Fig. 2

Circ_HECW2 was highly expressed in LPS-induced osteoblasts. Human osteoblasts HFOB1.19 were treated with 10 µg/mL LPS for 24 h, with cells free of LPS treatment as the control. A RT-qPCR detected Circ_HECW2 expression in cells. B TUNEL detected cell apoptosis. C Western blot detected the apoptosis related protein cleaved-caspase-3. The cell experiments were independently repeated 3 times. Data were expressed as mean ± standard deviation and analyzed using t test, *P < 0.05