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  1. The first dorsal metacarpal artery flap, including dorsal digital nerves with or without dorsal branches of the proper digital nerves, can be used to reconstruct thumb pulp defects with good results. However, ...

    Authors: Shi-Ming Feng, Jia-Ju Zhao, Filippo Migliorini, Nicola Maffulli and Wei Xu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:685
  2. Reconstruction of reverse Hill-Sachs defect using osteo-chondral allograft has the advantages of spherical re-contouring and provision of smooth biological articular surface of the reconstructed humeral head. ...

    Authors: Amr Abdel-Mordy Kandeel
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:683
  3. Three-dimensional (3D) printing technology has developed rapidly in orthopaedic surgery and effectively achieves precise and personalized surgery. The purpose of this meta-analysis was to assess the efficacy o...

    Authors: Guang Shi, Wei Liu, Ying Shen and Xiyu Cai
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:682
  4. The objectives of this study were to build upon previously-reported 12-month findings by retrospectively comparing 24-month follow-up hospitalization charges and potentially-relevant readmissions in US lumbar ...

    Authors: Bradley Wetzell, Julie B. McLean, Kimberly Dorsch and Mark A. Moore
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:680
  5. Total hip arthroplasty (THA) with ceramic-on-ceramic (CoC) was created to minimise wear debris and aseptic loosening. A decade ago, a meta-analysis showed a 10-year survival rate of just 89%. Based on the exce...

    Authors: Ihab Ibraheam El-Desouky, Albaraa Hassan Helal and Ali Mohamed Reda Mansour
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:679
  6. Tears in the triangular fibrocartilage complex (TFCC) often manifest as ulnar wrist pain and limited wrist function. In chronic cases, the treatment of large tears with irreparable TFCC degeneration combined w...

    Authors: Kuang-Ting Yeh and Jui-Tien Shih
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:678
  7. Giving way and knee instability are common problems in patients with knee osteoarthritis, disrupting the daily activities and balance of the affected individual. The present study aimed to evaluate the postura...

    Authors: Liana Chaharmahali, Farzaneh Gandomi, Ali Yalfani and Alireza Fazaeli
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:677
  8. This finite element analysis assessed lateral compression (LC-1) fracture stability using machine learning for morphological mapping and classification of pelvic ring stability.

    Authors: Bin-Fei Zhang, Jun Wang, Yu-Min Zhang, Hui-Guang Cheng, Qian-Yue Cheng and Wen-Wen Cao
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:675
  9. The traditional strategy for fixing intra-articular distal humerus fractures is double plating placed in an orthogonal configuration, based on posterior approach. With a combined medial and lateral approach, a...

    Authors: Lingpeng Kong, Yan Wang, Qingsen Lu, Yong Han and Fu Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:674
  10. Steroid-induced osteonecrosis of the femoral head (ONFH) is a disease of the bone. Metabolism and genetic factors are generally considered to play an important role. The purpose of this study was to investigat...

    Authors: Tingting Liu, Yuju Cao, Changxu Han, Feimeng An, Tiantian Wang, Menghu Sun, Chao Ma, Qiumei Dong and Jianzhong Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:673
  11. Gabapentin and intravenous patient-controlled analgesia (PCA) can reduce postoperative pain scores, postoperative opioid use, and time to completing physical therapy compared to PCA alone after posterior spina...

    Authors: Ying Li, Jennylee Swallow, Christopher Robbins, Michelle S. Caird, Aleda Leis and Rebecca A. Hong
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:672
  12. This study explored the risk factors influencing the length of hospital stay (LOS) and establish whether the type of anesthesia is independently associated with the LOS in patients after primary unilateral tot...

    Authors: Xiaoqing Wang, He Li, Conghu Yuan and Hang Zhao
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:671
  13. The reliability of robotic arm-assisted total knee arthroplasty (RA-TKA) has been previously reported. In this study, we evaluated the predictive accuracy of the RA-TKA system in determining the required bone ...

