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  1. The prevalence of anaemia in patients planned for total hip and knee arthroplasty is about 20%. Optimising pre-operative haemoglobin levels by iron supplementation has been shown to decrease transfusion rates,...

    Authors: Viju Daniel Varghese, David Liu, Donald Ngo and Suzanne Edwards
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:536
  2. Free flaps have been a useful modality in the management of lower extremity osteomyelitis particularly in limb salvage. This study aimed to determine the factors affecting the outcome of free flap reconstructi...

    Authors: Duy Quang Thai, Yeon Kyo Jung, Hyung Min Hahn and Il Jae Lee
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:535
  3. Lumbar disc herniation (LDH) is a common problem. When surgical treatment is required, the intervention is typically decompression without fusion. Successful return-to-work (RTW) is a standard expectation with...

    Authors: Lauren A. Protzer, Steven D. Glassman, Praveen V. Mummaneni, Mohamad Bydon, Erica F. Bisson, Mladen Djurasovic and Leah Y. Carreon
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:534
  4. Osteoporosis affects mostly postmenopausal women, leading to deterioration of the microarchitectural bone structure and low bone mass, with an increased fracture risk with associated disability, morbidity and ...

    Authors: Filippo Migliorini, Nicola Maffulli, Giorgia Colarossi, Jörg Eschweiler, Markus Tingart and Marcel Betsch
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:533
  5. The current surgical treatment of choice is the combination surgical technique, involving tibial intramedullary fixation to maintain the mechanical axis and mechanical stability of tibial pseudarthrosis. In tr...

    Authors: Yaoxi Liu, Ge Yang, Guanghui Zhu, Qian Tan, Jiangyan Wu, Kun Liu, Jin Tang and Haibo Mei
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:532
  6. Volar locking plating remains a popular method for the surgical management of distal radius fractures. Dorsal metaphyseal comminution (DMC) is a common fracture pattern which weakens the stability during fract...

    Authors: Xue-yang Gui, Zhao-hui Cheng, Hong-fei Shi, Yi-xin Chen, Jin Xiong, Jun-fei Wang, Xu-sheng Qiu and Zi-tao Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:530
  7. To develop the novel self-reported spine functional scale (SSFS) and conduct reliability and validity analysis, so that the public can better understand their own spine function in a more simple and scientific...

    Authors: Wei Li, Jie Ding, Xiujuan Hao, Wenjun Jiang, Hongqiang Song, Yanming Zhang and Yan Tan
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:529
  8. External fixator (EF) is a popular choice for open tibial fractures, but pin tract infection (PTI) and refracture are common complications. Elastic stable intramedullary nail (ESIN) has been reported in the tr...

    Authors: Pan Hong, Saroj Rai, Xin Tang, Ruikang Liu and Jin Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:528
  9. Preexisting severe cervical spinal cord compression is a significant risk factor in cervical hyperextension injury, and the neurological function may deteriorate after a slight force to the forehead. There are...

    Authors: Jian-jie Wang, Meng-lei Xu, Hui-zi Zeng, Liang-dong Zheng, Shi-jie Zhu, Chen Jin, Zhi-li Zeng, Li-ming Cheng and Rui Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:527
  10. This study compared the failure load of the femoral insertion site of the anterior cruciate ligament between different portions and knee flexion angles.

    Authors: Shohei Yamauchi, Kyohei Ishibashi, Eiji Sasaki, Shizuka Sasaki, Yuka Kimura and Yasuyuki Ishibashi
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:526
  11. Postmenopausal osteoporosis is characterized by an imbalance of bone resorption exceeding bone formation, resulting in a net loss of bone mass. Whether a menopause-related excess of iron contributes to the dev...

    Authors: Lu-lin Liu, Gong-wen Liu, Hui Liu, Kai Zhao and You-jia Xu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:525
  12. To investigate the necessity of nonstructural or structural intraarticular bone grafting in atlantoaxial facet joints via a posterior approach and the influence by the presence of basilar invagination (BI).

    Authors: Jun Zhu, Jian Wu, Keyu Luo, Zhong Wang, Huaijian Jin, Yufei Jin, Yingbo Wang, Mingyong Liu and Peng Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:524
  13. Osteosarcoma is one of the most common malignant neoplasms in children and adolescents. Studies have shown that metabolism-related pathways are vital for the development and metastasis of osteosarcoma. Long no...

    Authors: Xingyin Chen, Zhengyun Ye, Pan Lou, Wei Liu and Ying Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:523
  14. To explore the feasibility of sacral-2-alar (S2-alar) screw placement by measuring the length, diameter, and angle of the screw trajectory on computed tomography (CT).

    Authors: Yulin Zhao, Baisheng Yuan, Yijun Han and Binglei Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:522
  15. The aim of this study was to evaluate the influence of antirheumatic drug treatment on knee function of stiff knee patients after total knee arthroplasty (TKA).

    Authors: Cheng-Qi Jia, Xiao-Rui Guan, Zhi-Lai Zhao, Ji-Ying Chen and Xiang Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:521
  16. To evaluate the efficacy of ultra-early rehabilitation on elbow function after Slongo’s external fixation for supracondylar humeral fractures in older children and adolescents.

