Osteotomy at the distal third of tibial tuberosity with LCP L-buttress plate for correction of tibia vara
© Huang et al.; licensee BioMed Central Ltd. 2014
Received: 4 September 2013
Accepted: 28 January 2014
Published: 13 February 2014
Many osteotomy methods and fixation types have been used to correct the misalignment observed in tibia vara and to achieve a more uniform distribution of weight across the knee joint.
The aim of this study is to test the efficacy and safety of a modified closing wedge high tibial osteotomy (CWHTO) procedure for tibia vara.
In this prospective study, young adults with tibia vara and mild medial arthritic changes were included. A CWHTO was performed at the distal third of the tibial tuberosity, instead of the conventional proximal site. An L-shaped locking compression plate was used for internal fixation. Before/after evaluation of femoro-tibial angle (FTA), pain relief, patellar height, and posterior tibial slope were evaluated. Adverse events were monitored.
Seventy-five knees from 46 patients aged 27.2 ± 5.8 years (range, 14–43 years) underwent the modified CWHTO procedure. After a follow-up of 26.3 ± 7.4 months (range, 15–46 months), FTA correction was 12.4° ± 4.7° (range, 7°–31°), and pain was relieved. Reduction in the posterior tibial slope was 3.0° ± 2.3° (p < 0.001), while there was no significant change in patella height. Bone union was observed in all patients. There were a delayed union in four knees, a peroneal nerve lesion in five knees causing partial paralysis and/or sensory loss, and infections in two knees. Three patients underwent a second surgery. All adverse events were successfully treated except for a case of extensor hallucis longus muscle paralysis.
The modified CWHTO procedure is efficient and safe for the correction of tibia vara in young patients.
Osteoarthritis of the knee is a common condition that may occur in young people. In cases of misalignment of the knee joint such as tibia vara, the medial compartment of the knee is submitted to abnormally high forces and weight loading that causes progressive wearing of the joint cartilage and further aggravates the varus deformity. This results in a vicious cycle, which ultimately leads to progressive osteoarthritis if the misalignment is not corrected .
Many methods of osteotomy and types of fixation have been used to correct the misalignment and to achieve a more uniform distribution of weight across the knee joint [2, 3]. Coventry  used a closing wedge osteotomy proximal to the tibial tuberosity, the so-called closing wedge high tibial osteotomy (CWHTO). Recently, new techniques for medial open-wedge high tibial osteotomy (OWHTO) have been popularized. Among these are the locking compression plates (LCP) that are widely used in OWHTO and provide superior initial stability [5–7].
Each method has its pros and cons, and specific considerations when selecting the patients are necessary. The disadvantages of medial OWHTO are that it affects the height of the patella [8–10], is associated with slower bone healing, and requires autograft when the opening width exceeds 13 mm; therefore, simultaneous bilateral osteotomies are not recommended . The disadvantages of CWHTO include adverse effects on patello-femoral (PF) biomechanics, and a limited correction capability . Therefore, for correcting severe deformities, particularly in young patients, there is a need for an osteotomy procedure that does not disturb PF kinematics, allows rapid healing, is possible without the need for a supplementary surgery for harvesting autogenous bone, and can be performed bilaterally simultaneously.
With an aim to meet the above requirements, we tested a modified CWHTO procedure. The modification is that the osteotomy was performed at the distal third of the tibial tuberosity, followed by insertion of an L-shaped LCP plate to facilitate fixation. The distal third of the tibial tuberosity was selected to avoid disturbing the patella tendon and in order to perform the surgery as proximally as possible to obtain a better healing potential in cancellous bone area. The present study aimed to answer two questions: (1) What is the efficacy of this modified approach in terms of correction angle, patella height, tibial slope, Insall-Salvati (IS) index and pain alleviation? (2) What is the safety of this modified approach in terms of consolidation, alignment, re-operation, infections, and neurologic complications? Safety was evaluated from the record of adverse events and complications that are known to occur after conventional CWHTO .
Materials and methods
The aim of this prospective study was to assess the efficacy and safety of a modified CWHTO procedure. The surgeries were performed between March 2008 and October 2010 at the Beijing Jishuitan Hospital, Beijing, China. The study was approved by the institutional review board of Beijing Jishuitan Hospital, Beijing, China, and all patients provided a written informed consent. We enrolled tibia vara patients with mild arthritic changes who were admitted for surgical correction of the misalignment. A modified procedure for tibial osteotomy was performed, and an L-shaped LCP plate was inserted for rigid fixation (described below). Patients were followed up for a maximum of 4 years. Standard clinical and radiological methods were used for diagnosis and for assessment of treatment outcomes in terms of limb alignment, pain relief, patella height, tibial slope change, bone healing, and complications.
