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  1. Content type: Research article

    Alternative grafts are needed to improve the healing of bone non-union. Here, we assessed a bovine bone product which retains the inorganic and organic components of bone, as an alternative bone graft.

    Authors: David S. Musson, Ryan Gao, Maureen Watson, Jian-Ming Lin, Young-Eun Park, Donna Tuari, Karen E. Callon, Mark Zhu, Nicola Dalbeth, Dorit Naot, Jacob T. Munro and Jillian Cornish

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:60

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  2. Content type: Research article

    Proinflammatory cytokines, which can upregulate the expression of matrix-degrading enzymes in chondrocytes, play important roles in the development of osteoarthritis. BET family proteins, acting as the “reader...

    Authors: Jin Dai, Sheng Zhou, Qiting Ge, Jinzhong Qin, Jianxin Li, Huangxian Ju, Yi Cao, Minghao Zheng, Chaojun Li, Xiang Gao, Huajian Teng and Qing Jiang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:59

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  3. Content type: Research article

    Singular traumatic insults, such as bone fracture, typically initiate an appropriate immune response necessary to restore the host to pre-insult homeostasis with limited damage to self. However, multiple concu...

    Authors: Lauren H. Mangum, Joshua J. Avila, Brady J. Hurtgen, Alicia L. Lofgren and Joseph C. Wenke

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:58

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  4. Content type: Systematic review

    Ceramic bearings have been widely used in total hip arthroplasty (THA), which resulted in satisfactory clinical outcomes due to the excellent tribological characteristics of the implants. However, ceramic comp...

    Authors: Shuai Xiang, Yan Zhao, Zeng Li, Bin Feng and Xisheng Weng

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:57

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  5. Content type: Systematic review

    Recently, many studies have shown the role of hypoxia-inducible factor-1α (HIF-1α) expression in the outcome of bone tumor. However, the results remain inconclusive. It is necessary to carry out a meta-analysi...

    Authors: Deqing Luo, Hongyue Ren, Wenjiao Zhang, Hang Xian, Kejian Lian and Hui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:56

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  6. Content type: Research article

    Type 2 diabetes mellitus (T2DM) and hyperlipidemia are negatively related to bone regeneration. The aim of this study was to evaluate the effect of high-fat and high-glucose microenvironment on bone regenerati...

    Authors: Xuan Wu, Yunpeng Zhang, Yixiao Xing, Bin Zhao, Cong Zhou, Yong Wen and Xin Xu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:55

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  7. Content type: Research article

    This pilot study aimed to ascertain whether the local application of ascorbic acid (AA), of T3, and of rat (r) bone marrow mesenchymal stem cells (BMSCs), alone or in all possible combinations, promoted healing a...

    Authors: Francesco Oliva, Nicola Maffulli, Clarissa Gissi, Francesca Veronesi, Lucia Calciano, Milena Fini, Silvia Brogini, Marialucia Gallorini, Cristina Antonetti Lamorgese Passeri, Roberta Bernardini, Rosella Cicconi, Maurizio Mattei and Anna Concetta Berardi

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:54

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  8. Content type: Research article

    Reverse total shoulder arthroplasty (RTSA) is a treatment option for patients with severe osteoarthritis, rotator cuff arthropathy, or massive rotator cuff tear with pseudoparalysis. We are to deduce not only ...

    Authors: Sungwook Choi, Jong-Hwan Bae, Yong Suk Kwon and Hyunseong Kang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:53

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  9. Content type: Research article

    Tibial shaft fractures account for approximately 15% of long bone fractures. Locked plates with minimally invasive plate osteosynthesis techniques are used widely by surgeons. The purpose of this study is to i...

    Authors: Yasen Cao, Yong Zhang, Lixin Huang and Xiaowei Huang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:52

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  10. Content type: Technical note

    Unstable sacral fractures are high-energy injuries and comprise polytrauma. Internal fixation to enable withstanding vertical loads is required to get up early from the bed after an unstable sacral fracture. W...

    Authors: Akinori Okuda, Naoki Maegawa, Hiroaki Matsumori, Tomohiko Kura, Yasushi Mizutani, Hideki Shigematsu, Eiichiro Iwata, Masato Tanaka, Keisuke Masuda, Yusuke Yamamoto, Yusuke Tada, Yohei Kogeichi, Keisuke Takano, Hideki Asai, Yasuyuki Kawai, Yasuyuki Urisono…

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:51

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  11. Content type: Research article

    The aim of this study was to define deep tissue temperature during cryotherapy in postoperative hip fracture patients, by using measured skin temperature as input parameter for a simple numerical model. Second...

