Comparative analysis of surgical interventions for osteonecrosis of the femoral head: a network meta-analysis of randomized controlled trials

Table 1 Characteristics of studies included in the meta-analysis

References	Year	Country	Design	Treatment	Mean age(years)	Case(hip)	Inclusion criteria	Follow-up (months)	Outcomes
Jayankura et al. [10]	2023	Belgium	RCT	OB	46	23	ARCO I–II	24	Progress, THA
				CD	45	26
Wan et al. [9]	2022	China	RCT	FFG	29.8	45	ARCO II	36	HHS, progress, THA
				VBG	28.8	46
				ABG	30.5	45
				BMG	30.5	46
Zhang et al. [19]	2022	China	RCT	FFG	34.3	29	ARCO II	24	HHS, progress, THA
				VBG	34.4	30
Park et al. [12]	2022	Korea	RCT	BMG	49.3	10	Ficat I–II	36	HHS, progress, THA
				CD	55.6	10
Aggarwal et al. [18]	2021	India	RCT	PRP	35.2	25	ARCO I–II	12	Progress, THA
				CD	38.2	28
Li et al. [7]	2021	China	RCT	BMAC	35.4	22	Ficat I–IV	24	HHS, progress, THA
				BMG	39.4	29
Li et al. [22]	2020	China	RCT	ABG	38.2	20	Ficat II–III	24	Progress, THA
				BMAC + ABG	34.1	21
Hauzeur et al. [8]	2020	Belgium	RCT	BMAC	50	26	ARCO I–II	36	Progress, THA
				OB	51	27
Hu et al. [4]	2018	China	RCT	CD	40.3	65	ARCO I–II	24	HHS, progress
				FFG	40.8	65
Lin et al. [17]	2018	China	RCT	BMG	31.5	16	ARCO II–III	36	HHS, progress, THA
				ABG	32.6	16
Cao et al. [20]	2017	China	RCT	VBG	31	27	ARCO I–III	36	HHS, progress, THA
				CD		27
Li et al. [21]	2016	China	RCT	ABG	36.5	23	Ficat I–II	24	HHS, progress, THA
				VBG		24
Zhao et al. [23]	2016	China	RCT	ABG	33	25	ARCO II–III	12	HHS, progress
				BMG + VBG	30	23
Pepke et al. [11]	2016	Germany	RCT	BMAC	44.5	14	ARCO II	24	HHS, progress, THA
				CD	44.3	11
Tabatabaee et al. [24]	2015	Iran	RCT	BMAC	29.1	14	ARCO I–III	24	Progress, THA
				CD		14
Mao et al. [13]	2015	China	RCT	BMAC: + BMG	34.6	48	ARCO I–III	36	HHS, progress, THA
				BMG	36.1	41
Ma et al. [5]	2014	China	RCT	ABG	34.8	24	Ficat I–III	24	Progress, THA
				BMAC + ABG	35.6	25
Zhao et al. [14]	2012	China	RCT	CD	33.8	44	ARCO I–II	24	HHS, progress, THA
				BMAC	32.7	53

ABG autologous iliac bone grafting, ABG + BMAC autologous bone grafting and bone marrow aspirate concentrate, BMAC bone marrow aspirate concentration, BMG biomaterials grafting, BMG + BMAC biomaterials grafting and bone marrow aspirate concentration, CI confidence interval, CD core decompression, FFG free fibular graft, HHS Harris hip score, MD mean difference, NMA network meta-analysis, OR odds ratio, ONFH osteonecrosis of the femoral head, OB osteoblastic cells, PRP platelet-rich plasma, RCT randomized controlled trial, THA total hip arthroplasty, VBG vascularized bone grafting, VBG + BMG vascularized bone grafting combined with biomaterial

ISSN: 1749-799X