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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Caulis Spatholobi extracts inhibit osteosarcoma growth and metastasis through suppression of CXCR4/PI3K/AKT signaling

Fig. 1

CS inhibits OS cell proliferation. A Suppression rates of Saos-2 were ascertained via MTT assay subsequent to exposure to 50, 100, 200, 400, and 800 µg/mL CS for 24, 48, and 72 h. B The half-maximum inhibitory concentration (IC50) was gauged at 24, 48, and 72 h. In comparison with the 24-h group, aP < 0.05; compared with 48 h group, bP < 0.05. C Saos-2 and U2OS cell proliferation following treatment with 0, 50, 100, and 200 µg/mL CS was detected by colony formation assay. Compared with 0 µg/mL group, aP < 0.05; Compared with 50 µg/mL group, bP < 0.05; compared with 100 µg/mL group, cP < 0.05. N = 3; data are presented as the mean ± standard deviation. CS: Caulis Spatholobi

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