Fig. 3

Knockdown of LINC00958 reduced LINC00958 expression and increased miR-214-3p expression. CHON-001 cells were stimulated with 10 ng/ml IL-1β, and transfected with control-siRNA, the miR-214-3p inhibitor, the inhibitor control or LINC00958-siRNA. A–E The levels of LINC00958 and miR-214-3p were measured using qRT-PCR. **P < 0.01 versus siRNA-NC group; ^##P < 0.01 versus Inhibitor NC group; ^&&P < 0.01 versus siRNA-LINC00958 + inhibitor NC group. ^■■P < 0.01 versus Control group; ^▲▲P < 0.01 versus IL-1β + siRNA-NC group; ^★P < 0.05, ^★★P < 0.01 versus IL-1β + siRNA-LINC00958 + inhibitor NC group