Articles

Determining the stability of minimally displaced lateral humeral condyle fractures in children: ultrasound is better than arthrography

Authors: Andreas Rehm, Tamás Kobezda and Elizabeth Ashby

Application of an adjusted patient blood management protocol in patients undergoing elective total hip arthroplasty: towards a zero-percent transfusion rate in renal patients—results from an observational cohort study

Renal patients are at high risk of blood transfusion following major orthopaedic surgery. A variety of patient blood management (PBM) policies have been proposed to reduce the rate of transfusions. The aim of ...

Authors: Hervé Hourlier and Peter Fennema

Lumbar degenerative disease treated by percutaneous endoscopic transforaminal lumbar interbody fusion or minimally invasive surgery-transforaminal lumbar interbody fusion: a case-matched comparative study

This study aimed to evaluate the clinical efficacy and imaging results of percutaneous endoscopic transforaminal lumbar interbody fusion (PETLIF) through comparing it with minimally invasive surgery-transforam...

Authors: You-Di Xue, Wen-Bo Diao, Chao Ma and Jie Li

Development of a prognostic model for 1-year survival after fragile hip fracture in Chinese

No prognostic model for the survival of fragile hip fracture has been developed for Asians. The goal of this study was to develop a simple and practical prognostic model to predict survival within 1 year after...

Authors: Hairui Fu, Bin Liang, Wei Qin, Xiaoxiong Qiao and Qiang Liu

Artificial intelligence to diagnosis distal radius fracture using biplane plain X-rays

Although the automatic diagnosis of fractures using artificial intelligence (AI) has recently been reported to be more accurate than those by orthopedics specialists, big data with at least 1000 images or more...

Authors: Kunihiro Oka, Ryoya Shiode, Yuichi Yoshii, Hiroyuki Tanaka, Toru Iwahashi and Tsuyoshi Murase

Effects of endplate coverage and intervertebral height change on heterotopic ossification following cervical disc replacement

Heterotopic ossification (HO) is a common complication after cervical disc replacement (CDR). Biomechanical factors including endplate coverage and intervertebral disc height change may be related to HO format...

Authors: Yi-Wei Shen, Yi Yang, Hao Liu, Xin Rong, Chen Ding, Yang Meng, Bei-Yu Wang and Ying Hong

A new biomechanical classification system for split fractures of the humeral greater tuberosity: guidelines for surgical treatment

Split fractures of the humeral greater tuberosity (HGT) are common injuries. Although there are numerous surgical treatments for these fractures, no classification system combining clinical and biomechanical c...

Authors: Gang Liu, Xiaoguang Guo, Qian Zhao, Bo Qin, Junjie Lu, Dingsu Bao and Shijie Fu

In adults, early mobilization may be beneficial for distal radius fractures treated with open reduction and internal fixation: a systematic review and meta-analysis

It remains debatable if early mobilization (EM) yields a better clinical outcome than the late mobilization (LM) in adults with an acute and displaced distal radial fracture (DRF) of open reduction internal fi...

Authors: ZhiBo Deng, JiangPing Wu, KaiYing Tang, Han Shu, Ting Wang, FuBing Li and Mao Nie

Check-rein technique for Achilles tendon elongation following conservative management for acute Achilles tendon ruptures: a two-year prospective clinical study

Following conservative management for acute Achilles tendon (AT) ruptures, the tendon may heal in continuity, and some patients may present with an elongated Achilles tendon–gastrosoleus complex. This study in...

Authors: Nicola Maffulli, Francesco Oliva and Filippo Migliorini

Correction to: Management of chronic knee pain caused by postsurgical or posttraumatic neuroma of the infrapatellar branch of the saphenous nerve

Authors: G. J. Regev, D. Ben Shabat, M. Khashan, D. Ofir, K. Salame, Y. Shapira, R. Kedem, Z. Lidar and S. Rochkind

Efficacy of intra-articular ketorolac for pain control in arthroscopic surgeries: a systematic review and meta-analysis

The current systematic review and meta-analysis aimed to synthesize evidence on the efficacy of intra-articular ketorolac for patients undergoing arthroscopic surgeries.

