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  1. Unfractionated heparin (UFH) and low molecular weight heparin (LMWH) are commonly used for preventing venous thrombosis of the lower extremity in patients with traumatic spinal cord injury. Although, LMWH is t...

    Authors: Ze Lin, Yun Sun, Hang Xue, Lang Chen, Chenchen Yan, Adriana C. Panayi, Bobin Mi and Guohui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:262

    Content type: Systematic review

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  2. Many non-union animal models have been developed to explore the problems surrounding fracture healing. However, the existing models are not perfect and cannot satisfy all non-union studies. This study aimed to...

    Authors: Xue-Qiang Wu, Dong Wang, Yang Liu and Jun-Lin Zhou

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:261

    Content type: Research article

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  3. This study was aimed to utilize a modified anterior drawer test (MADT) to detect the anterior cruciate ligament (ACL) ruptures and investigate its accuracy compares with three traditional tests.

    Authors: Guang-lei Zhao, Jin-yang Lyu, Chang-quan Liu, Jian-guo Wu, Jun Xia and Gang-yong Huang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:260

    Content type: Research article

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  4. Osteoarthritis (OA) is a worldwide musculoskeletal disorder. However, disease-modifying therapies for OA are not available. Here, we aimed to characterize the molecular signatures of OA and to identify novel t...

    Authors: Song Shi, Fuyin Wan, Zhenyu Zhou, Ran Tao, Yue Lu, Ming Zhou, Fan Liu and Yake Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:259

    Content type: Research article

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  5. The management of complex diabetic foot wounds with large skin defects poses a challenge for surgeons. We presented a simple skin stretching system and negative pressure wound therapy for the repair of complex...

    Authors: Yaojun Wu, Liang Chen, Shaokun Wu, Liying Yu, Mimi Chen, Jingnan Wang, Jiejie Chen and Qingjiang Pang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:258

    Content type: Study protocol

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  6. Acromial fractures are rare and there is no consensus on fixation, but an increasing number of studies have reported using two screws to fix Ogawa type I acromial fractures. The objective of this study was to ...

    Authors: Wei Zhang, Zhongye Sun, Weiyan Li, Jun Yan, Liren Han, Shizhang Han, Xiaofei Yang and Bei Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:257

    Content type: Research article

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  7. Accurate femoral neck anteversion angle (FNA) measurement is of great significance in the diagnosis and treatment of developmental dysplasia of the hip (DDH) in children. The FNA measurement still remains a co...

    Authors: Zhencun Cai, Chengzhe Piao, Tianyu Zhang, Lianyong Li and Liangbi Xiang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:256

    Content type: Research article

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  8. Significant bone defects are associated with poor clinical results after surgical stabilization in cases of glenohumeral instability. Although multiple factors are thought to adversely affect enlargement of bi...

    Authors: Noboru Matsumura, Kazuya Kaneda, Satoshi Oki, Hiroo Kimura, Taku Suzuki, Takuji Iwamoto, Morio Matsumoto, Masaya Nakamura and Takeo Nagura

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:255

    Content type: Research article

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  9. This study aimed to investigate whether rodent shoulder specimens fixed in formaldehyde for histological and histomorphometric investigations and specimens stained using Lugol’s solution for soft tissue visual...

    Authors: Xaver Feichtinger, Patrick Heimel, Claudia Keibl, David Hercher, Jakob Emanuel Schanda, Roland Kocijan, Heinz Redl, Johannes Grillari, Christian Fialka and Rainer Mittermayr

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:254

    Content type: Research article

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  10. Circular RNA (circRNA) has been shown to be associated with osteoarthritis (OA) progression. Circ_0116061 has been found to be highly expressed in OA cartilage tissues, but its role and mechanism in OA progres...

    Authors: Wei Zheng, Guanhua Hou and Yong Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:253

    Content type: Research article

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  11. Lumbar disc degeneration (LDD) is an essential pathological mechanism related to low back pain. Current research on spinal surgery focused on the sophisticated mechanisms involved in LDD, and autophagy was reg...

    Authors: Wei-long Xu and Yan Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:252

    Content type: Research article

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  12. The aim of this retrospective study is to review our experience in the diagnosis and role of transforaminal percutaneous endoscopic discectomy (TPED) for symptomatic gas-filled discal cysts.

    Authors: Kejun Zhu and Dengwei He

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:251

    Content type: Research article

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  13. An observational study was conducted to evaluate the recovery of older children with relapsed congenital clubfoot who underwent an Achilles tenotomy for the second time as part of the Ponseti treatment.

