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  1. This study hoped to explore the potential biomarkers and associated metabolites during osteosarcoma (OS) progression based on bioinformatics integrated analysis.

    Authors: Jun Wang, Mingzhi Gong, Zhenggang Xiong, Yangyang Zhao and Deguo Xing
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:432
  2. When approaching a joint replacement procedure, pre-surgical planning is essential to predict an accurate estimation of implant size and position. There are currently two methods to achieve it, analog and digi...

    Authors: Luis Fernando Useche Gómez, Hernando Gaitán-Lee, María Alejandra Duarte, Patrick Dennis Halley, Alejandro Romero Jaramillo and Efraim Leal García
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:431
  3. Diastasis of the pubic symphysis has been reported to occur in 13–16% of pelvic ring injuries. In Asians, there are only a few data showing the width of the pubic symphysis. The aim of this study is to see the...

    Authors: Kun Hwang, Xiajing Wu and Chan Yong Park
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:430
  4. To compare the biomechanical stability of transsacral-transiliac screw fixation and lumbopelvic fixation for “H”- and “U”-type sacrum fractures with traumatic spondylopelvic dissociation.

    Authors: Ye Peng, Gongzi Zhang, Shuwei Zhang, Xinran Ji, Junwei Li, Chengfei Du, Wen Zhao and Lihai Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:428
  5. Corrective osteotomies for complex proximal femoral deformities can be challenging; wherefore, subsidies in preoperative planning and during surgical procedures are considered helpful. Three-dimensional (3D) p...

    Authors: Lukas Jud, Lazaros Vlachopoulos and Karl Grob
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:427
  6. Percutaneous release of the A1 pulley has been introduced as a therapeutic approach for trigger fingers and is suggested as an effective and safe alternative, where conservative treatments fail. The aim of the...

    Authors: Abbas Abdoli, Majid Asadian, Seyed Houssein Saeed Banadaky and Rabeah Sarram
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:426
  7. The Opti_Knee system, a marker-based motion capture system, tracks and analyzes the 6 degrees of freedom (6DOF) motion of the knee joint. However, the validation of the accuracy of this gait system had not bee...

    Authors: Shaobai Wang, Xiaolong Zeng, Liang Huangfu, Zhenyan Xie, Limin Ma, Wenhan Huang and Yu Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:425
  8. The purpose of total hip arthroplasty (THA) post-surgery and proper physiotherapy is positive recovery for the patient. Consideration is given to hip replacement biomechanics by ensuring no discrepancies in li...

    Authors: Maliha Fansur, Nagib A. Yurdi and Reinhard Stoewe
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:424
  9. Few studies have addressed the impact of palliative surgery for cervical spine metastasis on patients’ performance status (PS) and quality of life (QOL). We investigated the surgical outcomes of patients with ...

    Authors: Yutaro Kanda, Kenichiro Kakutani, Yoshitada Sakai, Zhongying Zhang, Takashi Yurube, Shingo Miyazaki, Yuji Kakiuchi, Yoshiki Takeoka, Ryu Tsujimoto, Kunihiko Miyazaki, Hiroki Ohnishi, Yuichi Hoshino, Toru Takada and Ryosuke Kuroda
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:423
  10. When symptomatic spondylolysis fail to respond to nonoperative treatment, surgical management may be required. A number of techniques have been described for repair by intrasegmental fixation with good results...

    Authors: Zhi-Cheng Zhang, Yang Zhang, Li-Zhi Zhang, Kai Guan, Guang-Min Zhao, Da-Jiang Ren, Fang Li and Tian-Sheng Sun
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:422
  11. Long non-coding RNAs (lncRNAs) participate in regulation of gene transcription, but little is known about the correlation among resveratrol and lncRNAs. This study aimed to identify and validate the key lncRNA...

