Fig. 4

Validation of the prognostic predictive power of CRPS. Scatter plots of patient survival status in test group (A, C) and all cohorts (B, D). 1-, 3-, and 5-year ROC curves in test set (E) and all cohort (F). ROC curves of CRPS and clinical features were plotted and compared in test set (G) and all cohorts (H), AUC values of CRPS were consistently superior to other clinical features. Significant differences in survival status across risk subgroups were showed by KM curves in test group (I) and all cohort (J). Heatmaps of the risk DECRLs expression of test group (K) and all cohort (L)