    Authors: Manye Yao, Chunxu Zhang, Weyland Cheng, Junhong Guo and Shijie Dong

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:250

    Content type: Research article

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  14. The experiment was undertaken to estimate the effect of BMSC seeding in different scaffold incorporation with HBO on the repair of a seawater-immersed bone defect. And future compared n-HA/PLGA with β-TCP/PLGA...

    Authors: Gan Zhang, Xiaosong Chen, Xunsheng Cheng, Wuxiu Ma and Congcong Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:249

    Content type: Research article

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  15. Rich vascularity of the induced membrane (IM) is important for Masquelet reconstruction surgery. The factors affecting IM vascularity are not completely understood. This study aimed to investigate these factor...

    Authors: Takahiro Niikura, Naoe Jimbo, Masato Komatsu, Keisuke Oe, Tomoaki Fukui, Tomoyuki Matsumoto, Shinya Hayashi, Takehiko Matsushita, Yoshitada Sakai, Tomoo Itoh and Ryosuke Kuroda

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:248

    Content type: Research article

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  16. Radiographic changes that appear relatively quickly after fixation of cementless stem in total hip arthroplasty (THA) vary depending on the stem design and fixation style. The present study compared radiograph...

    Authors: Yutaro Munakata, Yujiro Kuramitsu, Yutaka Usui and Ken Okazaki

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:247

    Content type: Research article

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  17. Elderly patients who experience hip fractures often become bedridden and are at risk of developing lower respiratory tract infections. The current study was to investigate the etiology and bacterial drug resis...

    Authors: Yuan Yuan, Wei Tian, Xiaohui Deng, Rui Yue, Xiaozhu Ge, Xinbao Wu and Ping Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:246

    Content type: Research article

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  18. The hand is the second most fractured region in children. It is therefore important to update fracture epidemiology to be able to identify time trends for adequate health care planning. This study reports pedi...

    Authors: Erika Bergman, Vasileios Lempesis, Lars Jehpsson, Björn E. Rosengren and Magnus K. Karlsson

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:245

    Content type: Research article

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  19. Osteonecrosis of the femoral head (ONFH) is a debilitating condition. Vascularized iliac bone graft (VIBG) is a joint-preserving surgery to improve blood supply to the avascular portion of the femoral head whi...

    Authors: Wai-Wang Chau, Jonathan Patrick Ng, Hiu-Woo Lau, Michael Tim-Yun Ong, Kwong-Yin Chung and Kevin Ki-Wai Ho

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:244

    Content type: Research article

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  20. This study presents patient-reported outcome measures after combined matrix-associated autologous chondrocyte implantation and autologous bone grafting in high-stage osteochondral lesions of the talus in adole...

    Authors: Daniel Körner, Christoph E. Gonser, Stefan Döbele, Christian Konrads, Fabian Springer and Gabriel Keller

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:243

    Content type: Research article

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  21. We compared the measured resection (MR) technique and the gap balancing (GB) technique in patients with knee osteoarthritis after primary total knee arthroplasty (TKA) in China to understand the effects of the...

    Authors: Qingfang Xiao, Bo Liu and Binghao Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:242

    Content type: Research article

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  22. The primary aim of our study was to evaluate the comparative efficacy and safety profile of curettage and mixed bone grafting without instrument or with elastic intramedullary nailing in the treatment of humer...

    Authors: Xuan Wang, Jiuhui Han, Yazhou Li, Yuchang Liu and Junzhong Luo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:241

    Content type: Research article

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  23. The medial patellofemoral ligament (MPFL) is always damaged after patellar dislocation. In selected patients, MPFL reconstruction is necessary to restore a correct patellar tracking. Despite the large number o...

    Authors: Filippo Migliorini, Francesco Oliva, Gayle D. Maffulli, Jörg Eschweiler, Matthias Knobe, Markus Tingart and Nicola Maffulli

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:239

    Content type: Systematic review

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  24. Congenital clubfoot is one of the common congenital orthopaedic deformities. Pirani and Dimeglio scoring systems are two classification systems for measuring the severity of the clubfoot. However, the relation...

    Authors: Mohammad Ali Tahririan, Mohammadreza Piri Ardakani and Sara Kheiri

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:238

    Content type: Research article

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  25. Concerns of contracting the highly contagious disease COVID-19 have led to a reluctance in seeking medical attention, which may contribute to delayed hospital arrival among traumatic patients. The study object...

