Articles

Effect of unilateral pulsed jet lavage prior to vertebroplasty on the intravertebral pressure and cement distribution

Percutaneous vertebroplasty is the most common treatment for osteoporotic vertebral compression fracture. However, the morbidity of vertebroplasty-related complications, such as cement leakage, remains high. W...

Authors: Jun Yan, Qiaohui Liu, Yanping Zheng, Ziqun Liu, Xinyu Liu, Xun Guo, Penghui Liu, Peng Chen, Suomao Yuan, Yonghao Tian and Wanlong Xu

Intraoperative ultrasonography assistance for minimally invasive repair of the acute Achilles tendon rupture

Minimally invasive repair is a better option for Achilles tendon rupture with low re-rupture and wound-related complications than conservative treatment or traditional open repair. The major problem is sural n...

Authors: Yang Yongliang, Jia Honglei, Zhang Wupeng, Xu Shihong, Wang Fu, Wang Bomin, Li Qinghu, Wang Yonghui and Han Shumei

Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis: a single-center prospective randomized controlled study with a 1-year follow up

Osteoarthritis is the most prevalent type of arthritis, which significantly impacts the patient’s mobility and quality of life. Pharmacological treatments for osteoarthritis, such as corticosteroids, produce a...

Authors: Andrejs Elksniņš-Finogejevs, Luis Vidal and Andrejs Peredistijs

A comparison of EFECE systems with tension band wiring for patella fracture fixation in cadavers

EFECE systems are newly defined internal fixation systems, which are suitable for patella fracture fixation. The aim of this study was to compare the fixation strength of EFECE Systems with tension band wiring...

Authors: Emre Karadeniz and Elif Nedret Keskinoz

MiR-708 inhibits MC3T3-E1 cells against H₂O₂-induced apoptosis through targeting PTEN

The dysregulation of proliferation and apoptosis plays a significant role in the pathogenesis of postmenopausal osteoporosis (PO). MicroRNAs play an important role in regulating apoptosis of MC3T3-E1 cells. Ho...

Authors: Wei Zhang, Sheng-Yu Cui, Hong Yi, Xin-Hui Zhu, Wei Liu and You-Jia Xu

MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7

To explore the effect of miR-920 on osteogenic differentiation of human bone mesenchymal stem cells (hBMSCs) and the possible mechanism.

Authors: Jun-pu Zha, Xiao-qing Wang and Jun Di

Pilot investigation into osteotome hard surface coating and cutting-edge degradation

Osteotomes are bone cutting tools commonly reused in orthopedic surgical procedures. Despite undergoing rigorous cleaning, visual inspection, and sterilization procedures between every use, the condition of th...

Authors: David E. White, Jim Bartley, Christopher Whittington, Lorenzo M. G. Garcia, Kaushik Chand and Celine Turangi

Finite element analysis of the initial stability of arthroscopic ankle arthrodesis with three-screw fixation: posteromedial versus posterolateral home-run screw

Arthroscopic ankle arthrodesis (AAA) is a standard surgical method for the treatment of advanced traumatic ankle arthritis and has become more popular due to its advantages. To fix the tibiotalar joint, the us...

Authors: Sen Wang, Jian Yu, Xin Ma, Dahang Zhao, Xiang Geng, Jiazhang Huang and Xu Wang

Meta-analysis in periprosthetic joint infection: a global bibliometric analysis

Periprosthetic joint infection (PJI) is the most serious complication of joint replacement surgery. Further comorbidities include bedsore, deep vein thrombosis, reinfection, or even death. An increasing number...

Authors: Cheng Li, Christina Ojeda-Thies, Chi Xu and Andrej Trampuz

Clinical observation of two bone cement distribution modes of percutaneous vertebroplasty in the treatment of thoracolumbar Kümmell’s disease

In recent years, percutaneous vertebroplasty (PVP) has provided a new option for the treatment of Kümmell’s disease (KD). This retrospective study aimed to investigate the differences in clinical characteristi...

