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Fig. 8 | Journal of Orthopaedic Surgery and Research

Fig. 8

From: Geniposide alleviates cholesterol-induced endoplasmic reticulum stress and apoptosis in osteoblasts by mediating the GLP-1R/ABCA1 pathway

Fig. 8

GEN inhibited CHO-induced ER stress in osteoblasts by activating GLP-1R expression. The protein expressions of GRP78 (A,B), p-PERK (A,C), PREK (A,D), p-IRE1α (A,E), IRE1α (A,F), ATF6(A,G), and CHOP(A,H) were analyzed by Western blot. * p < 0.05; ** p < 0.01; ns, no statistical difference. GEN (25 µM), CHO + GEN (25 µM); EX9-39, CHO + GEN (25 µM) + Exendin9-39 (200nM)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X