The inclusion criteria were as follows: (1) patients younger than 45 years and (2) tibia vara deformity with mild medial-compartmental osteoarthritis. Exclusion criteria were as follows: (1) severe obesity (body mass index (BMI) >40.0 ), (2) loss of lateral meniscus, (3) degenerative joint disease in the lateral compartment, (4) limited range of motion of the knee (flexion contracture >10°), or (5) less than two thirds of the articular gap of the medial compartment, as observed by radiography [11, 14].
During surgery, the patient was placed in the supine position and a tourniquet was placed high on the thigh. A fibular osteotomy was performed through a 3–4-cm incision made over the lateral aspect of the leg at about 15 cm distal to the fibular head . The length of fibular resection was equal to or shorter than the base of the tibial osteotomy wedge.
The wires served to guide the bone cuts. We began the cuts using a saw under constant irrigation for cooling and then continued with the osteotome. The hinge of the medial cortex was carefully penetrated with the use of a drill instead of an osteotome (Figure 2C). The wedge was extracted completely, and we made sure that no fragment of cortical bone persisted in the posterior part of the osteotomy. The osteotomy was closed slowly and carefully. More than 90% of the hinge could be preserved.
The surgery was performed under fluoroscopic control. The frontal alignment was checked with a cautery cord. One end was placed over the center of the femoral head and the other over the center of the ankle, making sure that the cord was tight and straight. An adequate correction was achieved when the cord passed directly over the center of the knee (Figure 2D). The posterior slope of the tibia was also evaluated under fluoroscopy to prevent the introduction of an anterior slope or excessive slope angle alteration.
If the extracted wedge was too small, the osteotomy surface was cut again. In general, large wedge resection was avoided, but if it was done, the osteotomy gap was only partially closed to avoid overcorrection, and the gap was carefully filled with autograft of a cancellous bone from the resected tibial wedge after the fixation was completed. An L-shaped LCP was used for internal fixation. The plate (Synthes GmbH, Oberdorf, Switzerland) was made of pure titanium, 2.5-mm thickness, 16.0-mm width, and had four or five holes (shaft). The proximal part of the plate was placed at the level of Gerdy’s tubercle or immediately distal to it. The shaft was aligned to the longitudinal axis of the tibia, and the shaft end was attached to the bone surface distally. The plate’s position could be adjusted anteriorly or posteriorly. It was not necessary to bend it to adapt it to the bone surfaces. Three self-tapping 5.0-mm locking head screws were inserted as deep as possible in the proximal segment. In cases where the medial hinge was well-preserved, only two screws were used if the bone ends contacted well. Three more locking screws were inserted distally (Figure 2E).
After fixation, the tension of the intercompartmental septum between the anterior and lateral muscle compartments was assessed by palpation with a finger at the fibula incision. If the septum was tight and the proximal fibula was adducted, we recommend releasing the septum. After using an elevator to elevate the septum of the fibula from distal to proximal about 3–4 cm, we could free the fibula proximal end and place it in the correct position for bone healing. The tourniquet was released, and the wounds were closed. The fascia that covers the anterior tibialis muscle was released with scissors if it was tight after reattaching the anterior tibialis, and drainage was applied.
Postoperative procedures and follow-up
Patients operated in only one knee started isometric quadricep exercises on the first day and received immediate continuous passive motion (CPM) after drainage removal. Touchdown weight-bearing (15–20 kg) was allowed in the first 6 weeks. After 6 weeks, weight-bearing was increased by 10–15 kg per week. In cases where both knees were operated, weight-bearing was not allowed in the first 6–8 weeks. Patients were then provided with a wheelchair, and deep vein thrombosis (DVT) prophylaxis (compression stockings and warfarin for 4–5 weeks or less) was recommended. Partial weight-bearing was allowed only after 6–8 weeks. In most cases, full weight-bearing was allowed on the second follow-up at the 12th week, when radiographic consolidation had taken place. Follow-up was routinely performed on the 6th, 12th, 24th, and 52nd weeks after operation. Clinical and radiographic assessments were performed at each visit, and knee pain was evaluated using a visual analog scale (VAS). The fixation plate was usually removed 1 to 1.5 years after operation, upon patients’ request.
