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  1. Recent studies have shown high expression levels of certain inflammatory, anabolic, and catabolic genes in the articular cartilage from the impingement zone of the hips with femoroacetabular impingement (FAI),...

    Authors: Guanying Gao, Ruiqi Wu, Rongge Liu, Jianquan Wang, Yingfang Ao and Yan Xu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:348

    Content type: Research article

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  2. The fibula is only indirectly involved in the composition of the human knee joint and has therefore been neglected in the research on knee osteoarthritis. Nonuniform settlement of the proximal tibia plateau is...

    Authors: Wen-Bin Jiang, Shi-Zhu Sun, Chan Li, Philip Adds, Wei Tang, Wei Chen, Sheng-Bo Yu and Hong-Jin Sui

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:346

    Content type: Research article

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  3. In the trauma center wards, it is not unusual for patients to have sleep disorders, especially patients with an acute injury. Meanwhile, there is substantial evidence that sleep disorder is a predictor of depr...

    Authors: Hai Yang, Yi-jia Liu, Jia-lu Ye, Li-hong Zhao, Ling-li Li and Xiao-ling Hou

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:344

    Content type: Research article

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  4. Surgical resection and reconstruction for low-grade bone sarcoma in the metaphysis of the distal femur remain challenging. We hypothesized that 3D printing osteotomy guide plate could assist to accurately rese...

    Authors: Hongwei Wu, Shuo Yang, Jianfan Liu, Linqin Li, Yi Luo, Zixun Dai, Xin Wang, Xinyu Yao, Feng Zhou and Xian’an Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:343

    Content type: Technical note

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  5. Total knee arthroplasty (TKA) is an accepted, effective treatment to restore function, relieve pain, and improve the quality of life in patients with advanced osteoarthritis. One complication of this major sur...

    Authors: Ali Alipourian, Negin Farhadian, Ehsan Zereshki and Habibollah Khazaie

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:342

    Content type: Systematic review

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  6. To investigate the clinical effect of gastrocnemius muscle flaps combined with vancomycin/gentamicin-calcium sulfate combined and autologous iliac bone graft in the phase I treatment of traumatic focal osteomy...

    Authors: Weiwei Ruan, Menglu Li, Qiaofeng Guo and Bingyuan Lin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:341

    Content type: Research article

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  7. This study aimed to retrospectively analyze clinical data of a series of patients with severe open fractures of extremities (Gustilo IIIb or IIIc), who achieved a satisfactory outcome through radical orthoplas...

    Authors: Zhao Yang, Chao Xu, Yong-Gang Zhu, Jun Li, Zi-Xiang Wu, Ji-Wei Zou, Bao-Bao Xue, Dan-Min Miao, Lei Shang and Guang-Yue Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:340

    Content type: Research article

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  8. Despite gluteus medius (GMED) tendinosis being relatively common, its presence in association with hip osteoarthritis (OA) or total hip arthroplasty (THA) is not well studied. It was hypothesized that more ten...

    Authors: Mustafa Ibrahim, Urban Hedlundh, Ninni Sernert, Khaled Meknas, Lars Haag, Tomas Movin, Nikos Papadogiannakis and Jüri-Toomas Kartus

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:339

    Content type: Research article

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  9. Several malreduction criteria have been proposed for ankle surgery, but the criteria of most importance for functional outcome remain undetermined. Furthermore, the acute inflammatory response in the ankle joi...

    Authors: That Minh Pham, Emil Bjoertomt Kristiansen, Lars Henrik Frich, Kate Lykke Lambertsen, Søren Overgaard and Hagen Schmal

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:338

    Content type: Research article

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  10. A trochlear osteotomy aims to restore patellar stability in patients with recurrent patellar instability and trochlear dysplasia. The age of patients at time of surgery could be a relevant factor which influen...

    Authors: Jordy D. P. van Sambeeck, Nico Verdonschot, Albert Van Kampen and Sebastiaan A. W. van de Groes

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:337

    Content type: Research article

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  11. We report our experiences with COVID-19 in one of the largest referral orthopedic centers in the Middle East and aimed to describe the epidemiology and clinical characteristics of these patients.