Authors: Jingjing Yang, Bin Ni and Xiaoyan Fu

Computer-assisted cannulated screw internal fixation versus conventional cannulated screw internal fixation for femoral neck fractures: a systematic review and meta-analysis

To compare the effects between computer-assisted and traditional cannulated screw internal fixation on treating femoral neck fracture.

Authors: Qing-hao Cheng, Peng-biao Li, Ting-ting Lu, Shi-fang Guo, Wen-fei Di, Ke-hu Yang and Yao-wen Qian

Impact of intraoperative medial collateral ligament injury on outcomes after total knee arthroplasty: a meta-analysis and systematic review

As an uncommon but severe complication, medial collateral ligament (MCL) injury in total knee arthroplasty (TKA) may be significantly under-recognized. We aimed to determine whether MCL injury influences posto...

Authors: Jiahao Li, Zijian Yan, Yan Lv, Yijin Li, Pengcheng Ye, Peng Deng, Haitao Zhang, Jinlun Chen, Jie Li, Xinyu Qi, Jianchun Zeng, Yirong Zeng and Wenjun Feng

First dorsal metacarpal artery flap with dorsal digital nerve with or without dorsal branch of the proper digital nerve produces comparable short-term sensory outcomes

The first dorsal metacarpal artery flap, including dorsal digital nerves with or without dorsal branches of the proper digital nerves, can be used to reconstruct thumb pulp defects with good results. However, ...

Authors: Shi-Ming Feng, Jia-Ju Zhao, Filippo Migliorini, Nicola Maffulli and Wei Xu

Use of a suspended and straightened knee joint position when fixing steel plates can prevent the increase in postoperative posterior tibial slope after open‑wedge high tibial osteotomy

Posterior tibial slope (PTS) increases after medial open-wedge high tibial osteotomy (OWHTO) is challenging for patients. This study aims to determine whether use of a suspended and straightened knee joint pos...

Authors: Wenru Ma, Zengshuai Han, Shengnan Sun, Jinli Chen, Yi Zhang and Tengbo Yu

Chronic locked posterior gleno-humeral dislocation: technical note on fibular grafting for restoration of humeral head sphericity

Reconstruction of reverse Hill-Sachs defect using osteo-chondral allograft has the advantages of spherical re-contouring and provision of smooth biological articular surface of the reconstructed humeral head. ...

Authors: Amr Abdel-Mordy Kandeel

3D printing-assisted extended lateral approach for displaced intra-articular calcaneal fractures: a systematic review and meta-analysis

Three-dimensional (3D) printing technology has developed rapidly in orthopaedic surgery and effectively achieves precise and personalized surgery. The purpose of this meta-analysis was to assess the efficacy o...

Authors: Guang Shi, Wei Liu, Ying Shen and Xiyu Cai

Correlation between neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture: a meta-analysis

The neutrophil-to-lymphocyte ratio (NLR) is a crucial prognosis predictor following several major operations. However, the association between NLR and the outcome after hip fracture surgery is unclear. In this...

Authors: Yu-Hang Chen, Ching-Hsin Chou, Hsin-Hsien Su, Yu-Ting Tsai, Ming-Hsiu Chiang, Yi-Jie Kuo and Yu-Pin Chen

A 24-month retrospective update: follow-up hospitalization charges and readmissions in US lumbar fusion surgeries using a cellular bone allograft (CBA) versus recombinant human bone morphogenetic protein-2 (rhBMP-2)

The objectives of this study were to build upon previously-reported 12-month findings by retrospectively comparing 24-month follow-up hospitalization charges and potentially-relevant readmissions in US lumbar ...

Authors: Bradley Wetzell, Julie B. McLean, Kimberly Dorsch and Mark A. Moore

Ten-year survival of ceramic-on-ceramic total hip arthroplasty in patients younger than 60 years: a systematic review and meta-analysis

Total hip arthroplasty (THA) with ceramic-on-ceramic (CoC) was created to minimise wear debris and aseptic loosening. A decade ago, a meta-analysis showed a 10-year survival rate of just 89%. Based on the exce...

