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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Caulis Spatholobi extracts inhibit osteosarcoma growth and metastasis through suppression of CXCR4/PI3K/AKT signaling

Fig. 2

CS diminishes CXCR4 expression in OS cells. The mRNA and protein expression of CXCR4 in hFOB1.19, Saos-2 and U2OS were assessed using RT-qPCR (A) and Western blotting (B), respectively. Compared with hFOB1.19 group, aP < 0.05. (C) RT-qPCR quantified CXCR4 expression in Saos-2 and U2OS treated with 50, 100 and 200 µg/mL CS for 24 h. Compared with 0 µg/mL group, aP < 0.05; Compared with 50 µg/mL group, bP < 0.05; compared with 100 µg/mL group, cP < 0.05. N = 3; the results are described as the mean ± SD. CS: Caulis Spatholobi

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