    Authors: Abolfazl Bagherifard, Peyman Arasteh, Mostafa Salehpour, Hooman Shariat Zadeh, Farid Najd Mazhar, Hasan Ghandhari, Mohammad Reza Bahaeddini, Pouria Tabrizian and Alireza Askari

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:336

    Content type: Research article

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  12. Hip geometry influences hip fracture risk. Hip fractures are common, and they are associated with pain, disability, premature death and marked costs on society. Osteoporotic fractures are frequent in Arctic po...

    Authors: Inuuteq Fleischer, Mogens Laursen and Stig Andersen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:335

    Content type: Research article

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  13. Osteoporosis is a common disease in aging populations. However, osteoporosis treatment is still challenging. Here, we aimed to investigate the role of neohesperidin (NEO) in osteoporosis progression and the po...

    Authors: Yue-wen Chang, Wen-jun Zhu, Wei Gu, Jun Sun, Zhi-qiang Li and Xiao-en Wei

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:334

    Content type: Research article

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  14. Studies evaluating the role of both corticosteroids and platelet-rich plasma (PRP) in the treatment of rotator cuff (RC) tendinopathies have been contradicting.

    Authors: Haleh Dadgostar, Farinaz Fahimipour, Alireza Pahlevan Sabagh, Peyman Arasteh and Mohammad Razi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:333

    Content type: Research article

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  15. This study aimed to predict C5 palsy (C5P) after posterior laminectomy and fusion (PLF) with cervical myelopathy (CM) from routinely available variables using a support vector machine (SVM) method.

    Authors: Haosheng Wang, Zhi-Ri Tang, Wenle Li, Tingting Fan, Jianwu Zhao, Mingyang Kang, Rongpeng Dong and Yang Qu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:332

    Content type: Research article

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  16. Authors: Virginia Veronica Visconti, Chiara Greggi, Simona Fittipaldi, Donato Casamassima, Mariagrazia Tallarico, Francesco Romano, Annalisa Botta and Umberto Tarantino

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:331

    Content type: Correction

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    The original article was published in Journal of Orthopaedic Surgery and Research 2021 16:288

  17. To investigate the effect of complete rupture of the posterior cruciate ligament (PCL) on the biomechanics and histology of the medial collateral ligament (MCL).

    Authors: Wen-qing Xie, Miao He, Yu-qiong He, Deng-jie Yu, Hong-fu Jin, Fang Yu and Yu-sheng Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:330

    Content type: Research article

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  18. Although total knee arthroplasty (TKA) is an efficacious treatment for end-stage osteoarthritis, ~20% of patients are dissatisfied with the results. We determined which factors contribute to patient satisfacti...

    Authors: Jinyu Liu, Yi Yang, Shengcheng Wan, Zhenjun Yao, Ying Zhang, Yueqi Zhang, Peng Shi and Chi Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:329

    Content type: Research article

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  19. Steroid-induced osteonecrosis of the femoral head (ONFH) is a common hip joint disease and is difficult to be diagnosed early. At present, the pathogenesis of steroid-induced ONFH remains unclear, and recogniz...

    Authors: Tianye Lin, Weijian Chen, Peng Yang, Ziqi Li, Qiushi Wei, Du Liang, Haibin Wang, Wei He and Qingwen Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:327

    Content type: Research article

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  20. Conventional percutaneous vertebroplasty (PVP) are mainly guided by C-arm fluoroscopy, and it usually leads to excessive X-ray radiation exposure to patients, surgeons, and anesthetists. Moreover, multi-time f...

    Authors: Pei Lun Hu, Ji Sheng Lin, Hai Meng, Nan Su, Yong Yang and Qi Fei

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:326

    Content type: Research article

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  21. The neuropeptide vasoactive intestinal peptide is a 28-amino acid neuropeptide that has been shown to stimulate bone repair and angiogenesis. The purpose of this study was to explore the potential role of seru...

    Authors: Ming Liu, Gan Zhao and Biao-Fang Wei

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:325

    Content type: Research article

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  22. Two minimally invasive approaches showed some advantages in outcomes compared to conventional approaches (CAs)—the direct anterior approach (DAA) and the supercapsular percutaneously assisted approach in THA (...

    Authors: Nikolai Ramadanov, Simon Bueschges, Kuiliang Liu, Philip Lazaru and Ivan Marintschev

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:324

    Content type: Systematic review

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  23. Patellofemoral pain is a common condition. The Kujala score is a well-established scoring system to assess anterior knee pain and has been translated into many languages including Arabic. The purpose of this c...

