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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Geniposide alleviates cholesterol-induced endoplasmic reticulum stress and apoptosis in osteoblasts by mediating the GLP-1R/ABCA1 pathway

Fig. 6

GEN inhibited CHO-induced apoptosis in osteoblasts by activating ABCA1 expression. The protein expressions of ABCA1 (A,B), Bcl2 (A,C), Bax (A,D), caspase3 (A,E), and cleaved caspase3 (A,F) were analyzed by Western blot. (G,H) Apoptosis analysis was performed by flow cytometry. * p < 0.05; ** p < 0.01; ns, no statistical difference. GEN (25 µM), CHO + GEN (25 µM); DIDS, CHO + GEN (25 µM) + DIDS (20µM)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X