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Correction: ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells

The Original Article was published on 29 November 2023

Correction: Journal of Orthopaedic Surgery and Research (2023) 18:910 https://doi.org/10.1186/s13018-023-04406-z


Following publication of the original article [1], the authors identified an error in Fig. 1. The correct figure is given below.

Fig. 1
figure 1

Bioinformatic and immunohistochemical results for the detection of the differential expression of ARHGAP44 in osteosarcoma, correlation with tumor prognosis, and correlation with p53. A Differential gene analysis of GSE14359, as obtained using GEO database; B The expression level of ARHGAP44 in osteosarcoma tissues was higher than that in paracancerous tissues, p = 0.011; C Immunohistochemical results of ARHGAP44 in osteosarcoma tissue showing deeply stained brown–yellow nuclei, images were recorded using ×400 magnification; D Immunohistochemical positive expression of ARHGAP44 in paracancerous tissues was lower than that in tumor tissues, images were recorded using ×400 magnification; E Kaplan–Meier survival curves of patients with high and low ARHGAP44-expressing osteosarcoma, p = 0.0291; F ROC model for 1-, 3-, and 5-year survival in patients with high ARHGAP44 expression; G KM survival analysis established based on immunohistochemical results of clinical specimens, p = 0.0495; H TCGA database showing that ARHGAP44 expression in osteosarcoma was negatively correlated with p53, p = 2.04e−05, with a Spearman correlation coefficient of −0.26; IJ Western blotting results of ARHGAP44 expression in osteosarcoma and osteoblastic cell lines, * for p < 0.05, **for p < 0.01


The original article [1] has been corrected.

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Correspondence to Guanning Shang.

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Li, S., Xue, J., Zhang, H. et al. Correction: ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells. J Orthop Surg Res 18, 972 (2023). https://doi.org/10.1186/s13018-023-04454-5

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