Fig. 9

Immune checkpoints and Immune infiltration analyses based on CRPS. A Box plots of immune cells and immune function scores of all osteosarcoma samples, compared with high-risk group, the low-risk group has better Immunescores. B Immune checkpoint expression was higher in the low-risk group compared with the high-risk group. C Heatmap of osteosarcoma immune infiltration in different risk subgroups, immune infiltration was better in the low-risk group. D A correlation heatmap showed a positive correlation between RP11-750H9.5 and immune infiltration, while RP11-136I14.5 and RP11-414H17.5 were negatively correlated with immune infiltration. E Violin plot shows that ESTIMATEscore Immunescore and Stromalscore were significantly lower in the high-risk group. (*, **, *** indicate P < 0.05, P < 0.01, P < 0.001, respectively.)