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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Overexpression of lncRNA LINC00665 inhibits the proliferation and chondroblast differentiation of bone marrow mesenchymal stem cells by targeting miR-214-3p

Fig. 2

Chondrogenic differentiation and activity regulation of BMSCs. A. LINC00665 level in BMSCs chondrogenic differentiation within 14 days. B. The change in cartilage matrix proteoglycan GAG level within 14 days of BMSCs chondrogenic differentiation was detected by Alcian blue staining. (** P < 0.01, *** P < 0.001, compared with no differentiation group) C. Transfection efficiency of LINC00665 overexpression in BMSCs. D. LINC00665 overexpression inhibited the proliferation of BMSCs. E. LINC00665 overexpression increased the apoptosis rate of BMSCs. F. LINC00665 overexpression reduced the chondrogenic differentiation of BMSCs. (***P < 0.001, compared with the control group)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X