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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Exosomes derived from umbilical cord-mesenchymal stem cells inhibit the NF-κB/MAPK signaling pathway and reduce the inflammatory response to promote recovery from spinal cord injury

Fig. 4

UC-MSC-derived exosomes inhibited the apoptosis of BV2 microglia. (A) Effects of exosomes on the apoptosis of BV2 microglia by Western blot. (B) Bax, (C) Caspase 9, (D) Caspase 3, and (E) Bcl-2 relative level to β-actin in BV2 microglia. Levels of apoptotic factors (F) Bax, (G) Caspase 3, and (H) Caspase 9 by immunofluorescence. Scale bar = 50 μm. *p < 0.05, **p < 0.01, ***p < 0.001

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