    Authors: Man He, Qian Wang, Jingxin Zhao and Yu Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:520
  17. Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating disease, and the risk factors associated with progression into collapse after core decompression (CD) remain poorly defined. Therefore, w...

    Authors: En-Ze Zhao, Zun-Han Liu, Wei-Nan Zeng, Zi-Chuan Ding, Zhen-Yu Luo and Zong-Ke Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:519
  18. The surgical outcomes of anterior cervical discectomy and fusion (ACDF) in female patients according to menopausal status remain unclear. The objective of this study was to investigate the differences in these...

    Authors: Xing-jin Wang, Hao Liu, Jun-bo He, Quan Gong, Ying Hong, Xin Rong, Chen Ding, Bei-yu Wang, Yi Yang and Yang Meng
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:518
  19. Currently, patient-reported outcome measures (PROMs) are the standard instruments used to compare arthroplasty results. Goodman et al. recently published a well-constructed scale with excellent psychometric pr...

    Authors: Julián Brañes, Maximiliano Barahona, Sebastián Carvajal, Rodrigo Wulf and Cristián Barrientos
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:517
  20. Musculoskeletal conditions are highly prevalent, and knee OA is most common. Current treatment modalities have limitations and either fail to solve the underlying pathophysiology or are highly invasive. To add...

    Authors: Ashim Gupta, Nicola Maffulli, Hugo C. Rodriguez, R. Justin Mistovich, Kristin Delfino, Craig Cady, Anne-Marie Fauser, Echo D. Cundiff, Marte A. Martinez and Anish G. Potty
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:514
  21. Direct anterior approach (DAA) has several advantages including shorter length of hospital stay, faster recovery, and better functional outcome while this approach may cause damage to the lateral femoral cutan...

    Authors: Ong-art Phruetthiphat, Vasin Sangthumprateep, Songpol Trakulngernthai, Noppadol Aegakkatajit, Thanainit Chotanaphuti and Malee Chanpoo
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:513
  22. Developmental dysplasia of the hip (DDH) is a highly prevalent hip disease among children. However, its pathogenesis remains unclear. MicroRNAs (miRNA) are important regulators of cartilage development. In a p...

    Authors: Rui Ding, Xijuan Liu, Jian Zhang, Jinghong Yuan, Sikuan Zheng, Xigao Cheng and Jingyu Jia
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:512
  23. Cannulated screws (CS) are one of the most widely used treatments for femoral neck fracture, however, associated with high rate of complications. In this study, we designed a new type of cannulated screws call...

    Authors: Kai Ding, Weijie Yang, Jian Zhu, Xiaodong Cheng, Haicheng Wang, Du Hao, Song Yinuo, Yanbin Zhu, Yingze Zhang, Wei Chen and Qi Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:511
  24. The occurrence of chemoresistance is a common problem in tumor treatment. Circular RNA (circRNA) has been confirmed to be related to tumor chemoresistance. However, the role and the underlying molecular mechan...

    Authors: Yumei Bai, Yanghua Li, Juan Bai and Yumei Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:510
  25. Pertrochanteric fractures of the femur in the elderly are very common. As the average age of the population increases, the incidence of such fractures also raises, resulting in high healthcare costs. The type ...

    Authors: Giuseppe Gargano, Nicola Poeta, Francesco Oliva, Filippo Migliorini and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:509
  26. Improved oncological and surgical measures now enable curative treatment of malignant lower extremity tumors in majority of cases. Complication rates associated with surgical resection of lower extremity tumor...

    Authors: Moritz von Salis-Soglio, Mohamed Ghanem, Christian Lycke, Andreas Roth and Georg Osterhoff
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:508
  27. The anterior cruciate ligament (ACL) has a key role as a dynamic stabilizer of the knee joints, and ACL dysfunction caused by traumatic or degenerative rupture accelerates osteoarthritis progression. Thus, it ...

    Authors: Masaru Idota, Shinya Ishizuka, Hideki Hiraiwa, Satoshi Yamashita, Hiroki Oba, Yusuke Kawamura, Takefumi Sakaguchi, Takahiro Haga, Takafumi Mizuno, Itaru Kawashima, Kanae Kuriyama and Shiro Imagama
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:507
  28. Open reduction internal fixation (ORIF) has long been the conventional procedure for managing displaced patella fracture. This surgical approach has certain drawbacks, which might affect clinical outcomes and ...

    Authors: Chun-Hong Lo and Chih-Hwa Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:506
  29. The femoral neck system (FNS) may be a valid alternative for treating femoral neck fractures, but few studies have compared the outcomes between FNS and cannulated cancellous screws. This study aimed to compar...

    Authors: Yunfeng Tang, Zhen Zhang, Limin Wang, Wei Xiong, Qian Fang and Guanglin Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:504
  30. Dimensional measurements have been implemented on a variety of entities in morphological studies of the sub-axial cervical vertebral endplate. Despite great progress, little information between the mid-sagitta...

