Table 4 GRADE evidence profile for outcomes
Outcomes | Relative effect (95% CI) | No of Participants (Studies) | Quality of the evidence (GRADE) |
|---|---|---|---|
Total opioid consumption | -0.50 (-0.70, -0.31) | 400 (4) | ⊕⊕⊕⊕high |
Pain score during rest at 1 week | -0.49 (-0.80, -0.18) | 315 (4) | ⊕⊕⊕moderate2 |
Pain score during rest at 2–3 week | -0.54 (-1.02, -0.07) | 363 (4) | ⊕⊕low1, 2 |
Pain score during activity at 1 week | -0.64 (-0.94, -0.34) | 315 (4) | ⊕⊕⊕moderate2 |
Pain score during activity at 2–3 week | -0.62 (-1.04, -0.19) | 469 (5) | ⊕⊕⊕moderate1 |
The rate of postoperative dizziness | 0.99 (0.57, 1.75) | 429 (6) | ⊕⊕⊕⊕high |
The rate of postoperative drowsiness | 1.83 (1.08, 3.09) | 310 (4) | ⊕⊕low1,2 |
The rate of postoperative insomnia | 0.99 (0.74, 1.32) | 215 (3) | ⊕⊕⊕moderate2 |
The rate of postoperative nausea and vomiting | 0.69 (0.50, 0.95) | 692 (8) | ⊕⊕⊕⊕high |
The rate of postoperative constipation | 0.90 (0.66, 1.23) | 382 (5) | ⊕⊕⊕moderate2 |
The rate of postoperative appetite loss | 0.91 (0.77, 1.07) | 87 (2) | ⊕⊕⊕moderate2 |
The rate of postoperative fatigue | 0.92 (0.79, 1.08) | 378 (5) | ⊕⊕⊕moderate2 |
The rate of postoperative dry mouth | 0.97 (0.71, 1.34) | 382 (5) | ⊕⊕⊕moderate2 |