Clinicopathologic significance and prognostic value of circRNAs in osteosarcoma: a systematic review and meta-analysis

Table 4 Pooled hazard ratios of circRNAs on prognosis in osteosarcoma

Prognosis	Number of studies	Number of patients	Effect size			Heterogeneity		Sensitivity analysis	Publication bias
Prognosis	Number of studies	Number of patients	HR	95%CI	p value	I-square (%)	chi-square (p)	Sensitivity analysis	Begg (p)	Egger (p)
OS	36	2213	2.437	2.224–2.670	< 0.001	0.0%	0.992	Reliable	0.097	0.612
DFS	7	564	2.125	1.621–2.786	< 0.001	62.1%	0.015	Not reliable	0.293	0.136

CI confidence interval, DFS disease-free survival, HR hazard ratio, OS overall survival

ISSN: 1749-799X