Standard AP and lateral radiographs of the knee joint and standing AP radiographs of the entire lower limbs were obtained pre- and postoperatively and were compared. FTA was measured on the AP knee radiograph, and the Mikulicz line was evaluated on the long film of the entire lower limbs. The posterior tibial slope was measured according to the method of Brazier et al.  on the true lateral view using the posterior tibial cortex as a reference. The posterior tibial cortex was easily identifiable on radiographs and was used as a reliable landmark for minimizing systematic error [20, 21]. IS index was also measured on the lateral radiographs preoperatively and at the last follow-up by measuring the ratio of patellar tendon length to the diagonal length of the patella .
SPSS 18.0 (SPSS Inc., Chicago, IL, USA) was used for statistical analysis. FTA, posterior tibial slope, and IS index pre- and postsurgery were compared using paired t tests. A p value <0.05 was considered statistically significant.
Patient characteristics at baseline
Baseline patients’ characteristics
Age, years (mean ± SD, range)
27.2 ± 5.8, 14–43
Body mass index (mean ± SD, range)
21.7 ± 3.2, 18.2–30.1
FTA (mean ± SD, range)a
186.2° ± 5.1°, 179°–209°
Mechanical distal lateral femoral angle (mean ± SD, range)a
87.4° ± 2.2°, 84°–91°
Mechanical medial proximal tibial angle (mean ± SD, range)a
75.8° ± 5.4°, 53°–83°
Requiring single knee operation, n
17 (17 knees)
Requiring bilateral operation, n
29 (58 knees)
What is the efficacy of this modified approach in terms of correction angle, patella height, tibial slope, IS index, and pain alleviation?
Comparison of relevant parameters before and after the modified CWHTO in patients with tibia vara
Femorotibial angle (range)
186.2° ± 5.1° (179° to 209°)
173.3° ± 2.0° (170° to 178°)
2.35 ± 1.6
0.56 ± 1.0
Posterior tibial slope (range)
5.9° ± 2.4° (0° to 11°)
2.8° ± 1.9° (−3° to 7°)
Insall-Salvati index (range)
1.03 ± 0.13 (0.8 to 1.3)
1.02 ± 0.14 (0.8 to 1.3)
What is the safety of this modified approach in terms of consolidation, alignment, re-operation, infections, and neurologic complications?
There was delayed union in four knees in three patients. In three cases, full weight-bearing was not allowed for 6–9 months postsurgery, until radiographic consolidation was observed. One knee was re-operated on the sixth postoperative month, because the patient thought the affected knee was more valgus than desired and that the appearance was asymmetric. In this patient, the alignment was adjusted, the osteotomy site was autografted with cancellous bone from the iliac crest, and the fixation was revised. The bone healed as expected. Infections occurred in two knees (2.6%), which were treated with debridement and external skeletal fixation. The infections were controlled, and the corrected alignment was maintained. Peroneal nerve complications occurred in five knees. Two patients had paralysis of the dorsiflexion muscles innervated by the common peroneal nerve (tibialis anterior, extensor digitorium longus, and extensor hallucis longus in the anterior compartment). Full recovery occurred at 6 months. Sensory loss alone occurred in two knees, both of which recovered within 3–6 months. One patient had extensor hallucis longus muscle paralysis. She did not recover at the latest follow-up (15 months postsurgery).
The patients selected for the present study had several characteristics that prompted us to modify the CWHTO procedure rather than following the conventional CWHTO or OWHTO. Most of the included patients were young and active, requiring avoiding any ill-effects on PF kinematics that are often reported in OWHTO and conventional CWTHO. Thirty-five of 75 knees had more than 13° varus deformity. According to the Hernigou trigonometric chart , in OWHTO, the open wedge gap would have been more than 13 mm, which would have required harvesting an autograft from the iliac crest . Twenty-four of 29 patients with bilateral deformities expected simultaneous bilateral operation. This is not recommended in OWHTO because of the risk of secondary loss of correction caused by overloading on the bones that consolidate slowly . Hence, we modified the conventional CWTHO procedure to meet the requirements of this group of patients and tested its efficacy and safety.
