- Research article
- Open Access
Influence of intraoperative conventional fluoroscopy versus cone beam CT on long-term clinical outcome in isolated displaced talar fractures
© The Author(s). 2019
- Received: 16 July 2018
- Accepted: 18 December 2018
- Published: 8 January 2019
The objective of the study was to compare the radiologic and clinical outcome of patients with an isolated displaced talus fracture treated intra-operatively with either conventional fluoroscopy or additional cone beam computed tomography (CT).
Conventional intraoperative fluoroscopy was performed in group 1 and cone beam CT was added in group 2. Clinical outcome was assessed using the Foot Function Index (FFI), American Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, and the Short-Form 12 (SF-12) survey. In addition, the Kellgren-Lawrence score using X-rays was determined.
Overall, 24 cases were examined (group 1: 8 cases; group 2: 16 cases), with a mean follow up of 6.66 years. The FFI (group 1: 28.85 ± 22.78; group 2: 14.96 ± 15.11 points; p = 0.768), the AOFAS (group 1: 69.00 ± 24.71; group 2: 78.79 ± 17.07 points; p = 0.438), and the physical and mental component of the SF-12 (group 1: 44.79 ± 12.55; group 2: 47.63 ± 10.69 points; p = 0.136) (group 1: 46.19 ± 9.72; group 2: 53.57 ± 8.51; p = 0.242) did not differ significantly. Osteoarthritis of the talonavicular, subtalar, and ankle joints assessed using the Kellgren-Lawrence score appeared to be minor in the cone beam CT group but did not show significant differences (p = 0.309; p = 0.663; p = 0.082 respectively).
Intraoperative cone beam CT in addition to conventional fluoroscopy might be beneficial in the operative treatment of talar fractures but a statistical significance could not be demonstrated.
- Talus fracture
- Cone beam CT
- Intraoperative imaging
- Computed tomography
Fractures of the talus are rare and constitute only less than 2% of all fractures [1, 2]. In most cases, high-energy trauma with axial stress accounts for these types of fractures but rotational low-energy injuries can also result in avulsions of the talus . Displaced fractures are treated operatively with either closed or open reduction and with a screw, K-Wire, or plate fixation . Due to the retrograde blood supply of the talar body, osteonecrosis or mal-union/nonunion after disruption of the anatomic arterial ring surrounding the talar head occur . An anatomic reduction and a stable fixation of the fracture need to be achieved to lower the rate of complications [6–8]. Intraoperative fluoroscopy to analyze fracture reduction of the talus is implemented in the standard workflow. Despite that, the evaluation of the reconstruction of all joint surfaces and the implant placement can be demanding with conventional fluoroscopy. However, even in complex talar fractures, the intraoperative analysis of the reduction and implant placement is often still evaluated with conventional fluoroscopy [9, 10]. Postoperative computed tomography (CT) is the gold standard to assess the surgical outcome. If necessary, an additional revision surgery is then performed. An intraoperative analysis with a cone beam CT to detect malreduction or insufficient implant placement was found to be advantageous in several anatomical regions [11–13]. Image quality of intraoperative cone beam CT was found to be reasonable for identifying implant placement and fracture reduction of the talus in clinical and cadaveric studies [14–17]. The impact of intraoperative 3D imaging on radiologic and clinical outcome in displaced talar fractures has not been previously published.
The aim of this retrospective cohort analysis was to compare the radiologic and clinical outcome of patients with an isolated displaced talar fracture examined intra-operatively with either conventional fluoroscopy or additional cone beam CT. The hypothesis was that the use of intraoperative cone beam CT leads to an improved reduction and therefore to a superior radiologic and clinical outcome.
Inclusion and exclusion criteria
Isolated displaced talar fracture
Trauma between January 2001 and December 2013
Follow-up ≥ 24 months
Age ≥ 18 years
Injury of the ipsilateral limb
Operative treatment with plate, bonegraft or K-Wire
The statistical analysis was performed using SPSS (Version 188.8.131.52, IBM, Armonk, New York, USA) and Microsoft Excel 2013 (Version 15.0.4779.1001, Microsoft, Redmond, USA). Patients from the two groups were compared based on the aforementioned parameters. The statistical significance level was set to p < 0.05. For ordinal and nominal type variables, a Chi-squared test or Fisher’s exact test was applied. Interval type variables were compared using the t test if distributed normally. The Mann-Whitney U test was used for other distributions. The influence of covariates was determined with an analysis of covariance (ANCOVA).
All procedures performed in the study involving human participants were in accordance with the ethical standards and was approved by the state ethics committee.
Demographic data and distributions of mechanism of injury and fracture classification
Cone beam CT
34.1 ± 11.1 years
41.8 ± 14.3 years
Consequences after utilization of intraoperative cone beam computed tomography
Correction of screw placement
Correction of reduction
The objective of the study was to analyze the radiologic and clinical outcome of patients with an isolated displaced talar fracture treated with either conventional fluoroscopy or additional cone beam CT intra-operatively. The hypothesis was that patients treated with intraoperative cone beam CT have a significant superior radiologic and clinical outcome. A tendency of the data toward the cone beam CT group is evident but a significant improvement of the clinical and radiological outcome cannot be conveyed from the results. Therefore, the hypothesis of the study is refused.
