Fig. 1

SSTZF attenuates disc degeneration in LSI-operated mice. A 2D image of the median sagittal view of L4-5 lumbar spine; the red shear head indicates the L4-5 intervertebral space; B 3D image of the cartilage endplate ossification layer of L4-5 lumbar spine; the red arrows indicate the ossification layer cavity structure; C, D the bone volume of the lower cartilage endplate ossification layer of L4 lumbar spine and the upper cartilage endplate ossification layer of L5 lumbar spine after 4 weeks of modeling; E, F the bone volume of the lower cartilage endplate ossification layer of L4 lumbar spine and the upper cartilage endplate ossification layer of L5 lumbar spine after 8 weeks of modeling, respectively. Data were presented as means ± S.D.*P < 0.05; **P < 0.01; ***P < 0.001; ns: no significant difference. n = 6 for each group