What is the efficacy of this modified approach in terms of correction angle, patella height, tibial slope, IS index, and pain alleviation?
In this study, the correction was accurate, as seen from the postoperative FTA (mean, 173.3° ± 2.0°, range, 170°–178°) (Table 2). In elderly patients with progressive osteoarthritis, the alignment usually requires an overcorrection, such that the weight-bearing axis passes through a point located lateral on the tibia plateau by the Fujisawa scale . Such a degree of valgus alignment is unacceptable in young patients who expect a normal appearance and full activity. Hence, we tried to achieve minimal overcorrection with the Mikulicz line passing through the center of the knee. Most patients have been relieved of their preoperative pain. The long-term results of the affected knees need to be followed up and studied in the future.
Stoffel et al.  compared medial open wedge osteotomies that were either distal or proximal to the tuberosity and found that PF contact stress was significantly lower in the distal osteotomy group. The osteotomy site in the modified CWHTO procedure was distal to the tuberosity. The difference in the IS index before (1.03 ± 0.13) and after (1.02 ± 0.14) the operation was not statistically significant. Thus, this procedure did not change the patellar height. In the present study, all cases had minimal cartilage loss in the medial compartment. The rigid internal fixation and early mobilization of the knee used in this procedure also contributed to the preservation of normal PF kinematics.
Both open and closing wedge osteotomies primarily involve the frontal plane but also affect the posterior tibial slope. CWHTO is known to reduce the tibial slope by approximately 5° . In the present study, the average reduction in posterior slope was 3.0° ± 2.3°. However, if the tibial slope changes less than 5°, it does not significantly alter the in situ forces on the cruciate ligament [26, 27]. The smaller effect (average 3°) on posterior tibial slope might be because it is different from the triangle geometry at the conventional osteotomy site , as the lateral cortex of tibia is more parallel to the sagittal plane at the level of the distal third of tuberosity. When the wedge is resected, the anterior and posterior closures on the sagittal plane are almost equal, and the slope changes little. Fluoroscopic examination also helped to assess the slope change after wedge closing. It is important to note that the amount of bone resected was equal anteriorly and posteriorly, making it prone to anterior sloping. Therefore, a careful X-ray monitoring should be performed.
What is the safety of this modified approach in terms of consolidation, alignment, re-operation, infections, and neurologic complications?
Compared with a conventional CWHTO or OWHTO, the osteotomy site was more distal in the present study. The usual concern when an osteotomy is made at this level is a risk of a delayed bone union or non-union , which was not the case in the present study. Indeed, radiographic consolidation was observed within 3 months in most patients in our study. There are several reasons to explain this high union rate. Because all included patients were young (average age about 27 years), they presumably had a greater healing potential, and the soft tissues surrounding the osteotomy site were strong. The osteotomy site was as proximal as possible, although not above, the tibial tuberosity. At this site, two broad cancellous surfaces retain an excellent healing potential when they are in a stable, direct apposition. The technical factors that are likely to have contributed to the high union rate include avoidance of complete fracture of the medial cortex and retaining the medial soft tissue hinge intact. With the stable medial hinge, the locking plate can provide stable initial fixation. We also autografted the osteotomy site with cancellous bone from the resected tibial wedge if there was a gap.
Many studies have reported good outcomes of using an LCP in OWHTO . The use of an LCP in CWHTO also provided reliable fixation in the present study. There was no secondary correction loss in postoperative alignment in any patient. The LCP also simplified the fixation process. It is unnecessary to bend the plate for implant contouring, because the principle of the locking plate does not require form-fit seating on the bone. The proximal screws at the level of Gerdy’s tubercle allowed the soft tissues close to the joint capsule to be kept intact, including the attachment of the iliotibial band. The screws were distant enough from the joint to prevent articular penetration.
Peroneal nerve lesion occurred in 5 out of 75 operated knees, due to the fibula osteotomy that is part of this modified CWHTO procedure. In our experience, patients with more severe tibia vara deformity, especially those who have greater tibia torsion, are at higher risk of peroneal nerve palsy. The nerve may be injured by entrapment in the intercompartmental septum between the anterior and lateral muscle compartments or due to high tension in the compartmental fascia. We selected the site of the fibular osteotomy in the middle portion of the fibular shaft (15 cm distal to the fibula head ) to prevent injury of the common peroneal nerve and its branches. In cases of serious deformity, the intercompartmental septum could be twisted after correction, because our osteotomies on tibia and fibula were not on a same level. The high tension caused by the swelling of the muscles and the hematoma in the anterior compartment could not be released, which probably caused nerve injury or a kind of anterior compartmental syndrome. Therefore, we strongly recommend verifying the tension in the intercompartmental septum by touch. If the septum is tight and the proximal fibula is stuck in an adducted position, we can elevate the septum and free the proximal end of the fibular bone. In addition, we also recommend releasing the fascia that covers the anterior tibialis muscle with scissors if it is tight after suturing the attachment of the anterior tibialis.
