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Table 5 Names and changes in serum metabolites in the two study groups

From: Analysis of the relationship of refractory gout between potential biomarkers and diet structure and lifestyle based on 1H-NMR

Chemical shift value

Metabolite

VIP

Variation trend

0.82

HDL

1.1048

0.98, 2.26

Valine

1.046

3.25

Arginine

1.25

3.35

Proline

1.01

0.86

VLDL/LDL

1.073

1.33

Lactic acid

0.53506

1.38

Prostaglandin D2

1.29

2.06

N-acetyl glycoprotein

1.16

2.14

O-acetyl glycoprotein

1.17

2.15

Homocysteine

1.27

2.25

Prostaglandin E2

1.08

2.31

3-Hydroxybutyric acid

1.35

2.39

Malic acid

1.27

2.4

Succinic acid

1.08

3.12

Phosphocreatine

1.1

3.22

Glycerol phosphocholine

1.16

3.28, 3.26

Betaine

1.02

3.42

Taurine

1.07

3.57

Glycine

1.45

3.58

Threonine

1.51

3.63

Inositol

1.22

3.64

Glycerine

1.29

3.66

Glycerol

1.19

3.87

Methionine

1.05

3.89

Aspartic acid

1.21

3.94

Creatine

1.41

3.98

Phenylalanine

1.27

0.93, 1.97, 3.65

Isoleucine

1.39

1.48, 3.79

Alanine

1.488

1.71, 0.94, 3.72

Leucine

1.34

1.72, 3.01

Lysine

1.16

1.91, 1.92

Acetate

1.21

2.06, 2.35

Glutamate

1.31

2.1, 2.41

Glutamine

1.06

2.16, 2.17

Butyric acid

1.36

2.22, 2.28

Acetoacetic acid

1.04

2.24, 2.38

Acetone

1.28

2.52, 2.55

Citric acid

1.05

3.62, 4.65

D- glucose

1.36

6.87, 7.22

Tyrosine

1.1