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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Long non-coding RNA KCNQ10T1/miR-19a-3p/SMAD5 axis promotes osteogenic differentiation of mouse bone mesenchymal stem cells

Fig. 4

miR-19a-3p directly targets Smad5. A The binding site between Smad5 and miR-19a-3p was predicted by TargetScan online database. The binding interaction between Smad5 and miR-19-3p was tested by decreased luciferase reporter (B) and RNA pull-down (C) assays. D The Smad5 levels were detected by RT-qPCR after KCNQ1OT1 and miR-19a-3p overexpression. **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X