Authors: Ji-Bin Chen, Ya-Ping Xiao, Dong Chen, Jian-Zhong Chang and Te Li

Patterns, management, and outcomes of traumatic pelvic fracture: insights from a multicenter study

Traumatic pelvic fracture (TPF) is a significant injury that results from high energy impact and has a high morbidity and mortality.

Authors: Husham Abdelrahman, Ayman El-Menyar, Holger Keil, Abduljabbar Alhammoud, Syed Imran Ghouri, Elhadi Babikir, Mohammad Asim, Matthias Muenzberg and Hassan Al-Thani

Single versus dual orthogonal plating for comminuted midshaft clavicle fractures: a biomechanics study

Dual orthogonal plating of clavicle fractures may provide greater stiffness and strength than unilateral plate constructs and allow the use of lower-profile plates. We aim to biomechanically compare three clav...

Authors: Glenn N. Boyce, Andrew J. Philpott, David C. Ackland and Eugene T. Ek

Biomechanical study of a low-cost external fixator for diaphyseal fractures of long bones

External fixation improves open fracture management in emerging countries. However, sophisticated models are often expensive and unavailable. We assessed the biomechanical properties of a low-cost external fix...

Authors: Kouamé Jean-Eric Kouassi, Olivier Cartiaux, Loic Fonkoué, Christine Detrembleur and Olivier Cornu

One additional shot of brachial plexus block equates to less postoperative pain for younger children with elbow surgeries

Postoperative pain in children has always been inadequately evaluated. This study aims to evaluate the postoperative pain response using an additional dose of brachial plexus block (BPB) for younger children r...

Authors: Jin Li, Saroj Rai, Ruikang Liu, Ruijing Xu and Pan Hong

Assessment of grip-motion characteristics in carpal tunnel syndrome patients using a novel finger grip dynamometer system

Grip strength measurement is widely used in daily medical practice, and it has been reported that the grip strength decreases in patients with carpal tunnel syndrome (CTS). However, conventional grip dynamomet...

Authors: Toru Sasaki, Koji Makino, Akimoto Nimura, Shiro Suzuki, Tomoyuki Kuroiwa, Takafumi Koyama, Atsushi Okawa, Hidetsugu Terada and Koji Fujita

Design a novel integrated screw for minimally invasive atlantoaxial anterior transarticular screw fixation: a finite element analysis

To design a new type of screw for minimally invasive atlantoaxial anterior transarticular screw (AATS) fixation with a diameter that is significantly thicker than that of traditional screws, threaded structure...

Authors: Yingkai Zhang, Cheng Li, Lei Li, Yanyan Sun, Zeqing Li, Yunli Mei and Xinyuan Feng

Cervical sagittal alignment in adolescent high dysplastic developmental spondylolisthesis: how does the cervical spine respond to the reduction of spondylolisthesis?

Although pelvic and related parameters have been well stated in lumbar developmental spondylolisthesis, cervical sagittal alignment in these patients is poorly studied, especially in high dysplastic developmen...

Authors: Xinhu Guo, Weishi Li, Zhongqiang Chen, Zhaoqing Guo, Qiang Qi, Yan Zeng, Chuiguo Sun and Woquan Zhong

Effect of lesser trochanter posteromedial wall defect on the stability of femoral intertrochanteric fracture using 3D simulation

This study investigated the effects of posteromedial fracture fragments on the postoperative stability of intertrochanteric fractures of the femur by analyzing the quantity and range of fragments in CT 3D reco...

Authors: Hanru Ren, Rongguang Ao, Lianghao Wu, Zheng Jian, Xinhua Jiang and Baoqing Yu

Relationship between the inflammation/immune indexes and deep venous thrombosis (DVT) incidence rate following tibial plateau fractures

To determine the relationship between inflammation/immune-based indexes and deep venous thrombosis (DVT) incidence rate following tibial plateau fractures

Authors: Dawei Liu, Yanbin Zhu, Wei Chen, Junyong Li, Kuo Zhao, Junzhe Zhang, Hongyu Meng and Yingze Zhang

Circular RNA atlas in osteoclast differentiation with and without alendronate treatment

Alendronate (AL) is the most widely used bisphosphonate in the treatment of osteoporosis (OP). However, the role of circular RNAs (circRNAs) in the treatment of OP with AL remains unclear.

