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Fig. 7 | Journal of Orthopaedic Surgery and Research

Fig. 7

From: Geniposide alleviates cholesterol-induced endoplasmic reticulum stress and apoptosis in osteoblasts by mediating the GLP-1R/ABCA1 pathway

Fig. 7

GEN inhibited CHO-induced apoptosis in osteoblasts by activating GLP-1R expression. The protein expressions of GLP-1R(A,B), Bcl2 (A,C), Bax (A,D), caspase3 (A,E), and cleaved caspase3 (A,F) were analyzed by Western blot. (G,H) Apoptosis analysis was applied by flow cytometry. * p < 0.05; ** p < 0.01; ns, no statistical difference. GEN (25 µM), CHO + GEN (25 µM); EX9-39, CHO + GEN (25 µM) + Exendin9-39 (200nM)

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