Authors: Ihab Ibraheam El-Desouky, Albaraa Hassan Helal and Ali Mohamed Reda Mansour

Arthroscopic triangular fibrocartilage complex reconstruction with free tendon graft for chronic distal radioulnar joint instability

Tears in the triangular fibrocartilage complex (TFCC) often manifest as ulnar wrist pain and limited wrist function. In chronic cases, the treatment of large tears with irreparable TFCC degeneration combined w...

Authors: Kuang-Ting Yeh and Jui-Tien Shih

The effect of self-reported knee instability on plantar pressure and postural sways in women with knee osteoarthritis

Giving way and knee instability are common problems in patients with knee osteoarthritis, disrupting the daily activities and balance of the affected individual. The present study aimed to evaluate the postura...

Authors: Liana Chaharmahali, Farzaneh Gandomi, Ali Yalfani and Alireza Fazaeli

Characteristics of intramedullary nail breakage in pertrochanteric femur fractures: a summary of 70 cases

To reveal noteworthy characteristics of intramedullary (IM) nail breakage in pertrochanteric femur fractures.

Authors: Pengfei Li, Zhishan Zhang, Fang Zhou, Yang Lv, Yan Guo and Yun Tian

The morphological mapping of lateral compression type 1 pelvic fracture and pelvic ring stability classification: a finite element analysis

This finite element analysis assessed lateral compression (LC-1) fracture stability using machine learning for morphological mapping and classification of pelvic ring stability.

Authors: Bin-Fei Zhang, Jun Wang, Yu-Min Zhang, Hui-Guang Cheng, Qian-Yue Cheng and Wen-Wen Cao

Biomechanical properties of a novel fixation system for intra-articular distal humerus fractures: a finite element analysis

The traditional strategy for fixing intra-articular distal humerus fractures is double plating placed in an orthogonal configuration, based on posterior approach. With a combined medial and lateral approach, a...

Authors: Lingpeng Kong, Yan Wang, Qingsen Lu, Yong Han and Fu Wang

Association of MIR17HG and MIR155HG gene variants with steroid-induced osteonecrosis of the femoral head in the population of northern China

Steroid-induced osteonecrosis of the femoral head (ONFH) is a disease of the bone. Metabolism and genetic factors are generally considered to play an important role. The purpose of this study was to investigat...

Authors: Tingting Liu, Yuju Cao, Changxu Han, Feimeng An, Tiantian Wang, Menghu Sun, Chao Ma, Qiumei Dong and Jianzhong Wang

Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis

Gabapentin and intravenous patient-controlled analgesia (PCA) can reduce postoperative pain scores, postoperative opioid use, and time to completing physical therapy compared to PCA alone after posterior spina...

Authors: Ying Li, Jennylee Swallow, Christopher Robbins, Michelle S. Caird, Aleda Leis and Rebecca A. Hong

Association between type of anesthesia and length of hospital stay in primary unilateral total knee arthroplasty patients: a single-center retrospective study

This study explored the risk factors influencing the length of hospital stay (LOS) and establish whether the type of anesthesia is independently associated with the LOS in patients after primary unilateral tot...

Authors: Xiaoqing Wang, He Li, Conghu Yuan and Hang Zhao

Robotic arm-assisted total knee arthroplasty improves preoperative planning and intraoperative decision-making

The reliability of robotic arm-assisted total knee arthroplasty (RA-TKA) has been previously reported. In this study, we evaluated the predictive accuracy of the RA-TKA system in determining the required bone ...

Authors: Xufeng Wan, Qiang Su, Duan Wang, Mingcheng Yuan, Yahao Lai, Hong Xu and Zongke Zhou

Global prevalence of osteoporosis among the world older adults: a comprehensive systematic review and meta-analysis

Osteoporosis is one of the most common bone system diseases that is associated with an increased risk of bone fractures and causes many complications for patients. With age, the prevalence of this disease incr...

Authors: Nader Salari, Niloofar Darvishi, Yalda Bartina, Mojdeh Larti, Aliakbar Kiaei, Mahvan Hemmati, Shamarina Shohaimi and Masoud Mohammadi

Improving postoperative radiographs for the parameter measurement of hexapod external fixator using an additional foot ring

It is challenging to determine the orthogonality of radiographs in daily clinical practice. The purpose of this study was to show the usefulness of an additional foot ring which might determine the orthogonali...

