Fig. 4

The NOD-like receptor signaling pathway is associated with high expression levels of hsa_piR_019949 in C28/I2 cells. A The heatmap displays the contrasting levels of piRNAs that are expressed in C28/I2 cells transfected with hsa_piR_019949 mimics in comparison to the normal control. B The volcano map illustrates the differential expression of piRNAs in C28/I2 cells transfected with hsa_piR_019949 mimics compared to the normal control. C The GO enrichment analysis highlights the enrichment of differentially expressed mRNA in terms of Gene Ontology categories. D The KEGG enrichment analysis reveals the enrichment of differentially expressed mRNA in relation to the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways