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Table 2 Main outcomes of the studies included in the systematic review

From: Risk of low bone mineral density in patients with haemophilia: a systematic review and meta-analysis

Study

Low BMD

(H)

Low BMD rate (H)

Low BMD

(C)

Low BMD rate (C)

LS BMD

(H) (kg/m2)

LS BMD

(C) (kg/m2)

FN BMD

(H) (kg/m2)

FN BMD

(C) (kg/m2)

TH BMD

(H) (kg/m2)

TH BMD

(C) (kg/m2)

Barnes, C

N/A

N/A

N/A

N/A

0.72 ± 0.19

0.79 ± 0.19

N/A

N/A

N/A

N/A

Abdelrazik, N

N/A

N/A

N/A

N/A

0.48 ± 0.13

0.55 ± 0.14

N/A

N/A

N/A

N/A

Nair, A. P

N/A

N/A

N/A

N/A

0.82 ± 0.14

0.93 ± 0.11

N/A

N/A

0.73 ± 0.15

0.94 ± 0.11

Mansouritorghabeh, H

N/A

N/A

N/A

N/A

1.13 ± 0.11

1.29 ± 0.23

0.802 ± 0.23

1.45 ± 0.50

N/A

N/A

Tlacuilo-Parra, A

24/62

38.71%

10/62

16.13%

0.568 ± 0.13

0.632 ± 0.16

N/A

N/A

N/A

N/A

Mansouritorghabeh, H

5/14

35.71%

0/14

0%

1.09 ± 0.24

1.21 ± 0.15

0.99 ± 0.21

1.17 ± 0.30

N/A

N/A

Christoforidis, A

2/26

7.69%

0/13

0%

N/A

N/A

N/A

N/A

N/A

N/A

Rezaeifarid, M

N/A

N/A

N/A

N/A

0.908 ± 0.13

0.987 ± 0.19

0.889 ± 0.18

0.969 ± 0.11

N/A

N/A

Alioglu, B

N/A

N/A

N/A

N/A

0.52 ± 0.14

0.98 ± 0.23

N/A

N/A

N/A

N/A

Anagnostis, P

28/104

26.92%

10/50

20%

1.047 ± 0.17

1.065 ± 0.16

0.938 ± 0.16

1.015 ± 0.18

0.929 ± 0.16

1.018 ± 0.19

Wells, A. J

11/37

29.73%

6/37

16.22%

0.985 ± 0.20

1.082 ± 0.18

0.792 ± 0.22

0.905 ± 0.23

0.900 ± 0.20

1.051 ± 0.18

Eldash, H. H

5/30

16.67%

0/37

0%

0.63 ± 0.12

0.67 ± 0.11

N/A

N/A

N/A

N/A

Sossa Melo, C. L

28/89

31.46%

7/90

7.78%

N/A

1.06

(IQR:0.84–1.23)

N/A

N/A

N/A

N/A

Ashritha, A

8/38

21.05%

0/38

0%

0.487

(IQR:0.43–0.56)

0.549

(IQR:0.46–0.60)

N/A

N/A

N/A

N/A

Ekinci, O

10/41

24.39%

0/40

0%

0.92

(Min:0.83, Max:1.22)

1.01

(Min:0.01, Max:1.21)

0.92

(Min:0.71, Max:1.19)

1.12

(Min:0.94, Max:2.09)

0.94

(Min:0.70, Max:1.21)

1.12

(Min:0.94, Max:2.09)

El-Mikkawy, D. M. E

14/40

35%

0/10

0%

N/A

N/A

N/A

N/A

N/A

N/A

Ehsanbakhsh, A

18/57

31.58%

8/60

13.33%

− 1.1 ± 50.07

− 0.1 ± 78.20

N/A

N/A

− 0.0 ± 63.94

− 0.0 ± 33.98

Mohamed, H. R

11/39

28.21%

0/20

0%

0.61 ± 0.18

0.98 ± 0.10

N/A

N/A

N/A

N/A

Patel, G. R

16/39

15.38%

6/40

15%

0.56

(Min:0.19, Max:1.11)

0.67

(Min:0.21, Max:1.15)

N/A

N/A

0.49

(Min:0.27, Max:0.97)

0.64

(Min:0.31, Max:1.06)

  1. BMD Bone mineral density, H Haemophilia, C Controls, LS Lumbar spine, FN Femoral neck, TH Total hip, N/A Non-available
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