Table 6 Two groups of serum metabolites mainly involved in the metabolic pathway analysis results
Hits | Raw P | LOG10(P) | Holm adjust | FDR | Impact | |
|---|---|---|---|---|---|---|
Ammonia acyl tRNA biosynthesis | 15 | 5.15E−14 | 13.288 | 4.33E−12 | 4.33E−12 | 0 |
Valine, leucine, and isoleucine biosynthesis | 4 | 2.48E−05 | 4.6061 | 0.002031 | 0.000694 | 0 |
Alanine, glutamic acid, and aspartic acid metabolism | 6 | 4.98E−05 | 4.3026 | 0.004035 | 0.001046 | 0.53446 |
Glycine, serine, and threonine metabolism | 5 | 0.001237 | 2.9078 | 0.096458 | 0.01484 | 0.38904 |
Phenylalanine, tyrosine, and tryptophan biosynthesis | 2 | 0.003772 | 2.4234 | 0.29044 | 0.035239 | 1 |
Glycolysis/sugar dysplasia | 4 | 0.003776 | 2.423 | 0.29044 | 0.035239 | 0.03011 |
Synthesis and degradation of ketone body | 2 | 0.006184 | 2.2087 | 0.46381 | 0.051947 | 0.6 |
D-glutamine with D-glutamine metabolism | 2 | 0.009125 | 2.0398 | 0.66613 | 0.058962 | 0.5 |
Metabolism of phenylalanine | 2 | 0.025642 | 1.591 | 1 | 0.13462 | 0.35714 |
Citric acid cycle (TCA cycle) | 2 | 0.092117 | 1.0357 | 1 | 0.40725 | 0.12311 |
Glutathione metabolism | 2 | 0.16139 | 0.79212 | 1 | 0.61621 | 0.10839 |
Triglyceride metabolism | 1 | 0.34321 | 0.46444 | 1 | 0.87362 | 0.23676 |