Fig. 2

Effects of GPS on cell viability. A GPS (0, 10, 20, 40, 80 and 160 μM) was incubated with chondrocytes for 24 h. Cell viability was determined by a CCK-8 assay. B Chondrocytes were pretreated with 5 μg/ml LPS for 24 h and then treated with different concentrations of GPS (10, 20 and 40 μM) for 24, 48 and 72 h, and cell viability was determined by a CCK-8 assay. C Proportion of chondrocytes in the proliferative phase relative to the total cell number. D Chondrocytes were pretreated with 5 μg/ml LPS for 24 h and then treated with different concentrations of GPS (10, 20 and 40 μM) for 24 h. Proliferative chondrocytes were labeled with EdU; green cells indicate proliferating chondrocytes, and nuclei are depicted in blue. *P < 0.05, ***P < 0.001