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Table 2 Top differentially expressed genes in bone and tissue

From: Aseptic loosening around total joint replacement in humans is regulated by miR-1246 and miR-6089 via the Wnt signalling pathway

Location

Gene

logFC

AveExpr

t

P Value

adj.P.Val

B

Bone

DEFA1B

 − 9.87323

10.52257

 − 5.89125

6.82E-06

0.00011

3.695094

DEFA1

 − 9.92204

10.51236

 − 5.88224

6.96E-06

0.000111

3.676803

LTF

 − 8.9081

8.370686

 − 5.57556

1.42E-05

0.000161

3.187831

COMP

8.113538

1.880959

5.378271

2.27E-05

0.000213

2.709947

DEFA3

 − 9.98611

8.880224

 − 5.01815

5.34E-05

0.000376

1.835942

Tissue

LINC02154

5.085439

−2.17528

5.23428

8.12E-06

0.000152

2.337842

APOC2

5.065549

0.516944

4.13716

0.000213

0.001447

0.577554

CHIT1

8.470192

3.545606

4.022007

0.000297

0.001844

0.334267

HP

 − 5.8447

1.932185

-3.85548

0.000479

0.00265

 − 0.08945

DNASE2B

5.064432

 − 0.82393

3.731657

0.000681

0.00347

 − 0.55021