Fig. 12

Chemotherapy drug sensitivity analysis to guide individualized treatment of osteosarcoma patients. Box plots showed lower IC50 values for drugs HG-6-64-1, WH-4-023, and WZ-1-84 in the low-risk group, as well as the correlation scatter plots displayed that risk scores were positively correlated to IC50, suggesting that the low-risk group patients would be more susceptible toward these drugs. The opposite was observed for SB52334, suggesting that the high-risk group patients would be more susceptible toward this drug