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Correction: ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells

Journal of Orthopaedic Surgery and Research volume 18, Article number: 972 (2023) Cite this article

The Original Article was published on 29 November 2023

Correction: Journal of Orthopaedic Surgery and Research (2023) 18:910 https://doi.org/10.1186/s13018-023-04406-z


Following publication of the original article [1], the authors identified an error in Fig. 1. The correct figure is given below.

Fig. 1
figure 1

Bioinformatic and immunohistochemical results for the detection of the differential expression of ARHGAP44 in osteosarcoma, correlation with tumor prognosis, and correlation with p53. A Differential gene analysis of GSE14359, as obtained using GEO database; B The expression level of ARHGAP44 in osteosarcoma tissues was higher than that in paracancerous tissues, p = 0.011; C Immunohistochemical results of ARHGAP44 in osteosarcoma tissue showing deeply stained brown–yellow nuclei, images were recorded using ×400 magnification; D Immunohistochemical positive expression of ARHGAP44 in paracancerous tissues was lower than that in tumor tissues, images were recorded using ×400 magnification; E Kaplan–Meier survival curves of patients with high and low ARHGAP44-expressing osteosarcoma, p = 0.0291; F ROC model for 1-, 3-, and 5-year survival in patients with high ARHGAP44 expression; G KM survival analysis established based on immunohistochemical results of clinical specimens, p = 0.0495; H TCGA database showing that ARHGAP44 expression in osteosarcoma was negatively correlated with p53, p = 2.04e−05, with a Spearman correlation coefficient of −0.26; I–J Western blotting results of ARHGAP44 expression in osteosarcoma and osteoblastic cell lines, * for p < 0.05, **for p < 0.01

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The original article [1] has been corrected.

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  1. Shizhe Li and Jiancheng Xue have contributed equally to this work and share first authorship.

Authors and Affiliations

  1. Department of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China

    Shizhe Li

  2. Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China

    Shizhe Li, He Zhang & Guanning Shang

  3. Medical Research Center, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China

    Jiancheng Xue

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  1. Shizhe Li
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  2. Jiancheng Xue
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Correspondence to Guanning Shang.

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Li, S., Xue, J., Zhang, H. et al. Correction: ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells. J Orthop Surg Res 18, 972 (2023). https://doi.org/10.1186/s13018-023-04454-5

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  • DOI: https://doi.org/10.1186/s13018-023-04454-5

Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X