    Authors: Nick C. Leegwater, Sander M. van der Meer, Inger N. Sierevelt, Hugo Spruijt and Peter A. Nolte

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:49

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  12. Content type: Systematic review

    Labral repair and biceps tenotomy and tenodesis are routine operations for type II superior labrum anterior posterior (SLAP) lesion of the shoulder, but evidence of their superiority is lacking. We conducted t...

    Authors: Yi-Ming Ren, Yuan-Hui Duan, Yun-Bo Sun, Tao Yang, Wei-Yu Hou and Meng-Qiang Tian

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:48

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  13. Content type: Research article

    We described the use of the technique of L-shaped corticotomy with bone flap sliding to treat chronic osteomyelitis of the tibia in eight patients and presented the preliminary results.

    Authors: Teng-fei Lou, Gen Wen, Chun-yang Wang, Yi-min Chai, Pei Han and Xiao-fan Yin

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:47

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  14. Content type: Research article

    Lumbar spinal stenosis, often accompanied by degenerative spondylolisthesis, is one of the most common conditions in the elderly. Decompression and fusion is a well-accepted treatment for single-segment lumbar...

    Authors: Wei Sun, Cheng Xue, Xian-ye Tang, Hu Feng, Feng Yuan, Kai-jin Guo and Jie Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:46

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  15. Content type: Research article

    Considering the epidemiology of acromioclavicular (AC) dislocation related to young and active patients, the impact on working capacity is highly relevant. The purpose of this study was to determine the capaci...

    Authors: Felix Porschke, Marc Schnetzke, Stefan Studier-Fischer, Paul Alfred Gruetzner and Thorsten Guehring

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:45

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  16. Content type: Research article

    Patients undergoing total or partial arthroscopic meniscectomy for treating traumatic meniscal tears are at greater risk of developing knee osteoarthritis (OA) due to increased mechanical load. The purpose of ...

    Authors: Duraisamy Shriram, Go Yamako, Etsuo Chosa, Yee Han Dave Lee and Karupppasamy Subburaj

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:44

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  17. Content type: Research article

    Polymethylmethacrylate (PMMA) is used for local antimicrobial delivery in orthopedic infection. Oritavancin is a long half-life lipoglycopeptide with broad activity against Gram-positive bacteria. Herein, we a...

    Authors: Suzannah M. Schmidt-Malan, Kerryl E. Greenwood-Quaintance, Lawrence J. Berglund, Jayawant Mandrekar and Robin Patel

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:43

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  18. Content type: Research article

    Multiple myeloma (MM) is a blood system malignant tumor, which often leads to osteolytic bone destruction, and the vertebral column is the primary site of involvement. However, the efficacy and prognosis of pe...

    Authors: Xingchen Yao, Ziyu Xu and Xinru Du

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:42

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  19. Content type: Technical note

    While locking plates have markedly improved fixation of proximal humerus fractures, a cohort of fractures remains difficult to treat. This cohort has been identified as fractures with marked medial comminution...

    Authors: John Tristan Cassidy, Eamonn Coveney and Diarmoud Molony

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:41

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  20. Content type: Research article

    Platelet-rich plasma (PRP) is autologous in origin and contains a high concentration of platelets which is a source of various growth factors. Previous studies have suggested that PRP has a positive effect in ...

    Authors: Jen-Chung Liao

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:39

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  21. Content type: Research article

    Total hip arthroplasty for adult patients with a history of infection of the hip in childhood could be a more technically demanding procedure due to complicated anatomy and the possibility of reinfection. Here...

    Authors: Yue Luo, Zhouyuan Yang, Releken Yeersheng, Donghai Li and Pengde Kang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:38

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  22. Content type: Research article

    Clavicle fractures are common clinical problems, accounting for approximately 10% of all fractures. Neer’s type II fractures disrupt the integrity of the coracoclavicular ligament and, therefore, are inherentl...

    Authors: Yang Ruen Zheng, Yung Chang Lu and Chung Ting Liu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:37

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  23. Content type: Systematic review

    To conduct a meta-analysis to compare the curative effect of treating the full thickness tear of the rotator cuff using the arthroscopic bone marrow stimulation (BMS) technology and provide the evidence for it...

    Authors: Zhuoyang Li and Yijun Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:36

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  24. Content type: Research article

    To maintain the corrected alignment after high tibial osteotomy (HTO), fixation with titanium locking plate and screws is widely used in current practice; however, screw breakage is a common complication. Thus...

