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  1. Steroid-induced osteonecrosis of the femoral head (ONFH) is a common hip joint disease and is difficult to be diagnosed early. At present, the pathogenesis of steroid-induced ONFH remains unclear, and recogniz...

    Authors: Tianye Lin, Weijian Chen, Peng Yang, Ziqi Li, Qiushi Wei, Du Liang, Haibin Wang, Wei He and Qingwen Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:327
  2. Two minimally invasive approaches showed some advantages in outcomes compared to conventional approaches (CAs)—the direct anterior approach (DAA) and the supercapsular percutaneously assisted approach in THA (...

    Authors: Nikolai Ramadanov, Simon Bueschges, Kuiliang Liu, Philip Lazaru and Ivan Marintschev
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:324
  3. Patellofemoral pain is a common condition. The Kujala score is a well-established scoring system to assess anterior knee pain and has been translated into many languages including Arabic. The purpose of this c...

    Authors: Bassem I. Haddad, Mohammad Hamdan, Ula Isleem, Munther Ghassan Al-Saber, Fadi A. Al-Hadidi, Saif Aldeen AlRyalat and Fatima Alnaimat
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:323
  4. Greater trochanteric pain syndrome encompasses a range of causes of lateral hip pain including greater trochanteric bursitis, tendinopathy and tears of the gluteus minimus and medius, and lateral snapping hip ...

    Authors: Manuel Villanueva, Álvaro Iborra, Pablo Sanz-Ruiz and Concepción Noriega
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:322
  5. This study aimed to explore the correlation between the SRY-related high-mobility-group box gene 4 (SOX4) 3′ untranslated region (UTR) single nucleotide polymorphism (SNP) and osteoporosis susceptibility.

    Authors: Guo Li, Zuchao Gu, Yue He, Chongwen Wang and JiQiang Duan
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:321
  6. Anemia is common among ortho-geriatric hip fracture patients and is associated with prolonged recovery and increased postoperative mortality rate. Intravenous iron seems to increase hemoglobin recovery and red...

    Authors: Silas Zacharias Clemmensen, Kristian H. Kragholm, Dorte Melgaard, Lene T. Hansen, Johannes Riis, Christian Cavallius, Marianne M. Mørch and Maria Lukács Krogager
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:320
  7. Periprosthetic joint infection (PJI) is a serious complication of total joint arthroplasty. We performed a retrospective cohort study to evaluate (1) the change of coagulation profile in two-staged arthroplast...

    Authors: Hao Li, Rui Li, L. L. Li, Wei Chai, Chi Xu and Jiying Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:319
  8. Biochemical markers of bone turnover (BTMs), such as bone alkaline phosphatase (bALP), procollagen type I N propeptide (PINP), serum cross-linked C-telopeptides of type I collagen (bCTx), and urinary cross-lin...

    Authors: Filippo Migliorini, Nicola Maffulli, Filippo Spiezia, Markus Tingart, Peretti Giuseppe Maria and Giorgino Riccardo
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:318
  9. Fractures in the ankylotic spine may have an insidious presentation but are prone to displace with devastating consequences. The long lever arm of ankylosed spine fragments may lead to pulmonary and great vess...

    Authors: Rina E. Buxbaum, Adi Shani, Hani Mulla, Alon Rod and Nimrod Rahamimov
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:317
  10. There is great design variability on short femoral stems available on the market. This study aims to evaluate the short-term clinical and radiological results of two different design short femoral stems, both ...

    Authors: I. Tatani, K. Solou, A. Panagopoulos, J. Lakoumentas, A. Kouzelis and P. Megas
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:316
  11. Preoperative posterior tilt is a risk factor for fixation failure in femoral neck fractures. This study aimed to evaluate the configuration of anterior positioning screw in proximal femoral plating in the trea...

    Authors: Sheng-Bo Nie, Jun-Feng Liu, Jiang-Hua Zhu, Zi-Fei Zhou, Lei Zhang and Long-Po Zheng
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:315
  12. The extraction of a femoral stem during the revision hip arthroplasty can be a daunting task and can lead to catastrophic complications for the patient. A sound technique employed intraoperatively helps in the...

