Table 3 Association between ESR1 and APOE gene polymorphisms and ONFH risk

rs2982573

Co-dominant

TT

358

363

1

TC

136

137

0.96 (0.41–2.26)

0.926

CC

11

11

0.96 (0.73–1.28)

0.780

Dominant

TT

358

363

1

TC + CC

147

148

0.96 (0.73–1.27)

0.790

Recessive

TT + TC

494

500

1

CC

11

11

0.97 (0.41–2.27)

0.950

Additive

–

–

–

0.97 (0.76–1.24)

0.800

rs10872678

Co-dominant

TT

358

305

1

TC

186

184

0.93 (0.48–1.82)

0.832

CC

18

19

1.01 (0.78–1.31)

0.940

Dominant

TT

301

305

1

TC + CC

204

203

1.01 (0.78–1.30)

0.970

Recessive

TT + TC

487

489

1

CC

18

19

0.93 (0.48–1.79)

0.820

Additive

–

–

–

1.00 (0.80–1.24)

0.970

rs9322332

Co-dominant

CC

200

160

1

CA

235

271

0.68 (0.46–1.00)

0.050

AA

70

80

0.69 (0.53–0.90)

0.006

Dominant

CC

200

160

1

CA + AA

305

351

0.70 (0.54–0.90)

0.006

Recessive

CC + CA

435

431

1

AA

70

80

0.84 (0.59–1.19)

0.330

Additive

–

–

–

0.79 (0.66–0.95)

0.013

rs7259620

Co-dominant

GG

245

252

1

GA

218

219

1.01 (0.63–1.63)

0.967

AA

41

41

1.02 (0.78–1.32)

0.880

Dominant

GG

245

252

1

GA + AA

259

260

1.02 (0.79–1.30)

0.900

Recessive

GG + GA

463

471

1

AA

41

41

1.01 (0.64–1.59)

0.970

Additive

–

–

–

1.01 (0.83–1.23)

0.910

rs769446

Co-dominant

TT

421

417

1

TC

83

92

0.29 (0.03–2.82)

0.286

CC

1

3

0.90(0.65–1.25)

0.529

Dominant

TT

421

417

1

TC + CC

84

95

0.88 (0.64–1.22)

0.450

Recessive

TT + TC

504

509

1

CC

1

3

0.29 (0.03–2.87)

0.260

Additive

–

–

–

0.86 (0.63–1.18)

0.360