    Authors: Yen-Nien Chen, Chih-Wei Chang, Chun-Ting Li, Chih-Hsien Chen, Chi-Rung Chung, Chih-Han Chang and Yao-Te Peng

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:35

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  25. Content type: Study protocol

    Osteoarthritis is a progressive multifactorial condition of the musculoskeletal system with major symptoms including pain, loss of function, damage of articular cartilage and other tissues in the affected area...

    Authors: Meredith Harrison-Brown, Corey Scholes, Kholoud Hafsi, Maimuna Marenah, Jinjie Li, Fadi Hassan, Nicola Maffulli and William D. Murrell

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:34

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  26. Content type: Systematic review

    Fascia iliaca compartment block (FICB) provides an analgesic option for total hip arthroplasty (THA) patients. The evidence supporting FICB is still not well established. The purpose of this meta-analysis was ...

    Authors: Xiao-yan Zhang and Jian-bao Ma

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:33

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  27. Content type: Study protocol

    Both manual therapy techniques and dry needling have shown to be effective treatment options for the treatment of plantar heel pain; however, in recent years, other techniques based on dry needling (DN), such ...

    Authors: Zaid Al-Boloushi, Eva María Gómez-Trullén, Pablo Bellosta-López, María Pilar López-Royo, Daniel Fernández and Pablo Herrero

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:31

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  28. Content type: Systematic review

    Distal metadiaphyseal tibial fractures are commonly seen lower limb fractures. Intramedullary nail fixation (IMN) and plate internal fixation (PL) are the two mainstay treatments for tibial fractures, but agre...

    Authors: Liangcong Hu, Yuan Xiong, Bobin Mi, Adriana C. Panayi, Wu Zhou, Yi Liu, Jing Liu, Hang Xue, Chengcheng Yan, Abudula Abududilibaier, Lang Chen and Guohui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:30

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  29. Content type: Technical note

    Sacral fracture and sacral nerve injury remain problems in orthopedics, especially in a sacral fracture combined with an anterior sacral nerve injury. Treating a sacral nerve injury with open reduction neuroly...

    Authors: Ye Peng, Wei Zhang, Gongzi Zhang, Xiang Wang, Shuwei Zhang, Xin Ma, Peifu Tang and Lihai Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:29

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  30. Content type: Research article

    SERI (Simple, Effective, Rapid, and Inexpensive) osteotomy is an accepted minimally invasive distal first metatarsal osteotomy performed to correct hallux valgus (HV). In the absence of reports of efficacy of the...

    Authors: Talal Almalki, Raheef Alatassi, Ahmad Alajlan, Khalid Alghamdi and Abdullah Abdulaal

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:28

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  31. Content type: Research article

    Restoration of hand function after total brachial plexus root avulsion (tBPRA) is a difficult problem in surgical management. A new modified approach in repairing tBPRA is to use a subcutaneous tunnel across t...

    Authors: Juntao Feng, Tao Wang and Pengbo Luo

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:27

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  32. Content type: Systematic review

    This review compares the outcomes and complication rates of three surgical strategies used for the management of symptomatic os acromiale. The purpose of this study was to help guide best practice recommendati...

    Authors: Jennifer A. Purnell, Jonathan Bourget-Murray, Adam Kwapisz, Aaron J. Bois and Justin LeBlanc

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:26

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  33. Content type: Research article

    Due to atypical clinical presentation, wide use of antibiotics, and lack of specificity in diagnosis, diagnosis of tubercular (TB) infection in joints is increasingly difficult, and misdiagnosis is common. The...

    Authors: Xiaojun Duan and Liu Yang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:25

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  34. Content type: Research article

    There was a controversy about surgery approach of thoracic and lumbar tuberculosis (TB) treatment. The aim of this study was to compare the microbiology outcomes of the drainage liquid and the clinical outcome...

    Authors: Chen Zhao, Xiaobing Pu, Qiang Zhou, Xingzhou Huang, Chengmin Zhang, Lei Luo, Zehua Zhang, Tianyong Hou, Fei Luo, Fei Dai and Jianzhong Xu

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:24

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  35. Content type: Research article

    In lumbar spinal stenosis (LSS), at most times, several levels are impaired and selecting the correct level remains a common problem for surgeons, as surgery remains invasive, and extended laminectomy may lead...

