Fig. 3

Inhibitory effect of GPS on LPS-induced chondrocyte inflammation. A–B Chondrocytes were treated with LPS (5 μg/ml) for 24 h and GPS (10, 20 and 40 μM) for another 24 h. IL-1β and PGE2 expression in culture supernatants was examined by ELISA. C–D q-PCR was used to determine IL-1β and COX2 mRNA expression levels in chondrocytes. *P < 0.05, ***P < 0.001