Authors: Jianbiao Lin, Shaofeng Ma, Cong Zhu, Changqing Chen, Weibin Lin, Canbin Lin, Guofeng Huang and Zhenqi Ding

Subchondral pressures and perfusion during weight bearing

Joints withstand huge forces, but little is known about subchondral pressures and perfusion during loading. We developed an in vitro calf foot model to explore intraosseous pressure (IOP) and subchondral perfu...

Authors: Michael Beverly, Barbara E. Marks and David W Murray

Osteonecrosis of femoral head in young patients with femoral neck fracture: a retrospective study of 250 patients followed for average of 7.5 years

To investigate the risk factors for osteonecrosis of the femoral head (ONFH) after the treatment of femoral neck fracture in patients under 60 years old.

Authors: Fang Pei, Rui Zhao, Fenglei Li, Xiangyang Chen, KaiJin Guo and Liang Zhu

miR-1323 suppresses bone mesenchymal stromal cell osteogenesis and fracture healing via inhibiting BMP4/SMAD4 signaling

Atrophic non-union fractures show no radiological evidence of callus formation within 3 months of fracture. microRNA dysregulation may underlie the dysfunctional osteogenesis in atrophic non-union fractures. H...

Authors: Hui Xie, Ming Liu, Yaofeng Jin, Haiqing Lin, Yushan Zhang and Song Zheng

Correction to: The one-in-all diagnostic value of 99mTcMDP bone scan combining with singlephoton emission tomography (SPECT)/CT imaging in spinal osteoblastoma

An amendment to this paper has been published and can be accessed via the original article.

Authors: Wenhui Ma, Zhiyong Quan, Jing Wang, Xiangdong Li and Guoquan Li

The effect of paraspinal muscle on functional status and recovery in patients with lumbar spinal stenosis

To investigate the association of paraspinal muscle quantity and quality with functional status in patients with lumbar spinal stenosis (LSS) and explore whether degeneration of paraspinal muscle could predict...

Authors: Wei Wang, Zhuoran Sun, Weishi Li and Zhongqiang Chen

Factors associated with the burden of family caregivers of elderly patients with femoral neck fracture: a cross-sectional study

This study aimed to study the factors associated with caregiver burden among caregivers of elderly patients with femoral neck fracture.

Authors: Peifen Xiao and Yongchun Zhou

Locking plate versus external fixation in the treatment of displaced femoral supracondylar fracture in children

Displaced supracondylar femoral fractures (SFF) are difficult injuries to treat in children. Several techniques have been widely used but few studies have compared the merits and drawbacks of each surgical int...

Authors: Jin Li, Xikai Guo, Hai Qiang Wang, Changjie Yue, Kailei Chen, Jiewen Ma, Jing Wang and Xin Tang

A novel protection liner to improve graft-tunnel interaction following anterior cruciate ligament reconstruction: a finite element analysis

Deteriorated bone-graft interaction at the tunnel entrance following ACL reconstruction (ACLR) is considered one of the primary causes of long-term tunnel enlargement and graft wear. Methods have been introduc...

Authors: Huizhi Wang, Min Zhang and Cheng-Kung Cheng

Direct anterior versus posterolateral approaches for clinical outcomes after total hip arthroplasty: a systematic review and meta-analysis

The main objective of our study was to compare the intraoperative and postoperative outcomes of direct anterior approach (DAA) with posterolateral approaches (PLA).

Authors: Wang Chen, Jian-Ning Sun, Ye Zhang, Yu Zhang, Xiang-Yang Chen and Shuo Feng

Clinical effect of intramuscular calcitonin compared with oral celecoxib in the treatment of knee bone marrow lesions: a retrospective study

Bone marrow lesions (BMLs) are a common finding in patients with osteoarthritis (OA), which are predictors of progression and pain related to cartilage damage in OA. The objective of the present research was t...

