An observational study of an adjusted patient blood management protocol intended to lower rates of transfusion following total knee arthroplasty in patients with preoperative anemia

Table 1 Baseline characteristics

	ACD- (n = 683)	ACD + (n = 68)	p value
Age [years]	71.9 ± 7.9	75.9 ± 9.3	< 0.001
Sex (Female)^§	412 (60.4%)	52 (76.5%)	0.009
BMI [kg/m²]	32.2 ± 6.1	31.7 ± 6.9	0.539
Hb at the preoperative consultation [g/dl]	14.0 ± 1.2	11.3 ± 0.6	< 0.001
Hb the day before surgery [g/dl]	13.8 ± 1.2	12.0 ± 1.0	< 0.001
Chronic antithrombotic drug use^§	269 (39.4%)	30 (44.1%)	0.102
Preoperative EPO^§	1 (0.1%)	28 (41.2%)	< 0.001
TXA use^§	655 (96.0%)	67 (98.5%)	0.503
ASA^§			0.001
- ASA 1	82 (12.0%)	1 (1.5%)
- ASA 2	518 (76.0%)	41 (69.1%)
- ASA 3	82 (12.0%)	20 (29.4%)
Mean corpuscular volume [fL]*	93.4 ± 4.9 (81 – 113)	91.7 ± 6.2 (77.7 – 115.5)	0.008
Preoperative MDRD [ml/mn/m²]	83.7 ± 21.5	72.3 ± 29.4	0.001
Ischemia duration [min]	50.4 ± 18.2	46.7 ± 17.6	0.113

Presented as mean ± standard deviation, except * presented as mean ± standard deviation (range), ^§ presented as number of observations (%). Abbreviations: ACD, anemic chronic disease; ASA, American Society of Anesthesiology; EPO, erythropoietin; MDRD, Modification of Diet in Renal Disease; TXA, tranexamic acid

ISSN: 1749-799X