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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats

Fig. 2

p75NTR promotes apoptosis in Rat BMSCs. (A) Expression of p75NTR and sortilin was detected by RT-qPCR and WB. (B) Cell viability assessment by CCK-8. (C) FCM analysis of cell apoptosis. (D) Detection of apoptosis-related proteins Caspase-3, BCL-2, and BAX expression by WB. (E) CO-IP analysis of protein-protein interaction between p75NTR and sortilin. *P < 0.05 vs. si-NC. #P < 0.05 vs. oe-NC

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X