In conclusion, the modified CWHTO procedure described in the present study, in which the osteotomy was performed at the level of the distal third of the tibia tuberosity, was found to be safe and effective in correcting the varus deformity, relieving pain and preserving PF kinematics. Compared with OWHTO, complications of a fibula resection is still a concern. This procedure may be used for young and active patients with low to severe tibia vara, both uni- or bilateral, and low to mild OA. In future studies, a longer follow-up may be included to study the long-term activity and function of the affected joints.
- McKellop HA, Llinas A, Sarmiento A: Effects of tibial malalignment on the knee and ankle. Orthop Clin North Am. 1994, 25: 415-423.PubMedGoogle Scholar
- Jackson JP, Waugh W: Tibial osteotomy for osteoarthritis of the knee. J Bone Joint Surg Br. 1961, 43-B: 746-751.PubMedGoogle Scholar
- Jackson JP, Waugh W: The technique and complications of upper tibial osteotomy. A review of 226 operations. J Bone Joint Surg Br. 1974, 56: 236-245.PubMedGoogle Scholar
- Coventry MB: Osteotomy of the upper portion of the tibia for degenerative arthritis of the knee. A preliminary report. J Bone Joint Surg Am. 1965, 47: 984-990.PubMedGoogle Scholar
- Moreland JR, Bassett LW, Hanker GJ: Radiographic analysis of the axial alignment of the lower extremity. J Bone Joint Surg Am. 1987, 69: 745-749.PubMedGoogle Scholar
- Sommer C, Gautier E, Muller M, Helfet DL, Wagner M: First clinical results of the locking compression plate (LCP). Injury. 2003, 34 (Suppl 2): B43-B54.View ArticlePubMedGoogle Scholar
- Staubli AE, De Simoni C, Babst R, Lobenhoffer P: TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia—early results in 92 cases. Injury. 2003, 34 (Suppl 2): B55-B62.View ArticlePubMedGoogle Scholar
- Smith TO, Sexton D, Mitchell P, Hing CB: Opening- or closing-wedged high tibial osteotomy: a meta-analysis of clinical and radiological outcomes. Knee. 2011, 18: 361-368. 10.1016/j.knee.2010.10.001.View ArticlePubMedGoogle Scholar
- Brouwer RW, Bierma-Zeinstra SM, van Koeveringe AJ, Verhaar JA: Patellar height and the inclination of the tibial plateau after high tibial osteotomy. The open versus the closed-wedge technique. J Bone Joint Surg Br. 2005, 87: 1227-1232.View ArticlePubMedGoogle Scholar
- Fan JC: Open wedge high tibial osteotomy: cause of patellar descent. J Orthop Surg Res. 2012, 7: 3-10.1186/1749-799X-7-3.PubMed CentralView ArticlePubMedGoogle Scholar
- Brinkman JM, Lobenhoffer P, Agneskirchner JD, Staubli AE, Wymenga AB, van Heerwaarden RJ: Osteotomies around the knee: patient selection, stability of fixation and bone healing in high tibial osteotomies. J Bone Joint Surg Br. 2008, 90: 1548-1557.View ArticlePubMedGoogle Scholar
- Tunggal JA, Higgins GA, Waddell JP: Complications of closing wedge high tibial osteotomy. Int Orthop. 2010, 34: 255-261. 10.1007/s00264-009-0819-9.PubMed CentralView ArticlePubMedGoogle Scholar
- Bei-Fan Z, Cooperative Meta-Analysis Group of Working Group on Obesity in C: Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults: study on optimal cut-off points of body mass index and waist circumference in Chinese adults. Asia Pac J Clin Nutr. 2002, 11 (Suppl 8): S685-S693.View ArticleGoogle Scholar
- Fujisawa Y, Masuhara K, Shiomi S: The effect of high tibial osteotomy on osteoarthritis of the knee. An arthroscopic study of 54 knee joints. Orthop Clin North Am. 1979, 10: 585-608.PubMedGoogle Scholar
