Fig. 4

Effect of GPS on the LPS-induced expression of extracellular matrix-degrading proteases in chondrocytes. A–B The mRNA expression levels of MMP-13 and ADAMTS5 in chondrocytes were examined by q-PCR. C Western blot analysis of the protein expression of MMP-13 and ADAMTS5. D–E The relative expression levels of MMP-13 and ADAMTS5 were analyzed semiquantitatively. *P < 0.05, **P < 0.01, ***P < 0.001