    Authors: Xufeng Wan, Qiang Su, Duan Wang, Mingcheng Yuan, Yahao Lai, Hong Xu and Zongke Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:670
  14. Osteoporosis is one of the most common bone system diseases that is associated with an increased risk of bone fractures and causes many complications for patients. With age, the prevalence of this disease incr...

    Authors: Nader Salari, Niloofar Darvishi, Yalda Bartina, Mojdeh Larti, Aliakbar Kiaei, Mahvan Hemmati, Shamarina Shohaimi and Masoud Mohammadi
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:669
  15. It is challenging to determine the orthogonality of radiographs in daily clinical practice. The purpose of this study was to show the usefulness of an additional foot ring which might determine the orthogonali...

    Authors: Yanshi Liu, Kai Liu, Feiyu Cai, Tao Zhang and Aihemaitijiang Yusufu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:668
  16. Unicompartimental knee arthroplasty (UKA) is a promising and increasing application to treat unicompartimental knee osteoarthritis. However, revision arthroplasty numbers after UKA are unknown. Therefore, aim ...

    Authors: Nike Walter, Johannes Weber, Maximilian Kerschbaum, Edmund Lau, Steven M. Kurtz, Volker Alt and Markus Rupp
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:666
  17. Osteoporosis is a systemic disease characterized by impaired bone formation, increased bone resorption, and brittle bone fractures. The osteogenic differentiation of human bone marrow-derived mesenchymal stem ...

    Authors: Jun Li, Xingbiao Wu, Yaohua Shi and Hong Zhao
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:665
  18. Templating for total knee arthroplasty (TKA) is routinely performed on two-dimensional standard X-ray images and allows template-directed instrumentation. To date, there is no report on one-dimensional (1D) an...

    Authors: Michael Andreas Finsterwald, Salar Sobhi, Senthuren Isaac, Penelope Scott, Riaz J. K. Khan and Daniel P. Fick
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:664
  19. Osteoarthritis (OA) is a multifaceted condition that affects both the subchondral bones and the articular cartilage. Animal models are widely used as an effective supplement and simulation for human OA studies...

    Authors: Sharifah Zakiah Syed Sulaiman, Wei Miao Tan, Rozanaliza Radzi, Intan Nur Fatiha Shafie, Mokrish Ajat, Rozaihan Mansor, Suhaila Mohamed, Angela Min Hwei Ng and Seng Fong Lau
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:663
  20. To investigate the relationship between the infection rate and the timing of replacement of temporary external fixators with internal fixation, and the timing of immediate or delayed internal fixation after re...

    Authors: Zelin Ye, Shanwen Zhao, Canjun Zeng, Ziheng Luo, Song Yuan and Runguang Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:662
  21. Failure of fixation (FF) in pubic symphysis diastasis (SD) ranges between 12 and 75%, though whether it influences functional outcomes is still debated. The objective of this study is to evaluate the impact of...

    Authors: Claudio Rojas, Ernesto Ewertz and Jose Miguel Hormazábal
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:661
  22. Osteoporosis (OP) is a well-known chronic degenerative disease, with impaired mesenchymal stem cells (MSCs) function and suppressed osteogenic differentiation. Total glycosides from Eucommia ulmoides seed (TGE...

    Authors: Yu-hu Zhou and Qiang Xie
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:660
  23. Spinal metastases are indicative of progressive cancer which can lead to vertebral body fractures and spinal cord compression. Radiofrequency ablation (RFA) treatment is infrequently used in patients with refr...

    Authors: Navanith Murali, Thomas Turmezei, Sumbal Bhatti, Puja Patel, Thomas Marshall and Toby Smith
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:659
  24. Chondrogenic differentiation of human adipose-derived stem cells (hADSCs) is important for cartilage generation and degradation. LncRNAs play an essential role in stem cell differentiation. However, the role a...

    Authors: Qinqin Yang, Jiajia Guo, Zhijing Ren, Bo Li, Haifeng Huang and Zhen Yang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:658
  25. Cartilage defect has a limited capacity to heal. In this context, we hypothesized that hyaluronic acid (HA) hydrogel encapsulated BMP-14-modified adipose-derived mesenchymal stem cells (ADSCs) could accelerate...