    Authors: Hong Yi, Wei Zhang, Sheng-Yu Cui, Jian-Bo Fan, Xin-Hui Zhu and Wei Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:421
  12. The growth differentiation factor 5 (GDF5) gene regulates the growth of neuronal axons and dendrites and plays a role in the inflammatory response and tissue damage. The gene may also be associated with chroni...

    Authors: Shaoyao Yan, Huiyong Nie, Gang Bu, Weili Yuan and Suoliang Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:420
  13. Walking is a fundamental part of living, and its importance is not limited by age or medical status. Reduced walking speed (WS), or gait velocity, is a sign of advancing age, various disease states, cognitive ...

    Authors: Callum Betteridge, Ralph Jasper Mobbs and Daniel Ho
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:419
  14. The aim of this study was to compare the outcomes of cemented and uncemented hemiarthroplasty for femoral neck fractures in patients with neuromuscular disease.

    Authors: Yuchuan Wang, Zhongzheng Wang, Siyu Tian, Zhanchao Tan, Yanbin Zhu, Wei Chen and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:418
  15. In cemented primary total knee arthroplasty (TKA), aseptic loosening remains a major cause for failure. Cementing techniques and characteristics of a chosen cement play a key role for good fixation and implant...

    Authors: Hans Bösebeck, Anna-Maria Holl, Peter Ochsner, Manuel Groth, Kevin Stippich, Andrej M. Nowakowski, Christian Egloff, Sebastian Hoechel, Beat Göpfert and Sebastian Vogt
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:417
  16. The present study investigated the influence of ischemic postconditioning (I-postC) on the adjustment of renal injury after limb ischemia-reperfusion (I/R) injury, to elucidate the mechanisms of the Toll-like ...

    Authors: Zhongdi Liu, Wei Huang, Yifan Chen, Zhe Du, Fengxue Zhu, Tianbing Wang and Baoguo Jiang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:416
  17. Recent studies indicate that, in addition to antibody production, lymphocyte responses to SARS-CoV-2 may play an important role in protective immunity to COVID-19 and a percentage of the general population may...

    Authors: Marco S. Caicedo, Vianey Flores, Alicia Padilla, Samelko Lauryn, Joshua J. Jacobs and Nadim J. Hallab
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:415
  18. A defective nutrient foramen in the fovea capitis femoris was hypothesized to reflect the blood circulation pattern of the femoral head, leading to insufficient blood supply and causing osteonecrosis of the fe...

    Authors: Keyang Zhao, Fangfang Zhang, Kun Quan, Bin Zhu, Guangyi Li and Jiong Mei
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:414
  19. The network of intermediate filament proteins underlying the inner nuclear membrane forms the nuclear lamin. A- and B-type lamins are the major components of the nuclear lamina. Lamins function in many nuclear...

    Authors: Stefano Gumina, Barbara Peruzzi, Martina Leopizzi, Natale Porta, Valeria Di Maio, Carlo Della Rocca and Vittorio Candela
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:413
  20. To investigate the expression of miR-195 and its target gene Bcl-2 in intervertebral disc degeneration (IVDD) and its effect on nucleus pulposus (NP) cell apoptosis.

    Authors: Xue-Lin Lin, Zhao-Yun Zheng, Qing-Shan Zhang, Zhen Zhang and You-Zhi An
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:412
  21. Osteoarthritis (OA) is a joint disease characterized via destruction of cartilage. Chondrocyte damage is associated with cartilage destruction during OA. Long noncoding RNAs (lncRNAs) are implicated in the reg...

    Authors: Jipeng Lu, Zhongxiong Wu and Ying Xiong
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:410
  22. Percutaneous pinning fixation (PCP) has been used for the treatment of distal radius fractures for decades, especially in the elderly with fragile soft tissue. However, achieving and maintaining a sound anatom...