Authors: Yanshi Liu, Kai Liu, Feiyu Cai, Tao Zhang and Aihemaitijiang Yusufu

Expression of STOML2 promotes proliferation and glycolysis of multiple myeloma cells via upregulating PAI-1

This study aimed to investigate the effects of STOML2 and the relationship between STOML2 and PAI-1 in the development of multiple myeloma (MM).

Authors: Hongxia Zhang, Guangsheng Wu, Junjian Feng, Xiaohong Lu and Ping Liu

Revision arthroplasty after unicompartimental knee arthroplasty

Unicompartimental knee arthroplasty (UKA) is a promising and increasing application to treat unicompartimental knee osteoarthritis. However, revision arthroplasty numbers after UKA are unknown. Therefore, aim ...

Authors: Nike Walter, Johannes Weber, Maximilian Kerschbaum, Edmund Lau, Steven M. Kurtz, Volker Alt and Markus Rupp

FGD5-AS1 facilitates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting the miR-506-3p/BMP7 axis

Osteoporosis is a systemic disease characterized by impaired bone formation, increased bone resorption, and brittle bone fractures. The osteogenic differentiation of human bone marrow-derived mesenchymal stem ...

Authors: Jun Li, Xingbiao Wu, Yaohua Shi and Hong Zhao

Accuracy of one-dimensional templating on linear EOS radiography allows template-directed instrumentation in total knee arthroplasty

Templating for total knee arthroplasty (TKA) is routinely performed on two-dimensional standard X-ray images and allows template-directed instrumentation. To date, there is no report on one-dimensional (1D) an...

Authors: Michael Andreas Finsterwald, Salar Sobhi, Senthuren Isaac, Penelope Scott, Riaz J. K. Khan and Daniel P. Fick

Comparison of bone and articular cartilage changes in osteoarthritis: a micro-computed tomography and histological study of surgically and chemically induced osteoarthritic rabbit models

Osteoarthritis (OA) is a multifaceted condition that affects both the subchondral bones and the articular cartilage. Animal models are widely used as an effective supplement and simulation for human OA studies...

Authors: Sharifah Zakiah Syed Sulaiman, Wei Miao Tan, Rozanaliza Radzi, Intan Nur Fatiha Shafie, Mokrish Ajat, Rozaihan Mansor, Suhaila Mohamed, Angela Min Hwei Ng and Seng Fong Lau

Study on the relationship between the timing of conversion from external fixation to internal fixation and infection in the treatment of open fractures of extremities

To investigate the relationship between the infection rate and the timing of replacement of temporary external fixators with internal fixation, and the timing of immediate or delayed internal fixation after re...

Authors: Zelin Ye, Shanwen Zhao, Canjun Zeng, Ziheng Luo, Song Yuan and Runguang Li

Fixation failure in patients with traumatic diastasis of pubic symphysis: impact of loss of reduction on early functional outcomes

Failure of fixation (FF) in pubic symphysis diastasis (SD) ranges between 12 and 75%, though whether it influences functional outcomes is still debated. The objective of this study is to evaluate the impact of...

Authors: Claudio Rojas, Ernesto Ewertz and Jose Miguel Hormazábal

Total glycosides from Eucommia ulmoides seed promoted osteogenic differentiation of adipose-derived mesenchymal stem cells and bone formation in ovariectomized rats through regulating Notch signaling pathway

Osteoporosis (OP) is a well-known chronic degenerative disease, with impaired mesenchymal stem cells (MSCs) function and suppressed osteogenic differentiation. Total glycosides from Eucommia ulmoides seed (TGE...

Authors: Yu-hu Zhou and Qiang Xie

What is the effectiveness of radiofrequency ablation in the management of patients with spinal metastases? A systematic review and meta-analysis

Spinal metastases are indicative of progressive cancer which can lead to vertebral body fractures and spinal cord compression. Radiofrequency ablation (RFA) treatment is infrequently used in patients with refr...

