Table 1 Correlation between expression of RUNX2-circRNAs and clinicopathological characteristics of OS patients
Clinical variables (N) | circ_0076684 (low/high) | P | circ_0003563 (low/high) | P | circ_0076691 (low/high) | P |
|---|---|---|---|---|---|---|
Age | ||||||
< 25y (24) | 10/14 |  | 13/11 |  | 11/13 |  |
≥ 25y (17) | 11/6 | 0.128 | 8/9 | 0.448 | 10/7 | 0.308 |
Gender | ||||||
Male (22) | 13/9 | Â | 8/13 | Â | 11/11 | Â |
Female (19) | 8/11 | 0.220 | 12/7 | 0.134 | 10/9 | 0.558 |
Tumor size | ||||||
< 5 cm (25) | 17/8 |  | 13/12 |  | 15/10 |  |
≥ 5 cm (16) | 4/12 | 0.008 | 8/8 | 0.577 | 6/10 | 0.139 |
Lung metastasis | ||||||
No (26) | 17/9 | Â | 15/11 | Â | 15/11 | Â |
Yes (15) | 4/11 | 0.019 | 6/9 | 0.222 | 6/9 | 0.222 |
Enneking stage | ||||||
I + IIA (25) | 17/8 |  | 15/10 |  | 14/11 |  |
IB + III (16) | 4/12 | 0.008 | 6/10 | 0.139 | 7/9 | 0.328 |
Location | ||||||
Femur/tibia (28) | 13/15 | Â | 15/13 | Â | 15/13 | Â |
Elsewhere (13) | 8/5 | 0.287 | 6/7 | 0.457 | 6/7 | 0.457 |
Differentiation | ||||||
Well/moderately (27) | 14/13 | Â | 13/14 | Â | 16/11 | Â |
Poorly/undifferentiated (14) | 7/7 | 0.585 | 8/6 | 0.415 | 5/9 | 0.136 |