Intraoperative cone beam CT showed a beneficial impact on the clinical outcome of patients with calcaneal fractures . Seventy-seven patients were included in the study by Franke et al. detecting statistically significant differences in the American Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale between the groups.
The clinical outcome in the study was assessed with a clinical investigation (ROM), Foot Function Index, AOFAS Ankle-Hindfoot Scale, and the Short-Form 12 survey. The ROM did not reveal significant differences between the two groups and neither did the clinical surveys. However, the cone beam CT group did tend to exhibit superior results in ROM and all clinical tests. The score of the conventional fluoroscopy group (average 69.0 ± 24.7) in the AOFAS is comparable to publicized data by Sanders et al. (71 ± 19 points), Ohl et al. (67 points), and Liu et al. (72.8 ± 17.3 points) [9, 19, 20]. The cone beam CT group scored higher with 78.8 points. The clinical outcome of the patients lacks good and excellent results due to the exclusion of non-displaced talar fractures in this study, which generally have a superior prognosis .
Osteoarthritis of the ankle, subtalar, and talonavicular joints was detectable in almost all patients at least 2 years after trauma. Kellgren-Lawrence score grade 4 appeared to occur more frequently in the conventional fluoroscopy group with 33% in the subtalar/talonavicular joint and 50% in the ankle joint respectively. A strong tendency was evident (p = 0.082), but a significant difference to the cone beam CT group could not be detected. Several studies reveal a high rate of posttraumatic osteoarthritis in the adjacent joints after displaced talar fractures but omitted differentiating the grade according to the Kellgren-Lawrence score [9, 19, 20, 22, 23].
The rate of an osteonecrosis did not differ significantly between groups but revealed a high percentage of 57.9%. Similar results could be observed by Lindvall et al. and Hawkins [18, 24]. Cebesoy et al. proposed that fractures reduction might not influence the risk of avascular necrosis, especially after Hawkins type 2 and 3 fractures . Lindvall et al. consented to this view that in particular the severity of the injury itself, and not the fracture fixation, may be responsible for higher rates of osteonecrosis . Irrespective of this, intra-articular implant placement or insufficient reduction with steps and gaps of the joint surface are not favorable for the clinical outcome.
As the isolated fracture of the talus is a rare entity, since talar fractures are often accompanied by other injuries, the total number of patients considered in the study is small. This corresponds to the data published by Sanders et al. in a retrospective cohort study . Another limitation of the study is the follow-up rate of only 75%, although this is comparable with other studies [6, 18, 20, 22]. This low rate is partly due to the rare occurrence of the fracture and the consecutive long follow-up times, which makes contacting the patients more difficult. Furthermore, the usage of cone beam CT to analyze reduction and implant placement was not randomized but relied on the intraoperative surgeon’s assessment.
In this study, only closed fractures were examined. This can be explained by the inclusion criteria of an isolated fracture. Severe soft issue impairment is often accompanied with multiple injuries of the limb.
Due to intraoperative imaging, intra-articular implant placement could be excluded in the cone beam CT group. Efforts were made to avoid steps and gaps in the articular surface but sometimes these could not be eliminated due to fracture morphology.
The surgical treatment of displaced talar fractures continues to be challenging. Intraoperative cone beam CT additional to conventional fluoroscopy might be beneficial for the surgeon in the operative treatment even though the results of the study do not reveal a significant improvement of the clinical and radiologic outcome in the cone beam CT group. A larger cohort of this rare injury appears to be necessary to reveal statistical significant differences.
The research group had grants/grants pending and technical support from Siemens (Erlangen, Germany). Siemens had no involvement in the study design, collection, analysis and interpretation of data, the writing of the manuscript, and the decision to submit the manuscript for publication.
Availability of data and materials
The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.
SV wrote the manuscript. KS and BS did the measurements. MS, NB, and HK developed the concept and the modalities. NB carried out the statistical analysis. JF and PG supervised the study and assisted with the concept. All authors read and approved the final manuscript.
Ethics approval and consent to participate
Ethics approval was given (Committee of the Medical Association of Rhineland-Palatinate, Mainz, Germany, reference no. 837.271.15), and participants in this study gave written consent to participate.
Consent for publication
PG and JF are paid members of an advisory board for Siemens. SV, KS, BS, MS, NB, and HK declare that they have no competing interests.