    Authors: Amit Singh, Sunirmal Mukherjee, Kuntal Patel, Deepak Herlekar, Srikant Gandavaram and Nicholas Charalambous
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:314
  13. Growing evidence has implicated core-binding factor beta (Cbfb) as a contributor to osteoblast differentiation, which plays a key role in fracture healing. Herein, we aimed to assess whether Cbfb affects osteo...

    Authors: Tuanmao Guo, Yanli Xing, Zhongning Chen, Xianhong Wang, Haiyun Zhu, Lan Yang and Yong Yan
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:313
  14. The purpose of this research is to evaluate the risk factors and incidence of pulmonary cement embolism (PCE) during percutaneous vertebroplasty (PVP) or kyphoplasty (PKP) for osteoporotic vertebral compressio...

    Authors: Dexin Zou, Shengjie Dong, Wei Du, Bing Sun and Xifa Wu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:312
  15. A recent genome-wide association study identified a susceptible locus in MIR4300HG gene that was associated with curve progression of adolescent idiopathic scoliosis (AIS) in the Japanese population. However, ...

    Authors: Yuwen Wang, Zhicheng Dai, Zhichong Wu, Zhenhua Feng, Zhen Liu, Xu Sun, Leilei Xu, Yong Qiu and Zezhang Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:311
  16. In fracture-related infections (FRI), both the diagnosis of the infection and the identification of the causative pathogen are crucial to optimize treatment outcomes. Sonication has been successfully used for ...

    Authors: Petri Bellova, Veronika Knop-Hammad, Matthias Königshausen, Thomas A. Schildhauer, Jan Gessmann and Hinnerk Baecker
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:310
  17. The purpose of this study was to determine whether the gap-balancing technique with patient-specific instrumentation (PSI) and a new balancing device in total knee arthroplasty (TKA) can improve knee function ...

    Authors: Ting Deng, Tangyou Liu, Qing Lei, Lihong Cai and Song Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:309
  18. Robot-assisted platforms in spine surgery have rapidly developed into an attractive technology for both the surgeon and patient. Although current literature is promising, more clinical data is needed. The purp...

    Authors: Nathan J. Lee, Ian A. Buchanan, Venkat Boddapati, Justin Mathew, Gerard Marciano, Paul J. Park, Eric Leung, Avery L. Buchholz, John Pollina, Ehsan Jazini, Colin Haines, Thomas C. Schuler, Christopher R. Good, Joseph M. Lombardi and Ronald A. Lehman
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:308
  19. Mounting evidence indicates that circular RNAs (circRNAs) participate in the occurrence and development of various diseases, including osteoarthritis (OA). However, the effects and molecular mechanism of circ_...

    Authors: Chao Liu, Ping Cheng, Jianjun Liang, Xiaoming Zhao and Wei Du
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:307
  20. The purpose of this study was to evaluate and compare the feasibility, safety, and efficacy of conventional open pedicle screw fixation (COPSF), percutaneous pedicle screw fixation (PPSF), and paraspinal poste...

    Authors: Chao Zhu, Bin Wang, Jian Yin and Xin Hui Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:306
  21. Soft tissue balancing is essential for the success of total knee arthroplasty (TKA) and is mainly dependent on surgeon-defined assessment (SDA) or a gap-balancer (GB). However, an electronic sensor has been de...

    Authors: Ran Zhao, Yanqing Liu and Hua Tian
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:305
  22. This systematic review was conducted to gather available evidence on the effectiveness of muscle pedicle bone flap transplantation in adult patients with femoral neck fractures.

    Authors: Yipeng Wu, Muguo Song, Guangliang Peng, Yongqing Xu, Yang Li, Mingjie Wei, Hui Tang, Qian Lv, Teng Wang and Xingbo Cai
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:304
  23. Previous study showed that circular RNA Absent-Small-Homeotic-2--Like protein (circASH2L) was higher in rheumatoid arthritis (RA) patients. However, the roles and mechanisms of circASH2L in RA progression rema...

    Authors: Xia Li, Meiting Qu, Jie Zhang, Kuanyin Chen and Xianghui Ma
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:302
  24. Congenital pseudoarthrosis of the clavicle (CPC) is an uncommon entity. Owing to its scarce presentation, treatment of this disorder has not been well established. This study aimed (1) to compare surgical trea...

