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Table 7 SNP-SNP interaction models of candidate SNPs analyzed by the MDR method

From: Correlation between ESR1 and APOE gene polymorphisms and risk of osteonecrosis of the femoral head: a case–control study

Model

Bal. Acc. CV training

Bal. Acc. CV testing

CVC

p

rs9322332

0.540

0.539

10/10

0.009

rs10872678/rs9322332

0.554

0.511

6/10

0.001

rs10872678/rs9322332/rs7259620

0.585

0.554

9/10

 < 0.001

rs10872678/rs9322332/rs7259620/rs769446

0.605

0.551

9/10

 < 0.001

rs2982573/rs10872678/rs9322332/rs7259620/rs769446

0.623

0.551

10/10

 < 0.001

  1. SNP single nucleotide polymorphism; MDR multifactor dimensionality reduction; Bal. Acc. balanced accuracy; CVC cross-validation consistency; OR odds ratio; 95% CI 95% confidence interval
  2. Bold values indicate statistical significance
  3. p values were obtained using χ2 tests
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X