Authors: Jiaming Zhou, Wuyi Xiong, Pengguo Gou, Zhao Chen, Xing Guo, Xiaoyang Huo and Yuan Xue

The utility of ¹⁸F-FDG PET and PET/CT in the diagnosis and staging of chondrosarcoma: a meta-analysis

Chondrosarcoma is the second most common primary bone sarcoma; however, unlike other tumors, the biopsy cannot easily make a definite diagnosis or predict the histological grade. This meta-analysis was perform...

Authors: Qingyu Zhang, Yongming Xi, Dong Li, Zenong Yuan and Jun Dong

Identification of a potential gene target for osteoarthritis based on bioinformatics analyses

Osteoarthritis (OA) is the most common chronic joint disease worldwide. It is characterized by pain and limited mobility in the affected joints and may even cause disability. Effective clinical options for its...

Authors: Zhi-xi Duan, Yu-sheng Li, Chao Tu, Peng Xie, Yi-han Li, Lin Qi and Zhi-hong Li

Morphological parameters of fourth lumbar spinous process palpation: a three-dimensional reconstruction of computed tomography

The localization of lumbar fourth spinous process (L4-SP) is an important anatomical landmark, and identifying its accurate position is essential for the diagnosis and treatment of waist diseases.

Authors: Qi Feng, Lei Zhang, Mengyao Zhang, Youliang Wen, Ping Zhang, Yi Wang, Yan Zeng and Junqiu Wang

URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway

Osteosarcoma is one of the most common malignant bone tumors with the annual global incidence of approximately four per million. Upregulated gene 4 (URG4) expression in the osteosarcoma tissue is closely assoc...

Authors: Yayun Liu, Yizhe Xi, Gang Chen, Xidong Wu and Maolin He

Effect of symmetrical restoration for the migration of uncemented total hip arthroplasty: a randomized RSA study with 75 patients and 5-year follow-up

Inferior placement of a femoral stem is predictive for early loosening and failure, but does restoration of the original hip anatomy benefit the function and survival of a total hip replacement?

Authors: Sverrir Kiernan, Mats Geijer, Martin Sundberg and Gunnar Flivik

Repair of Achilles sleeve avulsion: a new transosseous suture technique

Achilles sleeve avulsion usually occurs from pre-existing insertional Achilles tendinopathy, leaving a calcific spur at the insertional site. The purpose of this study was to introduce a new technique using th...

Authors: Yu-ping Yang, Ding-yu Wang, Lin-wei Wei, Ning An, Li-yuan Tao, Chen Jiao, Qin-wei Guo and Yue-lin Hu

The influence of timing of surgery in the outcome of spinal cord injury without radiographic abnormality (SCIWORA)

Spinal cord injury without radiographic abnormality (SCIWORA) is a rare traumatic myelopathy. Although surgery is one of the most important treatments, the surgery for SCIWORA is controversial, especially the ...

Authors: Can Qi, Hehuan Xia, Dechao Miao, Xingui Wang and Zengyan Li

Melone’s concept revisited in comminuted distal radius fractures: the three-dimensional CT mapping

There is no consensus in the literature about the ideal classification of the distal radius fracture for the clinical practice. The traditional Melone classification system divides the distal radius into four ...

Authors: Shuang Li, Ying-Qi Zhang, Gu-Heng Wang, Kai Li, Jian Wang and Ming Ni

Minimally invasive far lateral debridement combined with posterior instrumentation for thoracic and lumbar tuberculosis without severe kyphosis

Anti-tuberculous therapy (ATT) alone cannot easily cure spine tuberculosis (STB) though it is the most essential treatment. Many studies have confirmed the efficacy of the surgical treatment of STB through ant...

Authors: Wei Xiong, Bing Yu, Yao Zhang, Chunxiao Wang, Xiaojie Tang, Haifei Cao, Xibing Zhang, Qinyong Song, Fang Tan and Jiangwei Tan

Modic changes of the lumbar spine—their association with the lumbar sagittal parameters: A retrospective imaging study

The Lumbar sagittal parameters might be related to modic changes (MCs). However, studies on this topic have rarely been reported. The aim of this study was to identify the relationships between the lumbar sagi...