    Authors: Jin Li, Sheng Ping Tang, Hai Bo Mei, Jing Fan Shao, Bao Jie Shi, Hai Qiang Wang and Xin Tang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:301
  25. To analyze the effect of sacrificing the posterior cruciate ligament (PCL) on the early postoperative outcome of cruciate retaining (CR) highly congruent rotating platform TKA.

    Authors: Long Chen, Jie Xu, Yuan Lin, Fen Qi Luo and Yu Guo Yu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:299
  26. We aimed to evaluate reliability, radiological outcomes, and the impacts of anterior cervical hybrid construction on the adjacent segments for the multilevel cervical degenerative disc disease (mCDDD) and spon...

    Authors: Murat Yilmaz, Kemal Yucesoy, Resat S. Erbayraktar and Rıfat S. Altinag
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:298
  27. Angiotensin II (Ang II) is associated with rheumatoid arthritis (RA) development. The present study investigated the impact of Ang II on the expression of receptor activator of nuclear factor-κB ligand (RANKL)...

    Authors: Zhiping Zhao, Yongtao Zhang, Changyao Wang, Xiangyu Wang, Yingzhen Wang and Haining Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:297
  28. To explore the impact of different repair methods for a lateral meniscus posterior root tear on the biomechanics of the knee joint using finite element analysis.

    Authors: Jian-Yu Wang, Yan-Song Qi, Hu-Ri-Cha Bao, Yong-Sheng Xu, Bao-Gang Wei, Yong-Xiang Wang, Bing-Xian Ma, Hui-Wen Zhou and Fei Lv
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:296
  29. In tibial plateau fractures (TPF) the restoration of an anatomical joint surface as well as an exact subchondral screw position for postoperative stability is crucial for the outcome.

    Authors: F. Souleiman, R. Henkelmann, J. Theopold, J. Fakler, U. Spiegl and P. Hepp
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:295
  30. Osteosarcoma is a disease with high mortality in children and adolescents, and metastasis is one of the important clinical features of osteosarcoma. N6-Methyladenosine (m6A) is the most abundant methylation modif...

    Authors: Hua Liu, Guangzhen Qin, Yanan Ji, Xiaojian Wang, Hailin Bao, Xiaojun Guan, Aichun Wei and Zhigang Cai
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:294
  31. Peritendinous adhesion is among the common complications after tendon injury. Numerous studies have been carried out to prevent its formation, including modifications of surgical procedures, postoperative care...

    Authors: Pengfei Li, Haiying Zhou, Tian Tu and Hui Lu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:293
  32. Culture-negative periprosthetic joint infections (PJIs) can complicate diagnosis and management of PJI. This study aimed to identify risk factors for culture-negative PJI and differences in clinical characteri...

    Authors: Shintaro Watanabe, Naomi Kobayashi, Akito Tomoyama, Hyonmin Choe, Etsuko Yamazaki and Yutaka Inaba
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:292
  33. Some unusual rotator cuff (RC) tears are located in more proximal tendinous portions, with substantial remnant tissue attached to the footprint. The two options for surgical repair are sacrificing or preservin...

    Authors: Hyung-Suk Choi, Byung-Ill Lee, Jae-Hyung Kim, Hyung-Ki Cho and Gi-Won Seo
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:291
  34. Osteoarthritis (OA) is a complex joint disease and chronic pain source, affecting a patient’s quality of life and posing a financial burden. As the dog is considered a nearly ideal species for translation rese...

    Authors: J. C. Alves, Ana Margarida Moniz Pereira dos Santos, Patrícia Jorge, Catarina Falcão Trigoso Vieira Branco Lavrador and L. Miguel Carreira
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:290
  35. Lateral tibial plateau fractures (TPFs) are often treated with conventional open reduction and internal fixation (ORIF) through standard anterolateral sub-meniscal arthrotomy. There has been increasing support...

    Authors: Xiangtian Deng, Hongzhi Hu, Yiran Zhang, Weijian Liu, Qingcheng Song, Xiaodong Cheng, Jian Zhu, Sifan Yang, Zhipeng Ye, Haitao Guan, Boyu Zhang, Zhanle Zheng and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:289
  36. The long pentraxin PTX3 is generating great interest given the recent discovery of its involvement in bone metabolism. This study investigates the role of circulating PTX3 as a marker of bone-related phenotype...

