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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway

Fig. 5

Effects of CCR10-siRNA or 740Y-P on PI3K/Akt/mTOR pathway. The CHON-001 cells were divided into three groups: IL-1β + control-siRNA, IL-1β + CCR10-siRNA, and IL-1β + CCR10-siRNA + 740Y-P group. (A) p-PI3K, p-Akt, and p-mTOR levels were determined using Western blotting. (B-D) Quantification of the p-PI3K/PI3K, p-Akt/Akt, and p-mTOR/mTOR ratios. * P < 0.05, **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X