Correlation between ESR1 and APOE gene polymorphisms and risk of osteonecrosis of the femoral head: a case–control study

Table 2 Basic information and allele frequencies of rs2982573, rs10872678, rs9322332, rs7259620, and rs769446

SNP_ID	Gene	Chr	Base pair	Allele	MAF		HWE	OR (95% CI)	χ2	p
SNP_ID	Gene	Chr	Base pair	Allele	Case	Controls	p	OR (95% CI)	χ2	p
rs2982573	ESR1	6	151,689,399	C < T	0.156	0.156	0.738	1.01 (0.79–1.28)	0.003	0.958
rs10872678	ESR1	6	151,718,829	C < T	0.220	0.219	0.195	1.01 (0.82–1.24)	0.005	0.944
rs9322332	ESR1	6	151,845,666	A < C	0.371	0.422	0.057	0.81 (0.68–0.97)	5.399	0.020
rs7259620	APOE	19	44,904,531	A < G	0.298	0.294	0.524	1.02 (0.84–1.23)	0.033	0.856
rs769446	APOE	19	44,905,371	C < T	0.084	0.096	0.607	0.87 (0.64–1.18)	0.828	0.363

SNP: single nucleotide polymorphism; Chr: chromosome; MAF: minor allele frequency; HWE: Hardy–Weinberg equilibrium; OR: odds ratio; 95% CI: 95% confidence interval; χ²: chi-square
Bold values indicate statistical significance
p value was obtained by χ² test

ISSN: 1749-799X