Table 1 Demographic data and clinical information of participants
From: Skeletal complications in patients with hemophilia: a single-center experience
Variables | Haemophilia A (n = 90) Number (%) | Haemophilia B (n = 10) Number (%t) | P value |
|---|---|---|---|
Age at diagnosis (year) | |||
< 1 | 56 (62.2) | 4 (50) | – |
1–5 | 16 (17.7) | 2 (25) | |
5–10 | 6 (6.6) | 1 (12.5) | |
> 10 | 12 (11.1) | 1(12.5) | |
Current age (Y) mean (SD) | 31.6 (14.4) | 30.5 (20.6) | 0.82 |
Severity of disease | |||
Mild | 16 (17.8) | 1 (10) | 0.027 |
Moderate | 1 (1.1) | 2 (20) | |
Severe | 73 (81.1) | 7 (70) | |
Inhibitor | |||
No | 88 (97.8) | 10 (100) | < 0.999 |
Yes | 2 (2.2) | 0 (0) | |
Annual bleeding | |||
1–3 | 19 (21.1) | 4 (40) | 0.306 |
4–6 | 21 (23.3) | 3 (30) | |
7–12 | 45 (50) | 2 (20) | |
< 12 | 5 (5.6) | 1 (10) | |
Treatment | |||
Prophylaxis | 14(15.6) | 4(40) | 0.077 |
On-demand | 76(84.4) | 6(60) | |
Number of joints involved | |||
Single joint | 6 (6.7) | 1 (10) | 0.481 |
Multiple joints | 84 (93.3) | 9 (90) | |
Target joint | |||
Yes | 39 (43.3) | 0 (0) | 0.006 |
No | 51 (56.7) | 10 (100) | |
Radiosynovectomy by 32P chromic phosphate | |||
Yes | 18 (20) | 2 (20) | > 0.999 |
No | 72 (80) | 8 (80) | |
History of surgery | |||
Yes | 16 (17.8) | 2 (20) | > 0.999 |
No | 74 (82.2) | 8 (80) | |
Fracture | |||
Yes | 6 (6.7) | 0 (0) | > 0.999 |
No | 84 (93.3) | 10 (100) | |
Osteoporosis | |||
Yes | 35 (38.9) | 4 (40) | > 0.999 |
No | 55 (61.1) | 6 (60) | |
Hepatitis C infection | |||
Active | |||
Yes | 14 (15.6) | 0 (0) | 0.349 |
No | 76 (84.4) | 10 (100) | |
History | |||
Yes | 26 (28.9) | 0 (0) | 0.060 |
No | 64 (71.1) | 10 (100) | |
Osteoarthritis | |||
Yes | 59(65.6) | 5(50) | 0.489 |
No | 31(34.4) | 5(50) | |