Authors: Navanith Murali, Thomas Turmezei, Sumbal Bhatti, Puja Patel, Thomas Marshall and Toby Smith

LncRNA NONHSAT030515 promotes the chondrogenic differentiation of human adipose-derived stem cells via regulating the miR-490-5p/BMPR2 axis

Chondrogenic differentiation of human adipose-derived stem cells (hADSCs) is important for cartilage generation and degradation. LncRNAs play an essential role in stem cell differentiation. However, the role a...

Authors: Qinqin Yang, Jiajia Guo, Zhijing Ren, Bo Li, Haifeng Huang and Zhen Yang

Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits

Cartilage defect has a limited capacity to heal. In this context, we hypothesized that hyaluronic acid (HA) hydrogel encapsulated BMP-14-modified adipose-derived mesenchymal stem cells (ADSCs) could accelerate...

Authors: Hao Liu, Yongjun Rui, Jun Liu, Fandong Gao and Yesheng Jin

Assessment of sagittal spinopelvic alignment in asymptomatic Chinese juveniles and adolescents: a large cohort study and comparative meta-analysis

Retrospective study and comparative meta-analysis.

Authors: Canglong Hou, Kai Chen, Yu Chen, Tianjunke Zhou, Mingyuan Yang and Ming Li

Inverted reamer technique for bone grafting of the acetabulum: technical note

Socket fixation with bone grafting for dysplastic hips is technically demanding, and inadequate coverage of the socket may cause poor results in patients with severely dysplastic hips. An accurate technique to...

Authors: Yuki Okutani, Hiroshi Fujita, Hideto Harada, Masanao Kataoka, Yu Shimizu and Yoshiki Murotani

The risk factors and predictive nomogram of human albumin infusion during the perioperative period of posterior lumbar interbody fusion: a study based on 2015–2020 data from a local hospital

Perioperative hypoalbuminemia of the posterior lumbar interbody fusion (PLIF) can increase the risk of infection of the incision site, and it is challenging to accurately predict perioperative hypoproteinemia....

Authors: Bo Liu, Junpeng Pan, Hui Zong and Zhijie Wang

Protective effects of low-magnitude high-frequency vibration on high glucose-induced osteoblast dysfunction and bone loss in diabetic rats

Low-magnitude high-frequency vibration (LMHFV) has been reported to be capable of promoting osteoblast proliferation and differentiation. Reduced osteoblast activity and impaired bone formation were related to...

Authors: Zhaoyu Fu, Xu Huang, Pengcheng Zhou, Bo Wu, Long Cheng, Xinyu Wang and Dong Zhu

Association between serum estradiol level, sex hormone binding globulin level, and bone mineral density in middle-aged postmenopausal women

Changes in sex hormones are thought to play an important role in bone health in postmenopausal women. Our aim in this study was to evaluate the association between levels of estradiol (E2), which is the most p...

Authors: Zhongxin Zhu, Jin Zhao, Yanfei Fang and Rongwei Hua

Intra-articular injection of loaded sPL sustained-release microspheres inhibits osteoarthritis and promotes cartilaginous repairs

Osteoarthritis is a chronic inflammatory disease of the joints associated with significant morbidity and lower quality of life. Current treatment strategies focus on reducing cartilage degeneration but fail to...

Authors: Jiyou Li, Ning Liu, Zhipeng Huang, Wantao Wang, Donghua Hou and Wenbo Wang

Doxorubicin inhibits osteosarcoma progression by regulating circ_0000006/miR-646/ BDNF axis

Osteosarcoma (OS) is the most common aggressive bone tumor in children and teenagers. Doxorubicin (DOX) is a chemotherapeutic drug for OS. This study aims to reveal the effects and underneath mechanism of DOX ...

Authors: Abulimiti Amuti, Dehu Liu, Ayiguli Maimaiti, Yao Yu, Yalikun Yasen, Haoguang Ma, Rui Li, Shurong Deng, Fei Pang and Youliang Tian

Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review

Osteoporotic vertebral compression fracture (OVCF) is one of the most common fragile fractures, and percutaneous vertebroplasty provides considerable long-term benefits. At the same time, there are many report...

Authors: Wei Mao, Fei Dong, Guowei Huang, Peiliang He, Huan Chen, Shengnan Qin and Aiguo Li