    Authors: Stephanie Jarvis, Kristin Salottolo, Robert Madayag, Jennifer Pekarek, Nnamdi Nwafo, Alexander Wessel, Therese Duane, Zachary Roberts, Mark Lieser, Chad Corrigan and David Bar-Or

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:237

    Content type: Research article

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  26. Elective total knee arthroplasty (TKA) is a common surgery which has evolved rapidly. However, there are no recent large systematic reviews of serious adverse event (SAE) rate and 30-day readmission rate (30-d...

    Authors: Costas Papakostidis, Peter V. Giannoudis, J. Tracy Watson, Robert Zura and R. Grant Steen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:236

    Content type: Systematic review

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  27. In several previous studies, Charlson comorbidity index (CCI) score was associated with postoperative complications, mortality, and re-admission. There are few reports about the influence of CCI score on posto...

    Authors: Kensuke Shinonara, Ryo Ugawa, Shinya Arataki, Shinnosuke Nakahara and Kazuhiro Takeuchi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:235

    Content type: Research article

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  28. Despite being a commonly encountered injury in orthopedic practice, controversy surrounds the methods of optimal internal fixation for femoral neck fractures (FNF) in young patients. The objective of the prese...

    Authors: Hui Sun, Lin-Yuan Shu, Matthew C. Sherrier, Yi Zhu, Jing-Wen Liu and Wei Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:234

    Content type: Research article

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  29. Insertional Achilles tendinopathy is difficult to manage, and there is no definite consensus on which nonoperative treatment is superior over the others. We aim to provide a clear summary of the best available...

    Authors: Xiaosong Zhi, Xinyuan Liu, Jing Han, Yang Xiang, Helin Wu, Shijun Wei and Feng Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:233

    Content type: Systematic review

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  30. The ipsilateral olecranon with associated radial neck fractures does not include in the Bado classification of Monteggia fractures and equivalent lesions. The primary aims of this retrospective multicenter stu...

    Authors: Jin Li, Sheng Ping Tang, Guo Xin Nan, Ming Li, Shun You Chen, Hai Bo Mei, Jing Fan Shao, Fei Jiang, Rushyuan J. Lee and Xin Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:232

    Content type: Research article

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  31. Osteosarcoma is most common malignant bone tumors. OS patients with metastasis have a poor prognosis. There are few tools to assess metastasis; we want to establish a nomogram to evaluate metastasis of osteosa...

    Authors: Shouliang Lu, Yanhua Wang, Guangfei Liu, Lu Wang, Pengfei Wu, Yong Li and Cai Cheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:231

    Content type: Research article

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  32. There are different surgical methods for primary malignant tumor located at distal tibia. Previous studies have reported that double-strut fibula ankle arthrodesis is an alternative option. The purpose of this...

    Authors: Zhiqing Zhao, Taiqiang Yan, Wei Guo, Rongli Yang and Xiaodong Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:230

    Content type: Research article

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  33. The aim of this meta-analysis was to systematically evaluate the clinical efficacy and safety of short-course chemotherapy (≤ 6 months) compared with the standard therapy (9–18 months) for patients with spinal...

    Authors: Lu Lin, Zhenyong Ke and Si Cheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:229

    Content type: Systematic review

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  34. To test the validity of a second-generation appropriateness system in a cohort of patients undergoing total knee arthroplasty (TKA).

    Authors: Antonio Escobar, Amaia Bilbao, Maria L. Bertrand, Jesús Moreta, Miquel A. Froufe, Jordi Colomina, Olga Martınez-Cruz, Robert A. Perera and Daniel L. Riddle

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:227

    Content type: Research article

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  35. Osteosarcoma is the most common primary bone cancer occurring in young adults and the 5-year survival rate of patients with metastatic osteosarcoma is less than 30% due to high metastatic recurrence and drug r...

    Authors: Jianping Zhang, Na Li, Siyu Lu, Yanling Chen, Lequn Shan, Xingcheng Zhao and Yongqing Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:226

    Content type: Research article

    Published on:

  36. How to perform minimally-invasive surgery on Tile C pelvic fractures is very difficult, and it is also a hot topic in orthopedic trauma research. We applied minimally-invasive treatment using an anterior inter...

    Authors: Lin Liu, Donggui Zeng, Shicai Fan, Yongxing Peng, Hui Song, Dadi Jin and Letian Zeng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:225

    Content type: Research article

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  37. The treatment for displaced Salter-Harris II (S-H II) distal tibia fractures remains controversial. The purpose of this study was to review S-H II distal tibia fractures and evaluate the rate of premature phys...