    Authors: Hao Liu, Yongjun Rui, Jun Liu, Fandong Gao and Yesheng Jin
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:657
  26. Socket fixation with bone grafting for dysplastic hips is technically demanding, and inadequate coverage of the socket may cause poor results in patients with severely dysplastic hips. An accurate technique to...

    Authors: Yuki Okutani, Hiroshi Fujita, Hideto Harada, Masanao Kataoka, Yu Shimizu and Yoshiki Murotani
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:655
  27. Perioperative hypoalbuminemia of the posterior lumbar interbody fusion (PLIF) can increase the risk of infection of the incision site, and it is challenging to accurately predict perioperative hypoproteinemia....

    Authors: Bo Liu, Junpeng Pan, Hui Zong and Zhijie Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:654
  28. The outcomes of nonagenarian patients undergoing orthopaedic surgery are not well understood. We investigated the 30-day mortality after surgical treatment of unilateral hip fracture. The relationship between ...

    Authors: Laurence Weinberg, Bobby Ou Yang, Luka Cosic, Sarah Klink, Peter Le, Jasun Kai Li, Anoop Ninan Koshy, Daryl Jones, Rinaldo Bellomo, Chong Oon Tan and Dong-Kyu Lee
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:653
  29. Bone morphogenetic protein 9 (BMP9) has been identified as a crucial inducer of osteoblastic differentiation in mesenchymal stem cells (MSCs). Although microRNAs (miRNAs) are known to play a role in MSC osteog...

    Authors: Yunyuan Zhang, Xuran Jing, Zhongzhu Li, Qingwu Tian, Qing Wang and Xian Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:652
  30. Five different sacral fracture fixation methods were compared using finite element (FE) analysis to study their biomechanical characteristics.

    Authors: Jianxiong Zheng, Xiaoreng Feng, Jie Xiang, Fei Liu, Frankie K. L. Leung and Bin Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:651
  31. Low-magnitude high-frequency vibration (LMHFV) has been reported to be capable of promoting osteoblast proliferation and differentiation. Reduced osteoblast activity and impaired bone formation were related to...

    Authors: Zhaoyu Fu, Xu Huang, Pengcheng Zhou, Bo Wu, Long Cheng, Xinyu Wang and Dong Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:650
  32. This study aimed to describe the characteristics of plasma D-dimer level with increasing age and establish a new age-adjusted D-dimer cutoff value for excluding preoperative lower limb deep vein thrombosis (DV...

    Authors: Kexin Zhang, Yanbin Zhu, Yunxu Tian, Miao Tian, Xiuting Li and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:649
  33. Changes in sex hormones are thought to play an important role in bone health in postmenopausal women. Our aim in this study was to evaluate the association between levels of estradiol (E2), which is the most p...

    Authors: Zhongxin Zhu, Jin Zhao, Yanfei Fang and Rongwei Hua
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:648
  34. Rheumatoid arthritis (RA) is a chronic autoimmune disease, which commonly affects women. Accumulating evidence shows that differentially expressed circular RNAs (circRNAs) play crucial roles in the progress of...

    Authors: Yufeng Chen, Xianghe Xu, Xuegang Li, Junlong Zhong, Biao Wu, Jie Shang, Ning Jiang, Bin Wang, Shuping Zhong and Huading Lu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:647
  35. Osteoarthritis is a chronic inflammatory disease of the joints associated with significant morbidity and lower quality of life. Current treatment strategies focus on reducing cartilage degeneration but fail to...

    Authors: Jiyou Li, Ning Liu, Zhipeng Huang, Wantao Wang, Donghua Hou and Wenbo Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:646
  36. Osteosarcoma (OS) is the most common aggressive bone tumor in children and teenagers. Doxorubicin (DOX) is a chemotherapeutic drug for OS. This study aims to reveal the effects and underneath mechanism of DOX ...

