hao and Jiying Chen

Clinical outcomes and repair integrity of arthroscopic rotator cuff repair using suture-bridge technique with or without medial tying: prospective comparative study

There have been few studies comparing clinical and radiological outcomes between the conventional and knotless suture-bridge techniques. The purpose of this study was to evaluate and compare the functional out...

Authors: Kyung Cheon Kim, Hyun Dae Shin, Woo-Yong Lee, Kyu-Woong Yeon and Sun-Cheol Han