    Authors: Bassem I. Haddad, Mohammad Hamdan, Ula Isleem, Munther Ghassan Al-Saber, Fadi A. Al-Hadidi, Saif Aldeen AlRyalat and Fatima Alnaimat

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:323

    Content type: Research article

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  24. Greater trochanteric pain syndrome encompasses a range of causes of lateral hip pain including greater trochanteric bursitis, tendinopathy and tears of the gluteus minimus and medius, and lateral snapping hip ...

    Authors: Manuel Villanueva, Álvaro Iborra, Pablo Sanz-Ruiz and Concepción Noriega

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:322

    Content type: Research article

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  25. This study aimed to explore the correlation between the SRY-related high-mobility-group box gene 4 (SOX4) 3′ untranslated region (UTR) single nucleotide polymorphism (SNP) and osteoporosis susceptibility.

    Authors: Guo Li, Zuchao Gu, Yue He, Chongwen Wang and JiQiang Duan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:321

    Content type: Research article

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  26. Anemia is common among ortho-geriatric hip fracture patients and is associated with prolonged recovery and increased postoperative mortality rate. Intravenous iron seems to increase hemoglobin recovery and red...

    Authors: Silas Zacharias Clemmensen, Kristian H. Kragholm, Dorte Melgaard, Lene T. Hansen, Johannes Riis, Christian Cavallius, Marianne M. Mørch and Maria Lukács Krogager

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:320

    Content type: Research article

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  27. Periprosthetic joint infection (PJI) is a serious complication of total joint arthroplasty. We performed a retrospective cohort study to evaluate (1) the change of coagulation profile in two-staged arthroplast...

    Authors: Hao Li, Rui Li, L. L. Li, Wei Chai, Chi Xu and Jiying Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:319

    Content type: Research article

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  28. Biochemical markers of bone turnover (BTMs), such as bone alkaline phosphatase (bALP), procollagen type I N propeptide (PINP), serum cross-linked C-telopeptides of type I collagen (bCTx), and urinary cross-lin...

    Authors: Filippo Migliorini, Nicola Maffulli, Filippo Spiezia, Markus Tingart, Peretti Giuseppe Maria and Giorgino Riccardo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:318

    Content type: Systematic review

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  29. Fractures in the ankylotic spine may have an insidious presentation but are prone to displace with devastating consequences. The long lever arm of ankylosed spine fragments may lead to pulmonary and great vess...

    Authors: Rina E. Buxbaum, Adi Shani, Hani Mulla, Alon Rod and Nimrod Rahamimov

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:317

    Content type: Research article

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  30. There is great design variability on short femoral stems available on the market. This study aims to evaluate the short-term clinical and radiological results of two different design short femoral stems, both ...

    Authors: I. Tatani, K. Solou, A. Panagopoulos, J. Lakoumentas, A. Kouzelis and P. Megas

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:316

    Content type: Research article

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  31. Preoperative posterior tilt is a risk factor for fixation failure in femoral neck fractures. This study aimed to evaluate the configuration of anterior positioning screw in proximal femoral plating in the trea...

    Authors: Sheng-Bo Nie, Jun-Feng Liu, Jiang-Hua Zhu, Zi-Fei Zhou, Lei Zhang and Long-Po Zheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:315

    Content type: Research article

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  32. The extraction of a femoral stem during the revision hip arthroplasty can be a daunting task and can lead to catastrophic complications for the patient. A sound technique employed intraoperatively helps in the...

    Authors: Amit Singh, Sunirmal Mukherjee, Kuntal Patel, Deepak Herlekar, Srikant Gandavaram and Nicholas Charalambous

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:314

    Content type: Research article

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  33. Growing evidence has implicated core-binding factor beta (Cbfb) as a contributor to osteoblast differentiation, which plays a key role in fracture healing. Herein, we aimed to assess whether Cbfb affects osteo...

    Authors: Tuanmao Guo, Yanli Xing, Zhongning Chen, Xianhong Wang, Haiyun Zhu, Lan Yang and Yong Yan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:313

    Content type: Research article

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  34. The purpose of this research is to evaluate the risk factors and incidence of pulmonary cement embolism (PCE) during percutaneous vertebroplasty (PVP) or kyphoplasty (PKP) for osteoporotic vertebral compressio...