Authors: Xiaoping Mu, Wei Peng, Chengqiang Yu, Jian Xiong, Jianxun Wei, Yufu Ou and Chenglong Wang

Medical exercise therapy alone versus arthroscopic partial meniscectomy followed by medical exercise therapy for degenerative meniscal tear: a systematic review and meta-analysis of randomized controlled trials

To explore if medical exercise therapy (MET) alone is comparable to arthroscopic partial meniscectomy (APM) followed by MET for knee pain, activity level, and physical function in middle-aged patients with deg...

Authors: Jianxiong Ma, Hengting Chen, Aifeng Liu, Yuhong Cui and Xinlong Ma

Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement

Authors: Mingjin Zhong, Kan Ouyang and Wei Lu

Relationship between the lateral acromion angle and postoperative persistent pain of distal clavicle fracture treated with clavicle hook plate

The clavicular hook plate is an accepted surgical procedure for distal clavicle fractures. The relationship of the characteristics of the hook plate, acromioclavicular joint and acromion morphology, and clinic...

Authors: Kailun Wu, Xinlin Su, Stephen J. L. Roche, Michael F. G. Held, Huilin Yang, Robert N. Dunn and Jiong Jiong Guo

Free superficial circumflex iliac artery perforator flap with a single-pedicle bilobed design for pediatric multi-digit defect reconstruction

This paper describes imaging and anatomical features, in order to assess the feasibility of superficial circumflex iliac artery perforator (SCIP) flap with a single-pedicle bilobed design for multi-digit skin ...

Authors: Zhangcan Li, Dawei Zheng, Jian Zheng, Weiya Qi, Qiang Qi and Yunyun Liu

Comparing total hip arthroplasty and hemiarthroplasty for the treatment of displaced femoral neck fracture in the active elderly over 75 years old: a systematic review and meta-analysis of randomized control trials

Displaced femoral neck fractures (DFNF) are increasingly common in elderly patients. Hip arthroplasty, the recommended treatment of DFNF, consists of the total hip arthroplasty (THA) and hemiarthroplasty (HA)....

Authors: Yijun Liu, Xiaokun Chen, Peixun Zhang and Baoguo Jiang

Epidemiological characteristics of spinal cord injury in Northwest China: a single hospital-based study

While the cities in China in which spinal cord injury (SCI) studies have been conducted previously are at the forefront of medical care, northwest China is relatively underdeveloped economically, and the epide...

Authors: Zhi-Meng Wang, Peng Zou, Jun-Song Yang, Ting-Ting Liu, Lei-Lei Song, Yao Lu, Hao Guo, Yuan-Ting Zhao, Tuan-Jiang Liu and Ding-Jun Hao

Propionibacterium acnes induces cartilaginous endplate degeneration by promoting MIF expression via the NF-κB pathway

Propionibacterium acnes (P. acnes) is a novel pathogenic factor that contributes to cartilaginous endplate (CEP) degeneration. However, the underlying mechanism of P. acnes-induced CEP degeneration remains unclea...

Authors: Ying Zhang, Yuting Wang, Yanyan Yuan, Yeting Lin, Binbin Lin and Haiyan Zhou

Modified algorithm for managing postoperative osteomyelitis following fracture fixation with Cierny-Mader type

No standardized protocol has been suggested in the treatment of postoperative osteomyelitis following fracture fixation. Our team evaluates the clinical efficacy of the modified algorithm for managing postoper...

Authors: Yanbin Tan, Hang Li, Zhijun Pan and Qiang Zheng

The Saudi Spine Society guidelines on spinal surgery during the COVID-19 pandemic

Authors: Ahmed Alturkistany, Fahad H. Abduljabbar, Fahad Alhelal, Nayef Bin Dajim, Salahaddeen Khalifah, Faisal Konbaz, Sami Aleissa, Amro Al-habib, Maan Kattan, Yahya Alqahtani and Raheef Alatassi

Effect of Achilles tendon on kinematic coupling relationship between tarsal bones: a pilot finite element study

The procedure of percutaneous Achilles tenotomy (PAT) is an important component of the Ponseti method. However, few studies reported the influence of Achilles tendon on kinematic coupling relationship between ...

Authors: Song-Jian Li, Lei Tang, Li Zhao, Cheng-Long Liu and Yu-Bin Liu