Table 1 Main characteristics of the studies included in the systematic review
From: Risk of low bone mineral density in patients with haemophilia: a systematic review and meta-analysis
Study | Year | Country | NO (H) | NO (C) | H type (A/B) | Mean age (H) (years) | Mean age (C) (years) | BMI (H)(kg/m2) | BMI (C)(kg/m2) | Infected (HBV/HCV/HIV) |
|---|---|---|---|---|---|---|---|---|---|---|
Barnes, C | 2004 | Australia | 19 | 215 | 19/0 | 12.2 ± 3.5 | 12.8 ± 2.1 | N/A | N/A | NA/8/NA |
Abdelrazik, N | 2007 | Egypt | 30 | 30 | 21/9 | 4.97 ± 3.64 | 5.09 ± 3.64 | 16.76 ± 2.08 | 17.33 ± 2.19 | 0/0/0 |
Nair, A. P | 2007 | India | 50 | 50 | 42/8 | 29.53 ± 9.27 | 29.20 ± 3.79 | 19.16 ± 3.8 | 23.62 ± 2.79 | 2/18/1 |
Mansouritorghabeh, H | 2008 | Iran | 18 | 18 | 18/0 | 29.05 ± 8.62 | 29.05 ± 8.61 | 22.43 ± 3.30 | 23.64 ± 3.65 | 1/11/NA |
Tlacuilo-Parra, A | 2008 | Mexico | 62 | 62 | 62/0 | 9.02 ± 3.70 | 9.30 ± 3.70 | 18.40 ± 4.50 | 20.20 ± 5.70 | N/A |
Mansouritorghabeh, H | 2009 | Iran | 14 | 14 | 0/14 | 30.57 ± 12.18 | 30.50 ± 12.14 | 25.37 ± 5.23 | 25.15 ± 4.89 | NA/11/NA |
Christoforidis, A | 2010 | Greece | 26 | 13 | 26/0 | 12.08 ± 4.44 | 11.45 ± 5.26 | N/A | N/A | NA/0/0 |
Rezaeifarid, M | 2011 | Iran | 55 | 87 | N/A | 23.5 (Min:16, Max:35) | 25.1 (Min:15, Max:35) | N/A | N/A | N/A |
Alioglu, B | 2012 | Turkey | 44 | 40 | 44/0 | 160months (Min:36, Max:216) | 146months (Min:42, Max:240) | N/A | N/A | N/A |
Anagnostis, P | 2012 | Greece | 104 | 50 | 90/14 | 45.87 ± 15.15 | 44.90 ± 12.80 | 27.05 ± 4.51 | 28.49 ± 4.39 | 4/42/7 |
Wells, A. J | 2015 | UK | 37 | 37 | 37/0 | 31 (IQR:13–49) | 35 (IQR:23–47) | 25.4 (IQR:19.7–31.1) | 26 (IQR:22.6–30.0) | NA/23/12 |
Eldash, H. H | 2017 | Egypt | 37 | 37 | N/A | 8.3 ± 3.5 | 7.3 ± 2.2 | N/A | N/A | 0/0/0 |
Sossa Melo, C. L | 2018 | Colombia | 90 | 90 | 79/11 | N/A | N/A | N/A | N/A | N/A |
Ashritha, A | 2019 | India | 38 | 38 | 35/3 | 8.7 ± 3.6 | 8.7 ± 3.5 | 13.8 (IQR:12.9–15.2) | 14.5 (IQR:13.6–15.5) | N/A |
Ekinci, O | 2019 | Turkey | 41 | 40 | 41/0 | 26 (Min:18, Max:56) | 30 (Min:18, Max:54) | 22.7 (Min:15, Max:30) | 24.2 (Min:17, Max:32) | 3/0/0 |
El-Mikkawy, D. M. E | 2019 | Egypt | 40 | 10 | 40/0 | 10.98 ± 3.85 | 10.80 ± 3.49 | 18.64 ± 3.53 | Matched | N/A |
Ehsanbakhsh, A | 2020 | Iran | 57 | 60 | 57/0 | 32.9 ± 77.32 | 34.8 ± 87.40 | 21.3 ± 49.89 | 22.4 ± 68.78 | N/A |
Mohamed, H. R | 2020 | Egypt | 39 | 20 | 35/4 | 9.23 ± 4.36 | 9.40 ± 4.02 | 11.79 ± 3.90 | 12.30 ± 4.13 | 0/5/0 |
Patel, G. R | 2022 | India | 39 | 40 | 35/4 | 9.0 (Min:1, Max:17) | 9.5 (Min:1, Max:17) | 13.8 (Min:10.6, Max:27.7) | 14.5 (Min:11.4, Max:23.2) | 0/0/0 |