    Authors: Dexin Zou, Shengjie Dong, Wei Du, Bing Sun and Xifa Wu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:312

    Content type: Research article

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  35. A recent genome-wide association study identified a susceptible locus in MIR4300HG gene that was associated with curve progression of adolescent idiopathic scoliosis (AIS) in the Japanese population. However, ...

    Authors: Yuwen Wang, Zhicheng Dai, Zhichong Wu, Zhenhua Feng, Zhen Liu, Xu Sun, Leilei Xu, Yong Qiu and Zezhang Zhu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:311

    Content type: Research article

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  36. In fracture-related infections (FRI), both the diagnosis of the infection and the identification of the causative pathogen are crucial to optimize treatment outcomes. Sonication has been successfully used for ...

    Authors: Petri Bellova, Veronika Knop-Hammad, Matthias Königshausen, Thomas A. Schildhauer, Jan Gessmann and Hinnerk Baecker

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:310

    Content type: Research article

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  37. The purpose of this study was to determine whether the gap-balancing technique with patient-specific instrumentation (PSI) and a new balancing device in total knee arthroplasty (TKA) can improve knee function ...

    Authors: Ting Deng, Tangyou Liu, Qing Lei, Lihong Cai and Song Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:309

    Content type: Research article

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  38. Robot-assisted platforms in spine surgery have rapidly developed into an attractive technology for both the surgeon and patient. Although current literature is promising, more clinical data is needed. The purp...

    Authors: Nathan J. Lee, Ian A. Buchanan, Venkat Boddapati, Justin Mathew, Gerard Marciano, Paul J. Park, Eric Leung, Avery L. Buchholz, John Pollina, Ehsan Jazini, Colin Haines, Thomas C. Schuler, Christopher R. Good, Joseph M. Lombardi and Ronald A. Lehman

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:308

    Content type: Research article

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  39. Mounting evidence indicates that circular RNAs (circRNAs) participate in the occurrence and development of various diseases, including osteoarthritis (OA). However, the effects and molecular mechanism of circ_...

    Authors: Chao Liu, Ping Cheng, Jianjun Liang, Xiaoming Zhao and Wei Du

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:307

    Content type: Research article

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  40. The purpose of this study was to evaluate and compare the feasibility, safety, and efficacy of conventional open pedicle screw fixation (COPSF), percutaneous pedicle screw fixation (PPSF), and paraspinal poste...

    Authors: Chao Zhu, Bin Wang, Jian Yin and Xin Hui Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:306

    Content type: Research article

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  41. Soft tissue balancing is essential for the success of total knee arthroplasty (TKA) and is mainly dependent on surgeon-defined assessment (SDA) or a gap-balancer (GB). However, an electronic sensor has been de...

    Authors: Ran Zhao, Yanqing Liu and Hua Tian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:305

    Content type: Research article

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  42. This systematic review was conducted to gather available evidence on the effectiveness of muscle pedicle bone flap transplantation in adult patients with femoral neck fractures.

    Authors: Yipeng Wu, Muguo Song, Guangliang Peng, Yongqing Xu, Yang Li, Mingjie Wei, Hui Tang, Qian Lv, Teng Wang and Xingbo Cai

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:304

    Content type: Systematic review

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  43. Previous study showed that circular RNA Absent-Small-Homeotic-2--Like protein (circASH2L) was higher in rheumatoid arthritis (RA) patients. However, the roles and mechanisms of circASH2L in RA progression rema...

    Authors: Xia Li, Meiting Qu, Jie Zhang, Kuanyin Chen and Xianghui Ma

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:302

    Content type: Research article

    Published on:

  44. Congenital pseudoarthrosis of the clavicle (CPC) is an uncommon entity. Owing to its scarce presentation, treatment of this disorder has not been well established. This study aimed (1) to compare surgical trea...

    Authors: Jin Li, Sheng Ping Tang, Hai Bo Mei, Jing Fan Shao, Bao Jie Shi, Hai Qiang Wang and Xin Tang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:301

    Content type: Research article

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  45. To analyze the effect of sacrificing the posterior cruciate ligament (PCL) on the early postoperative outcome of cruciate retaining (CR) highly congruent rotating platform TKA.

    Authors: Long Chen, Jie Xu, Yuan Lin, Fen Qi Luo and Yu Guo Yu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:299

    Content type: Research article

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