    Authors: Bin Zhao, Wenqian Zhao, Isaac Assan, Zhenji Li and Rongxiu Bi
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:409
  23. Tourniquets are widely used in total knee arthroplasty (TKA), but the issue of their safety remains controversial. Previous studies have focused on TKA blood loss, duration of surgery, and hemostatic drugs. Th...

    Authors: Jia Xie, Hao Yu, Fangyuan Wang, Juehua Jing and Jun Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:408
  24. In tibial plateau fractures, the posterolateral segment of the tibia plateau is frequently affected and challenging to treat. Although there are many surgical approaches and fixation methods for the treatment ...

    Authors: Yu-Feng Chen, Dong Ren, Lin-Dan Geng, Shuang-Quan Yao, Zhao-Hui Song, Liang Guang, Tian-Ci Wang and Peng-Cheng Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:407
  25. This study aimed to explore the preoperative risk factors related to blood transfusion after hip fracture operations and to establish a nomogram prediction model. The application of this model will likely redu...

    Authors: Fu Cheng Bian, Xiao Kang Cheng and Yong Sheng An
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:406
  26. The surgical treatment of displaced proximal humeral fractures is commonly affected by implant-related complications. We evaluated the functional and radiographic results of transosseous suture fixation in a s...

    Authors: J. Miquel, R. Martínez, F. Santana, P. Marimon and C. Torrens
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:405
  27. The preoperative prevalence of deep venous thromboembolism (DVT) of patella fracture is not well established. The study aimed to investigate the preoperative prevalence, the associated risk factors, and the lo...

    Authors: Zhanchao Tan, Hongzhi Hu, Zhongzheng Wang, Yuchuan Wang and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:404
  28. Authors: Sandra Iglesias-Rodríguez, Diego Matías Domínguez-Prado, Alejandro García-Reza, Daniel Fernández-Fernández, Elena Pérez-Alfonso, Javier García-Piñeiro and Manuel Castro-Menéndez
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:402
  29. Although intravenous tranexamic acid administration (ivTXA) has prevailed in clinical antifibrinolytic treatment, whether it increases thromboembolic risks has remained controversial. As a potent alternative t...

    Authors: Shangyi Hui, Yue Peng, Liyuan Tao, Shengru Wang, Yang Yang, You Du, Jianguo Zhang and Qianyu Zhuang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:401
  30. To compare the efficacy and safety between denosumab and zoledronic acid for advanced cancer with bone metastasis.

    Authors: Lianghai Jiang, Xianghua Cui, Haoning Ma and Xiangsheng Tang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:400
  31. Osteoarthritis (OA) is one kind of degenerative joint disease that happens in articular cartilage and other joint tissues. Long non-coding RNAs (lncRNAs) have been reported to serve as pivotal regulators in ma...

    Authors: Chang Zhou, Tianda He and Liji Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:399
  32. Percutaneous transforaminal endoscopic discectomy (PTED) is minimally invasive and has been widely used to treat patients with lumbar disc herniation (LDH) due to its safety and efficiency. However, due to the...

    Authors: Jinlong Liu, Junlong Wu, Honglei Zhang, Rui Zuo, Jiabin Liu and Chao Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:398
  33. Osteoporosis is a common disease closely associated with aging. In this study, we aimed to investigate the role of Cornuside I in promoting osteogenic differentiation of bone mesenchymal stem cells (BMSCs) and...

    Authors: Feng Gao, Sheng-Li Xia, Xiu-Hui Wang, Xiao-Xiao Zhou and Jun Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:397
  34. The standard surgical treatment for supracondylar humeral fractures in children is closed reduction and percutaneous pinning. Given the need for greater fixation strength and higher risk of joint stiffness for...

    Authors: Man He, Qian Wang, Jingxin Zhao, Yu Jin and Yu Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:396
  35. Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, and fibroblast-like synoviocytes (FLSs) are key effector cells in RA development. Mounting evidence indicates that circular RNAs (circRNAs) pa...

