Fig. 5

GPS inhibits chondrocyte extracellular matrix degradation and ameliorates chondrocyte hypertrophy. A–C The mRNA expression levels of col2, col10 and aggrecan in chondrocytes were examined by q-PCR. D Western blot analysis of the protein levels of col2, col10 and aggrecan in chondrocytes. E–G Relative expression levels of col2, col10 and aggrecan were analyzed semiquantitatively. H Immunofluorescence staining of col2. *P < 0.01, ***P < 0.001