    Authors: Long Wang, Hao T. Luo, Wei Lu, Xing Bo Cai, Chen Yu and Sheng Lu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:503
  31. Acute compartment syndrome (ACS) is an underestimated complication following tibial plateau fractures. Understanding predictors of ACS in the lower leg after a fracture of the tibial plateau may guide earlier ...

    Authors: Xiangtian Deng, Hongzhi Hu, Zhipeng Ye, Jian Zhu, Yiran Zhang and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:502
  32. The important functional role the rotator cuff (RC) and biceps play in the shoulder, the close anatomical relationship between them and the high incidence of injuries require an appropriate multidisciplinary t...

    Authors: Rocio Aldon-Villegas, Veronica Perez-Cabezas and Gema Chamorro-Moriana
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:501
  33. Heterotopic ossification (HO) represents pathological lesions that refer to the development of heterotopic bone in extraskeletal tissues around joints. This study investigates the genetic characteristics of bo...

    Authors: Zhanyu Yang, Delong Liu, Rui Guan, Xin Li, Yiwei Wang and Bin Sheng
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:499
  34. Finite element analysis (FEA) is an important tool during the spinal biomechanical study. Irregular surfaces in FEA models directly reconstructed based on imaging data may increase the computational burden and...

    Authors: Jingchi Li, Chen Xu, Xiaoyu Zhang, Zhipeng Xi, Shenglu Sun, Ke Zhang, Xiaoyang Fang, Lin Xie, Yang Liu and Yueming Song
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:498
  35. The purpose of this study was to evaluate and compare the long-term clinical outcomes between the total patellectomy and osteosynthesis with tension band wiring in patients with highly comminuted patella fract...

    Authors: Xiangtian Deng, Lian Zhu, Hongzhi Hu, Jian Zhu, Weijian Liu, Junzhe Zhang, Sifan Yang, Zhipeng Ye, Haitao Guan, Boyu Zhang, Xiaodong Cheng and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:497
  36. Calcium phosphate-based bone graft substitutes are used to facilitate healing in bony defects caused by trauma or created during surgery. Here, we present an injectable calcium phosphate-based bone void filler...

    Authors: Jacob T. Landeck, William R. Walsh, Rema A. Oliver, Tian Wang, Mallory R. Gordon, Edward Ahn and Colin D. White
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:496
  37. This study investigates whether three-dimensional (3D) printing-assisted revision total hip/knee arthroplasty could improve its clinical and radiological outcomes and assess the depth and breadth of research c...

    Authors: Rui Zhang, Jiajun Lin, Fenyong Chen, Wenge Liu and Min Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:495
  38. Myelomeningocele (MMC) is the most common and severe form of spina bifida and imposes a significant burden on patients and the healthcare system. Recently, the multidisciplinary management of MMC has become po...

    Authors: Parnian Shobeiri, Ana Presedo, Amirali Karimi, Sara Momtazmanesh, Fardis Vosoughi and Mohammad Hossein Nabian
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:494
  39. The aims of current study were to present the clinical outcomes in patients with pediatric tibia shaft fractures who were treated with unilateral external fixation combined with joystick for fracture reduction...

    Authors: Xinhui Wang, Zhe Zhang, Xizhi Hou, Bao Wang, Yongdong Li and Tao Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:493
  40. This study aimed to evaluate the clinical efficacy of femoral head and neck fenestration combined with autologous bone mixed with β-tricalcium phosphate porous bioceramic bone (light bulb procedure) through Or...

    Authors: Dawei Liang, Jia Pei, Leilei Zhang, Haonan Ling, Youwen Liu and Xiantao Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:492
  41. This study aimed to explore the epidemiological and microbiological characteristics of fracture-related infection (FRI), analyze the drug resistance characteristics of major pathogens, and provide timely and r...

    Authors: Baisheng Wang, Xiaoguang Xiao, Jingdong Zhang, Wenfeng Han, Salad Abdirahman Hersi and Xin Tang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:490
  42. This study was designed to compare the ultimate tensile strength and force to 2 mm gap formation among 50% partial, 75% partial, and complete circumferential epitendinous suture with a combination of 4-strand ...

    Authors: Thepparat Kanchanathepsak, Wilarat Wairojanakul, Sorasak Suppaphol, Ittirat Watcharananan, Panithan Tuntiyatorn and Tulyapruek Tawonsawatruk
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:489
  43. Total hip arthroplasty (THA) has been used for over five decades for treating hip osteoarthritis. THA is a surgical procedure associated with prolonged hospital length of stay (LOS). The aim of this study was ...

    Authors: Raul Frankllim de Carvalho Almeida, Humberto Oliveira Serra and Liszt Palmeira de Oliveira
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:488
  44. The correlations between patient characteristics and early postoperative functional performances after total knee arthroplasty have not been adequately studied. The purpose of this study was to clarify the eff...

    Authors: Yoshinori Ishii, Hideo Noguchi, Junko Sato, Ikuko Takahashi, Hana Ishii, Ryo Ishii, Kei Ishii and Shin-Ichi Toyabe
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:487

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