    Authors: Zhihuan Luo, Shaojian Chen and Xiaguang Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:395
  36. The aim of this study is to analyze the efficacy of open reduction and Herbert screw fixation for coronal fractures of the capitellum via the anterior approach in adolescents.

    Authors: Lingpeng Ju, Linjun Jiang, Yuan Zhang, Jun Wu, Ming Li, Xing Liu and Xiangyang Qu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:394
  37. With a reported rate of 0.7–20%, postoperative spinal implant infection (PSII) is one of the most common complications after spine surgery. While in arthroplasty both haematoma formation and perioperative bloo...

    Authors: Friederike Schömig, Justus Bürger, Zhouyang Hu, Axel Pruß, Edda Klotz, Matthias Pumberger and Christian Hipfl
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:393
  38. Osteoarthritis (OA) is responsible for the impotent disability in old people. Circular RNA (circRNA) has been reported to be related to the development of diseases. The lack of research on the role of circRNA ...

    Authors: Yongqiang Liu, Qian Li, Zhida Gao, Fang Lei and Xuefeng Gao
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:392
  39. The superior facet arthroplasty is important for intervertebral foramen microscopy. To our knowledge, there is no study about the postoperative biomechanics of adjacent L4/L5 segments after different methods o...

    Authors: Zewen Shi, Lin Shi, Xianjun Chen, Jiangtao Liu, Haihao Wu, Chenghao Wang, Zeming Chen, Fang Yang, Sheng Yu and Qingjiang Pang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:391
  40. Despite the innovations in total knee arthroplasty (TKA), there is still a subset of patients who do not acquire significant relief or expected satisfaction after primary TKA. However, this subgroup of patient...

    Authors: Xiao Yu Fan, Jin Hui Ma, Xinjie Wu, Xin Xu, Lijun Shi, Tengqi Li, Peixu Wang, Chengxin Li, Zhizhuo Li, Qing Yu Zhang and Wei Sun
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:389
  41. One of the values determined during the assessment of knee issues is the posterior tibial slope (PTS). A new option for measuring the PTS is the EOS 3D imaging system, which provides anteroposterior (AP) and l...

    Authors: Andreas Hecker, Till D. Lerch, Rainer J. Egli, Emanuel F. Liechti and Frank M. Klenke
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:388
  42. Hip fractures are common in elderly patients, in whom it is important to monitor blood loss; however, unnecessary transfusions should be avoided. The primary objective of this study was to assess whether the e...

    Authors: Marco Quaranta, Luca Miranda, Francesco Oliva, Filippo Migliorini, Gabriela Pezzuti and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:387
  43. In cases of postoperative deep wound infection after interbody fusion with cages, it is often difficult to decide whether to preserve or remove the cages, and there is no consensus on the optimal approach for ...

    Authors: Yun-Da Li, Jia-En Chi, Ping-Yeh Chiu, Fu-Cheng Kao, Po-Liang Lai and Tsung-Ting Tsai
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:386
  44. Arthroscopic rotator cuff surgery is an effective treatment for rotator cuff tears with the considered use of double-row repair techniques becoming popular in the last decade. We aim to compare the effects of ...

    Authors: Kaya Turan, Haluk Çabuk, Cenk Köroğlu and Çağatay Öztürk
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:385
  45. Lumbar degenerative spondylolisthesis (DS) has been a common disease that makes increasing patients to suffer from different degrees of low back pain and radicular symptoms. The Spinal Deformity Study Group (S...

    Authors: Zhengwang Sun, Chongqing Xu, Mengchen Yin and Wangjun Yan
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:384
  46. Increased tibial tubercle-trochlear groove distance (TT-TG) was proposed as one of the main risk factors for patellofemoral instability (PFI). The increased TT-TG distance indicated externalization of the tibi...

    Authors: Conglei Dong, Chao Zhao, Ming Li, Chongyi Fan, Xunkai Feng, Kang Piao, Kuo Hao and Fei Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:383

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