    Authors: Hua-Biao Chen, Min Chen, Hong-Hui Peng, Qi-Feng Xu, Xin-Chun Li and Bo Bai

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:23

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  36. Content type: Research article

    Using a larger, more comprehensive sample, and inclusion of the reverse shoulder arthroplasty as a primary surgical approach for proximal humerus fracture, we report on geographic variation in the treatment of...

    Authors: Sarah B. Floyd, Joel Campbell, Cole G. Chapman, Charles A. Thigpen, Michael J. Kissenberth and John M. Brooks

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:22

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  37. Content type: Research article

    Evaluation of knee and lower limb function alone is not sufficient to assess gait. For accurate assessment of gait abnormality, gait oscillation should also be measured. The goal of this analysis was to assess...

    Authors: Takatomo Mine, Masaya Kajino, Jun Sato, Seiichi Itou, Koichiro Ihara, Hiroyuki Kawamura, Ryutaro Kuriyama and Yasuhiro Tominaga

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:21

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  38. Content type: Research article

    Screw fixation is a typical technique for the isolated subtalar joint. However, no consensus has been reached on how to select the most suitable insertion position and direction. This study aims to find the id...

    Authors: Cheng-song Yuan, Jing-jing Sun, Si-ya Wu, Guo-qing Jing, Mei-ming Xie and Kang-lai Tang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:20

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  39. Content type: Research article

    It is challenging to create an ideal artificial acetabulum during total hip arthroplasty (THA) in adult DDH. Our team developed a new patient-specific instrument (PSI) that uses the superolateral rim of the ac...

    Authors: Chenggong Wang, Han Xiao, Weiwei Yang, Long Wang, Yihe Hu, Hua Liu and Da Zhong

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:19

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  40. Content type: Review

    Tendons are soft tissues of the musculoskeletal system that are designed to facilitate joint movement. Tendons exhibit a wide range of mechanical properties matched to their functions and, as a result, have be...

    Authors: Alex Hayes, Katrina Easton, Pavan Teja Devanaboyina, Jian-Ping Wu, Thomas Brett Kirk and David Lloyd

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:18

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  41. Content type: Research article

    Kashin-Beck disease (KBD) is an endemic and chronic osteoarthropathy. At present, the diagnosis of KBD mainly depends on the X-ray examination and which could not reflect early damage of cartilage sensitively....

    Authors: Wanying Wang, Lihua Wang, Qing Deng, Yun Cai, Xianhao Wu and Liyan Sun

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:17

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  42. Content type: Research article

    Progressive pseudorheumatoid dysplasia (PPD) is a rare autosomal recessive skeletal dysplasia caused by mutations in the Wnt1-inducible signaling pathway protein 3 (WISP3) gene. Available literatures in PPD empha...

    Authors: Yan Li, Yan Zeng, Zhongqiang Chen, Haisong Xin and Xiaoliang Li

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:16

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  43. Content type: Systematic review

    Cardiac complication represents a major cause of morbidity and mortality after total joint arthroplasty, thus necessitating investigation into the associated risks in total hip arthroplasty and total knee arth...

    Authors: Yassin Elsiwy, Ivana Jovanovic, Kenji Doma, Kaushik Hazratwala and Hayley Letson

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:15

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  44. Content type: Research article

    The position of Kirschner wires (K-wires) has an influence on the outcome of modified tension-band wiring (MTBW) in fixing patella fractures. However, the instruction for K-wires positioning is not clear enoug...

    Authors: Ming Ling, Shi Zhan, Dajun Jiang, Hai Hu and Changqing Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:14

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  45. Content type: Research article

    To introduce a new method of pelvic incidence (PI) measurement based on three-dimensional (3D) pelvic models reconstructed from CT images and to report the normal distribution of PI in normal pelvic anatomy.

    Authors: Hong-Fang Chen, Jie Mi, Heng-Hui Zhang and Chang-Qing Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:13

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  46. Content type: Research article

    Bioabsorbable suture anchors have been associated with bone-derived complications, such as osteolysis and cyst formation, after rotator cuff repair. The purpose of this study was to assess the osseous degradat...

    Authors: Jan Vonhoegen, Dominik John and Constanze Hägermann

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:12

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  47. Content type: Research article

    Staphylococcus aureus (S. aureus) infection accounts for more than 50% of the osteomyelitis cases. Currently, methicillin-resistant S. aureus (MRSA) strains present an urgent medical problem. The YycFG two-compon...

    Authors: Shizhou Wu, Fuguo Huang, Hui Zhang and Lei Lei

    Citation: Journal of Orthopaedic Surgery and Research 2019 14:10

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