    Authors: Abulimiti Amuti, Dehu Liu, Ayiguli Maimaiti, Yao Yu, Yalikun Yasen, Haoguang Ma, Rui Li, Shurong Deng, Fei Pang and Youliang Tian
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:645
  37. Osteoporotic vertebral compression fracture (OVCF) is one of the most common fragile fractures, and percutaneous vertebroplasty provides considerable long-term benefits. At the same time, there are many report...

    Authors: Wei Mao, Fei Dong, Guowei Huang, Peiliang He, Huan Chen, Shengnan Qin and Aiguo Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:644
  38. Enhanced recovery after surgery (ERAS) program advocates implementation of perioperative goal-directed fluid therapy and reduced application of colloidal fluids. It should be used reasonably selectively in hig...

    Authors: Shaoyun Zhang, Haibo Si, Jinwei Xie, Yuangang Wu, Qinsheng Hu, Yi Zeng, Fuxing Pei and Bin Shen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:643
  39. Screws are the most frequently inserted orthopaedic implants. Biomechanical, laboratory-based studies are used to provide a controlled environment to investigate revolutionary and evolutionary improvements in ...

    Authors: James W. A. Fletcher, Verena Neumann, Lisa Wenzel, Boyko Gueorguiev, R. Geoff Richards, Harinderjit S. Gill, Michael R. Whitehouse and Ezio Preatoni
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:642
  40. To achieve the proper sagittal alignment, previous studies have developed different assessment systems for adult degenerative scoliosis (ADS) which could help the spine surgeon in making treatment strategies. ...

    Authors: Xiangyao Sun, Wenzhi Sun, Siyuan Sun, Hailiang Hu, Sitao Zhang, Chao Kong and Shibao Lu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:641
  41. Total hip arthroplasty (THA) instability is influenced by acetabular component positioning, spinopelvic function and sagittal spinal alignment. Obesity is considered as a risk factor of THA instability, but th...

    Authors: Henryk Haffer, Zhen Wang, Zhouyang Hu, Luis Becker, Maximilian Müllner, Christian Hipfl, Matthias Pumberger and Yannick Palmowski
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:640
  42. Autologous bone has been used for posterior lumbar intervertebral fusion (PLIF). However, harvesting autologous bone graft is associated with donor site complications. We previously developed a hydroxyapatite/...

    Authors: Toshitaka Yoshii, Motonori Hashimoto, Satoru Egawa, Takashi Hirai, Hiroyuki Inose and Atsushi Okawa
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:639
  43. There are discrepancies in the understanding of the structure of the capsuloligamentous complex of the first metatarsophalangeal joint (MTPJ); this study aims to investigate the differences with previous anato...

    Authors: Jin-e Wang, Rong-jie Bai, Hui-li Zhan, Wen-ting Li, Zhan-hua Qian, Nai-li Wang and Yuming Yin
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:638
  44. This study was to explore the effect of exosomal miR-155 derived from bone marrow mesenchymal stem cells (BMSCs) on stemness maintenance and drug resistance in MPC-11 multiple myeloma cells.

    Authors: Xinyu Gao, Jin Zhou, Jinghua Wang, Xiushuai Dong, Yuying Chang and Yinglan Jin
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:637
  45. Adhesive skin materials have increasingly been used in orthopedic surgery. We aimed to compare the efficacy and safety of skin adhesive (2-octyl cyanoacrylate and polymer mesh, Dermabond Prineo) and interrupte...

    Authors: Gun-Woo Lee, Woo Kyoung Kwak and Keun-Bae Lee
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:636
  46. Although the high offset Tri-Lock bone preservation stem (BPS) was used widely, few studies explored the clinical and radiological results. The purpose of this study was to determine the clinical and radiologi...

    Authors: Linbo Peng, Jun Ma, Yi Zeng, Yuangang Wu, Haibo Si and Bin Shen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:635
  47. Our study aimed to explore the clinical therapeutic effects of ultrasound-guided five-point injection of botulinum toxin type A for patients with trapezius hypertrophy.

    Authors: Wanying Chen, Xiaoyu Zhang, Yingying Xu, Zemin Xu, Haiyan Qin and Lianbo Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:634

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