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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Identification of sulfur metabolism-related gene signature in osteoarthritis and TM9SF2’s sustenance effect on M2 macrophages' phagocytic activity

Fig. 1

ssGSEA scores for different gene sets related to glycolysis, OXPHOS, cysteine metabolic process, sulfur metabolic process, and disulfidptosis in synovial samples. A Boxplot shows the ssGSEA score for each gene set in synovial samples. Only the scores of the cysteine metabolic process, regulation of the sulfur metabolic process, and disulfidptosis gene sets are significantly downregulated. The P value is shown at the top of the figure for each group. B The heatmap shows the normalized ssGSEA score for each gene set. C The heatmap shows the expression of DEGs between healthy (red samples) and OA (light blue samples) groups. DEGs: differentially expressed genes between OA and healthy groups

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X