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Summers NJ, Murdoch MM. Fractures of the talus: a comprehensive review. Clin Podiatr Med Surg. 2012;29:187–203. viiView ArticleGoogle Scholar
- Vallier HA, Nork SE, Benirschke SK, Sangeorzan BJ. Surgical treatment of talar body fractures. J Bone Joint Surg Am. 2003;85-A:1716–24.View ArticleGoogle Scholar
- Bell J, Warren M, Cotnoir S. Fracture of the lateral process of the talus. J Orthop Sports Phys Ther. 2017;47:579.View ArticleGoogle Scholar
- Dodd A, Lefaivre KA. Outcomes of Talar neck fractures: a systematic review and meta-analysis. J Orthop Trauma. 2015;29:210–5.View ArticleGoogle Scholar
- Mulfinger GL, Trueta J. The blood supply of the talus. J Bone Joint Surg Br. 1970;52:160–7.View ArticleGoogle Scholar
- Ebraheim NA, Patil V, Owens C, Kandimalla Y. Clinical outcome of fractures of the talar body. Int Orthop. 2008;32:773–7.View ArticleGoogle Scholar
- Thordarson DB. Talar body fractures. Orthop Clin North Am. 2001;32:65–77. viiiView ArticleGoogle Scholar
- Vallier HA. Fractures of the talus: state of the art. J Orthop Trauma. 2015;29:385–92.View ArticleGoogle Scholar
- Liu H, Chen Z, Zeng W, Xiong Y, Lin Y, Zhong H, Wu J. Surgical management of Hawkins type III talar neck fracture through the approach of medial malleolar osteotomy and mini-plate for fixation. J Orthop Surg Res. 2017;12:111.View ArticleGoogle Scholar
- Reissig J, Bitterman A, Lee S. Common foot and ankle injuries: what not to miss and how best to manage. J Am Osteopath Assoc. 2017;117:98–104.View ArticleGoogle Scholar
- Franke J, von Recum J, Suda AJ, Grutzner PA, Wendl K. Intraoperative three-dimensional imaging in the treatment of acute unstable syndesmotic injuries. J Bone Joint Surg Am. 2012;94:1386–90.View ArticleGoogle Scholar
- Franke J, Wendl K, Suda AJ, Giese T, Grutzner PA, von Recum J. Intraoperative three-dimensional imaging in the treatment of calcaneal fractures. J Bone Joint Surg Am. 2014;96:e72.View ArticleGoogle Scholar
- Vetter SY, Euler F, von Recum J, Wendl K, Grutzner PA, Franke J. Impact of intraoperative cone beam computed tomography on reduction quality and implant position in treatment of Tibial plafond fractures. Foot Ankle Int. 2016;37:977–82.View ArticleGoogle Scholar
- Euler E, Wirth S, Linsenmaier U, Mutschler W, Pfeifer KJ, Hebecker A. Comparative study of the quality of C-arm based 3D imaging of the talus. Unfallchirurg. 2001;104:839–46.View ArticleGoogle Scholar
- Kotsianos D, Wirth S, Fischer T, Euler E, Rock C, Linsenmaier U, Pfeifer KJ, Reiser M. 3D imaging with an isocentric mobile C-arm comparison of image quality with spiral CT. Eur Radiol. 2004;14:1590–5.View ArticleGoogle Scholar
- Richter M, Geerling J, Zech S, Goesling T, Krettek C. Intraoperative three-dimensional imaging with a motorized mobile C-arm (SIREMOBIL ISO-C-3D) in foot and ankle trauma care: a preliminary report. J Orthop Trauma. 2005;19:259–66.View ArticleGoogle Scholar
- Richter M, Zech S. Intraoperative 3-dimensional imaging in foot and ankle trauma-experience with a second-generation device (ARCADIS-3D). J Orthop Trauma. 2009;23:213–20.View ArticleGoogle Scholar
- Lindvall E, Haidukewych G, DiPasquale T, Herscovici D Jr, Sanders R. Open reduction and stable fixation of isolated, displaced talar neck and body fractures. J Bone Joint Surg Am. 2004;86-A:2229–34.View ArticleGoogle Scholar
- Ohl X, Harisboure A, Hemery X, Dehoux E. Long-term follow-up after surgical treatment of talar fractures: twenty cases with an average follow-up of 7.5 years. Int Orthop. 2011;35:93–9.View ArticleGoogle Scholar
- Sanders DW, Busam M, Hattwick E, Edwards JR, McAndrew MP, Johnson KD. Functional outcomes following displaced talar neck fractures. J Orthop Trauma. 2004;18:265–70.View ArticleGoogle Scholar
- Higgins TF, Baumgaertner MR. Diagnosis and treatment of fractures of the talus: a comprehensive review of the literature. Foot Ankle Int. 1999;20:595–605.View ArticleGoogle Scholar
- Elgafy H, Ebraheim NA, Tile M, Stephen D, Kase J. Fractures of the talus: experience of two level 1 trauma centers. Foot Ankle Int. 2000;21:1023–9.View ArticleGoogle Scholar
- Vallier HA, Nork SE, Barei DP, Benirschke SK, Sangeorzan BJ. Talar neck fractures: results and outcomes. J Bone Joint Surg Am. 2004;86-A:1616–24.View ArticleGoogle Scholar
- Hawkins LG. Fractures of the neck of the talus. J Bone Joint Surg Am. 1970;52:991–1002.View ArticleGoogle Scholar
- Cebesoy O, Karakurum G. Talar fractures and avascular necrosis. Are we underestimating the risk? Int Orthop. 2007;31:269.View ArticleGoogle Scholar