    Authors: Virginia Veronica Visconti, Chiara Greggi, Simona Fittipaldi, Donato Casamassima, Mariagrazia Tallarico, Francesco Romano, Annalisa Botta and Umberto Tarantino
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:288

    The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2021 16:331

  37. To describe a new technique for implanting a double-bundle titanium cable to treat acromioclavicular (AC) joint dislocation via the new guider, and evaluate clinic outcomes.

    Authors: Jun Wang, Yongfeng Cui, Yuhang Zhang and Hang Yin
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:287
  38. This study is to describe the design and surgical techniques of three- dimensional-printed porous implants for proximal giant cell tumors of bone and evaluate the short-term clinical outcomes.

    Authors: Yuqi Zhang, Minxun Lu, Li Min, Jie Wang, Yitian Wang, Yi Luo, Yong Zhou, Hong Duan and Chongqi Tu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:286
  39. To investigate the clinical efficacy of locking compression plate fixation for the treatment of femoral intertrochanteric fractures in patients with preexisting proximal femoral deformity.

    Authors: Shan Fan, Mingming Yin, Yibo Xu, Cheng Ren, Teng Ma, Yao Lu, Ming Li, Zhong Li and Kun Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:285
  40. To evaluate the effect of postoperative BP treatment on improving the fusion rate after lumbar spinal fusion surgery by performing a meta-analysis of randomized controlled trials (RCTs) and other comparative c...

    Authors: Jun Mei, Xiaoxu Song, Xiaoming Guan, Dou Wu, Junjie Wang and Qiang Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:284
  41. Platelet-rich plasma (PRP) has been used to favor anterior cruciate ligament (ACL) healing after reconstruction surgeries. However, clinical data are still inconclusive and subjective about PRP. Thus, we propo...

    Authors: Allan Felipe Fattori Alves, José Ricardo de Arruda Miranda, Sérgio Augusto Santana de Souza, Ricardo Violante Pereira, Paulo Roberto de Almeida Silvares, Seizo Yamashita, Elenice Deffune and Diana Rodrigues de Pina
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:283
  42. Osteoarthritis of the knee is a common degenerative joint disorder in our ageing population. A combination of thermal therapy with a self-management exercise have shown a positive effect in the management of o...

    Authors: Kevin Ki-Wai Ho, Anthony Wai-Leung Kwok, Wai-Wang Chau, S. M. Xia, Y. L. Wang and Jack Chun-Yiu Cheng
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:282
  43. Nonunion is a rare complication for distal fibular fractures. However, when there is a high degree of comminution, nonunion may occur. In this article, we describe a novel technique that uses the oblong hole o...

    Authors: Young Uk Park, Sung Jae Kim and Hyong Nyun Kim
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:281
  44. The overarching goal of our research was to compare the clinical and radiological outcomes with different sizes of cages implantation in anterior cervical discectomy and fusion (ACDF), and to evaluate the effe...

    Authors: Changyan Wu, Xiaojuan Yang, Xu Gao, Liwei Shao, Fang Li, Yunxin Sun, Xiaoyu Liu, Shuaihao Yao and Yifu Sun
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:280
  45. Curculigoside is a natural phenolic glycoside compound produced by Curculigo orchioides Gaertn. This study aimed to explore the effects of curculigoside in promoting the osteogenic differentiation of adipose-deri...

    Authors: Wei-Li You and Zheng-Long Xu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:279
  46. The association of the severity of clinical symptoms and level of functional performance with the degree of magnetic resonance imaging abnormalities in patients with lateral epicondylitis has not been fully el...

    Authors: Seok Woo Hong, Jeong-Hyun Kang, Jin Hun Park, Ji Na Kim, Hee Jin Park and Eugene Kim
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:278
  47. To explore the clinical efficacy of posterior LFF for cervical OPLL with radicular pain of upper limbs

    Authors: Bao Su, Jieliang Shen, Xiaoji Luo, Zhengxue Quan, Dianming Jiang, Xiaohua Peng and Ke Tang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:277
  48. Higher pedicle screw density posterior spinal fusion (PSF) constructs have not been shown to result in improved curve correction in Lenke 1 and 5 adolescent idiopathic scoliosis (AIS) but do increase cost. The...

    Authors: Timothy J. Skalak, Joel Gagnier, Michelle S. Caird, Frances A. Farley and Ying Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:276

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