Fig. 7

Circ_0006640 is packaged into exosomes. A TEM images of exosomes. B Determination of exosomal size distribution by NTA. C Detection of exosomal markers CD9 and CD81 by western blotting. D BV2 cells were incubated with PBS or MSC-exosomes (BMSC-exo), and levels of circ_0006640 were detected by qRT-PCR analysis. E BMSCs were transfected with si-circ_0006640 or oe-circ_0006640, and levels of circ_0006640 were tested by qRT-PCR. F Detection of circ_0006640 level in exosomes isolated from BMSCs transfected with si-circ_0006640 or oe-circ_0006640. G BV2 cells were incubated with the exosomes isolated form si-circ_0006640- or oe-circ_0006640-transfected BMSCs, and levels of circ_0006640 were tested by qRT-PCR. *P < 0.05