    Authors: Quanwen Yuan, Yunfang Zhen, Zhixiong Guo, Fuyong Zhang, Jianfeng Fang, Zhenhua Zhu, Lunqing Zhu, Xiaofang Shen, Chunhua Yin, Yao Liu, Feng Yao, Lin Wu and Xiaodong Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:224

    Content type: Research article

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  38. Alcohol-induced osteonecrosis of the femoral head (ONFH) is a complex and heterogeneous disease. Genetic factors and epigenetic modifications are one of the pathogenesis of the disease. However, the influence ...

    Authors: Tiantian Wang, Fei Wang, Tingting Liu, Menghu Sun, Feimeng An, Chang Liu, Ye Tian, Yuju Cao and Jianzhong Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:223

    Content type: Research article

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  39. Quite a few traumatic spinal cord injuries (TSCI) were caused by falls. However, the comparison of different causes of TSCI or the epidemiological characteristics of TSCI caused by falls of different heights a...

    Authors: Zhen-Rong Zhang, Yao Wu, Fang-Yong Wang and Wen-Jing Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:222

    Content type: Research article

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  40. Broken stems are particularly challenging in revision hip arthroplasty, as no standard extraction instruments fit anymore. Well-integrated uncemented stem remnants can be particularly arduous to remove. Stem f...

    Authors: Peter Wahl, Theo Solinger, Michel Schläppi and Emanuel Gautier

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:221

    Content type: Technical note

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  41. Iliac crest is the most preferred autogenous bone graft harvesting donor site while it has sorts of complications like prolonged pain, hematoma, and fracture. Harvesting cancellous bone from proximal tibia is ...

    Authors: Hanju Kim, Ajit Kumar Kar, Aditya Kaja, Eic Ju Lim, Wonseok Choi, Whee Sung Son, Jong-Keon Oh, Seungyeob Sakong and Jae-Woo Cho

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:220

    Content type: Research article

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  42. Pedicle screw loosening is a major complication following spinal fixation associated with osteoporosis in elderly. However, denosumab is a promising treatment in patients with osteoporosis. The effect of denos...

    Authors: Soji Tani, Koji Ishikawa, Yoshifumi Kudo, Koki Tsuchiya, Akira Matsuoka, Hiroshi Maruyama, Haruka Emori, Ryo Yamamura, Chikara Hayakawa, Masaya Sekimizu, Yusuke Oshita, Tomoyuki Ozawa, Toshiyuki Shirahata, Takashi Nagai, Tomoaki Toyone and Katsunori Inagaki

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:219

    Content type: Research article

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  43. Some propitious mid- and long-term studies had been reported for MoM bearings; however, most studies have addressed specific patient groups rather than younger, active patients, who probably represent the most...

    Authors: Sheng-Yu Jin, Jing-Yao Jin, Joon-Kyoo Kang, Taek-Rim Yoon and Kyung-Soon Park

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:218

    Content type: Research article

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  44. Although excellent clinical outcomes of supercapsular percutaneously assisted total hip arthroplasty (SuperPath) have been reported, the peri-operative blood loss has rarely been reported. The current study de...

    Authors: Yong Hu, Min-Cong Wang, Tao Wang, Yue Meng, Xiao-Min Chao, Hui-Feng Zhu, Cheng-Guo Li, Cheng-Long Pan and He-Bei He

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:217

    Content type: Research article

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  45. The prevalence of osteoporosis is rising steadily as the aging population increases. Bone mineral density (BMD) assessment is a golden standard to establish the diagnosis of osteoporosis. However, the accessib...

    Authors: Wei-Hsiu Hsu, Wei-Bin Hsu, Chun-Hao Fan and Robert Wen-Wei Hsu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:215

    Content type: Research article

    Published on:

  46. This study compared the biomechanics of artificial pedicle fixation in spine reconstruction with a 3-dimensional (3D)-printed prosthesis after total en bloc spondylectomy (TES) by finite element analysis.

    Authors: Xiaodong Wang, Hanpeng Xu, Ye Han, Jincheng Wu, Yang Song, Yuanyuan Jiang, Jianzhong Wang and Jun Miao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:213

    Content type: Research article

    Published on:

  47. To manage patellofemoral joint disorders, a complete understanding of the in vivo patellofemoral kinematics is critical. However, as one of the parameters of joint kinematics, the location and orientation of t...

    Authors: Zhenguo Yu, Hong Cai, Bin Yang, Jie Yao, Ke Zhang, Hua Tian and Zhongjun Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:212

    Content type: Research article

    Published on:

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