- Ahlbäck S: Osteoarthrosis of the knee. A radiographic investigation. Acta Radiol Diagn (Stockh). 1968, 7-72. Suppl 277Google Scholar
- Paley D, Pfeil J: Principles of deformity correction around the knee. Orthopade. 2000, 29: 18-38.PubMedGoogle Scholar
- Miniaci A, Ballmer FT, Ballmer PM, Jakob RP: Proximal tibial osteotomy. A new fixation device. Clin Orthop Relat Res. 1989, 246: 250-259.PubMedGoogle Scholar
- Kirgis A, Albrecht S: Palsy of the deep peroneal nerve after proximal tibial osteotomy. An anatomical study. J Bone Joint Surg Am. 1992, 74: 1180-1185.PubMedGoogle Scholar
- Brazier J, Migaud H, Gougeon F, Cotten A, Fontaine C, Duquennoy A: Evaluation of methods for radiographic measurement of the tibial slope. A study of 83 healthy knees. Rev Chir Orthop Reparatrice Appar Mot. 1996, 82: 195-200.PubMedGoogle Scholar
- El-Azab H, Glabgly P, Paul J, Imhoff AB, Hinterwimmer S: Patellar height and posterior tibial slope after open- and closed-wedge high tibial osteotomy: a radiological study on 100 patients. Am J Sports Med. 2010, 38: 323-329. 10.1177/0363546509348050.View ArticlePubMedGoogle Scholar
- Genin P, Weill G, Julliard R: The tibial slope. Proposal for a measurement method. J Radiol. 1993, 74: 27-33.PubMedGoogle Scholar
- Insall J, Salvati E: Patella position in the normal knee joint. Radiology. 1971, 101: 101-104.View ArticlePubMedGoogle Scholar
- Hernigou P: Open wedge tibial osteotomy: combined coronal and sagittal correction. Knee. 2002, 9: 15-20. 10.1016/S0968-0160(01)00111-9.View ArticlePubMedGoogle Scholar
- Stoffel K, Willers C, Korshid O, Kuster M: Patellofemoral contact pressure following high tibial osteotomy: a cadaveric study. Knee Surg Sports Traumatol Arthrosc. 2007, 15: 1094-1100. 10.1007/s00167-007-0297-9.View ArticlePubMedGoogle Scholar
- Hohmann E, Bryant A, Imhoff AB: The effect of closed wedge high tibial osteotomy on tibial slope: a radiographic study. Knee Surg Sports Traumatol Arthrosc. 2006, 14: 454-459. 10.1007/s00167-005-0700-3.View ArticlePubMedGoogle Scholar
- Agneskirchner JD, Hurschler C, Stukenborg-Colsman C, Imhoff AB, Lobenhoffer P: Effect of high tibial flexion osteotomy on cartilage pressure and joint kinematics: a biomechanical study in human cadaveric knees. Winner of the AGA-DonJoy award 2004. Arch Orthop Trauma Surg. 2004, 124: 575-584. 10.1007/s00402-004-0728-8.View ArticlePubMedGoogle Scholar
- Giffin JR, Stabile KJ, Zantop T, Vogrin TM, Woo SL, Harner CD: Importance of tibial slope for stability of the posterior cruciate ligament deficient knee. Am J Sports Med. 2007, 35: 1443-1449. 10.1177/0363546507304665.View ArticlePubMedGoogle Scholar
- El-Azab H, Halawa A, Anetzberger H, Imhoff AB, Hinterwimmer S: The effect of closed- and open-wedge high tibial osteotomy on tibial slope: a retrospective radiological review of 120 cases. J Bone Joint Surg Br. 2008, 90: 1193-1197.View ArticlePubMedGoogle Scholar
- Insall J: Osteotomy. Surgery of the Knee. Edited by: Insall J, Windsor R, Scott W. 1993, New York: Churchill LivingstoneGoogle Scholar
- Staubli AE, Jacob HA: Evolution of open-wedge high-tibial osteotomy: experience with a special angular stable device for internal fixation without interposition material. Int Orthop. 2010, 34: 167-172. 10.1007/s00264-009-0902-2.PubMed CentralView ArticlePubMedGoogle Scholar
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