Fig. 3

Circ_0076684 promoted OS progression in vitro and in vivo. A–C Regulation of circ_0076684, circ_0003563 and circ_0076691 on OS cell proliferation evaluated by CCK8 assays. D, E Regulation of circ_0076684 on OS cells proliferation evaluated by EdU assays. F–I Regulation of circ_0076684 on OS cell migration and invasion evaluated using wound-healing and Transwell assays, respectively. (J,K) Regulation of circ_0076684 on OS tumor growth in vivo evaluated by xenograft tumor model assays. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001