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Table 3 Micro-CT analysis of mice cortical bone (n = 6). Iron accumulation in KO mice significantly affected cortical bone related parameters

From: Iron accumulation induced by hepcidin1 knockout accelerates the progression of aging osteoporosis

 

WT

KO

Cortical bone thickness (mm)

0.14 ± 0.006*

0.11 ± 0.003*

Cortical area (mm2)

0.73 ± 0.057*

0.66 ± 0.066*

Endosteal surface perimeter

3.78 ± 0.16*

3.91 ± 0.13

Periosteum perimeter

5.25 ± 0.76

5.47 ± 0.66*

  1. The asterisks (*) indicate significant differences at P < 0.05